Discovery Life Channel After a lifelong struggle with obesity, the three Perrio siblings travel to Houston in a last-chance journey to lose weight. 2026-08-10 While the Perrios struggle with weight loss, the revelation of a past tragedy explains their resistance to recovery; the siblings must come together to overcome their fears and forge a path to a healthy future. 2026-08-10 After a lifelong struggle with obesity, the three Perrio siblings travel to Houston in a last-chance journey to lose weight. 2026-08-10 While the Perrios struggle with weight loss, the revelation of a past tragedy explains their resistance to recovery; the siblings must come together to overcome their fears and forge a path to a healthy future. 2026-08-10 Lisa's struggle with her weight begins as a child and significantly worsens after witnessing her brother's murder; now bedridden and unable to care for herself, Lisa must find a way to lose the weight, or she will never see her grandchildren grow up. 2026-08-10 With pandemic safety protocols in place, Dr. Lee reopens her office; Monica has a large birthmark growing on the side of her face; Jackie has a melon-sized lump on the back of her shoulder; Reginald has large, rare growths on the back of his head. 2026-08-10 Dr. Lee tries to provide the help Reginald needs to remove the large, rare growths on the back of his head; Che're has a prominent bump on her face that has put her in a dark place; Juan has several painful boils on the back of his neck. 2026-08-10 Dennis has several giant growths on the back of his head; Juan has a rare condition he hopes Dr. Lee will understand; Natalie searches for answers as to why her body is covered in hundreds of mysterious dark bumps. 2026-08-10 Audrey pops the painful bumps that cover her body so she can feel relief; Felicia has a peculiar-looking dark growth on her forehead; Krista's excessive sweating is so severe that on any given day she could fill up an entire milk jug with her sweat. 2026-08-10 John fears the large lump on his neck could become so big that it may eventually suffocate him; Shoshana is depressed because of the big growth on her forehead; Ashley hopes Dr. Lee can provide some relief from her three painful skin conditions. 2026-08-10 Yaellie, 9, has itchy psoriasis on over 90 percent of her body; former U.S. Marine Matt has a large recurring lump in his armpit; twins Tracie and Stacie have numerous matching bumps on their heads that sometimes leak. 2026-08-10 Joanne has been held back from success because of her forehead growth; Shakisha split her left earlobe after stretching it with gauges; Mike is a tough guy with a soft bump on his head; Dania's rhinophyma has kept her from enjoying her life. 2026-08-10 James has a large, squishy lump on his forehead; Tanisha has a growth on her arm and itchy scars all over her body; Ed wants his stomach lump removed before his girlfriend gets out of prison; Justin has painful mystery bumps all over his head. 2026-08-10 JD is a gentle giant with a pear-shaped mass hanging off of his ear; David has two bumps on his neck and one on his finger that give him pain; Julie hopes Dr. Lee can remove her large back growth so she can return to the sea. 2026-08-10 Stephen's large, bulbous nose gets him unwanted attention, and he hopes Dr. Lee can help; Veronica wants to be free of secrets, including the bump on her butt; Marty has a large, 30-year-old growth on his shoulder that he is ready to remove. 2026-08-10 Brittany has been called a monster due to her genetic condition that causes head-to-toe bumps; Leonardo has a fist-size growth on his head, but he is terrified of doctors; Tamyra has skin so thick that she shaves the bottom of her feet for relief. 2026-08-10 Jaclyn has a lump on the back of her head that causes her emotional distress; Shane has a growth between his eyes that could put him in danger at his electrician job; Brittany has seen multiple doctors about the sores on her body with no answers. 2026-08-10 Stacey's shoulder growth prevents her from being the playful teacher she once was; Matthew worries that his mysterious shin rash may be dangerous. 2026-08-10 Lattyse was born with a mysterious growth above her eyebrow that gives her headaches. Robert has a tomato-sized growth on his butt cheek that causes him pain and discomfort. Sharon has an embarrassing, stinky, squirting cyst under her breast. 2026-08-10 J-Fab is the life of the party, but her shoulder bump is seriously cramping her style; Dan is a gentle giant with lumps on his head that add a few inches; Teresa's red face and bumpy nose make her feel like a monster. 2026-08-11 Fit guy Alonso wants to show off his progress in the gym, but his 70 lipomas are holding him back; Porscha is a comic book enthusiast with two symmetrical lumps on her face; Jeffrey has a leaky lump named Larry on the back of his head. 2026-08-11 Robert carries the weight of providing for his family and the weight of the huge lump on his head; Christina has liquid-filled growths next to her eyes; Felipe, a photographer with a dry skin condition so severe he risks losing his career. 2026-08-11 Natasha has ambitions of becoming a model, but her massive ear keloids are keeping her off the runway; eight-year-old Wynter wants her scaly mermaid skin cured; Dr. Lee's bestie, Raquel, needs help with a new product for a private area. 2026-08-11 J-Fab is the life of the party, but her shoulder bump is seriously cramping her style; Dan is a gentle giant with lumps on his head that add a few inches; Teresa's red face and bumpy nose make her feel like a monster. 2026-08-11 Fit guy Alonso wants to show off his progress in the gym, but his 70 lipomas are holding him back; Porscha is a comic book enthusiast with two symmetrical lumps on her face; Jeffrey has a leaky lump named Larry on the back of his head. 2026-08-11 Robert carries the weight of providing for his family and the weight of the huge lump on his head; Christina has liquid-filled growths next to her eyes; Felipe, a photographer with a dry skin condition so severe he risks losing his career. 2026-08-11 Natasha has ambitions of becoming a model, but her massive ear keloids are keeping her off the runway; eight-year-old Wynter wants her scaly mermaid skin cured; Dr. Lee's bestie, Raquel, needs help with a new product for a private area. 2026-08-11 Stacey's shoulder growth prevents her from being the playful teacher she once was; Matthew worries that his mysterious shin rash may be dangerous. 2026-08-11 Lattyse was born with a mysterious growth above her eyebrow that gives her headaches. Robert has a tomato-sized growth on his butt cheek that causes him pain and discomfort. Sharon has an embarrassing, stinky, squirting cyst under her breast. 2026-08-11 Doctors treat a gunshot victim who has a life-threatening wound to the head. 2026-08-11 Staff treats patient injured while engaging in risky behavior at night. 2026-08-11 Medical staff treats a patient who was hit by a train while crossing the tracks. 2026-08-11 Medical staff treats patient injured in a car wreck involving multiple vehicles. 2026-08-11 A man who lost a kidney to cancer, damaged his heart with heroin and is HIV-positive; man with cardiac failure; car crash victims. 2026-08-11 Victims of car crash, scalding, burn. 2026-08-11 Victims of shootings, stabbings, heroin overdose. 2026-08-11 An accident victim is trapped in her car all night; a 3-year-old gets popcorn stuck in her ear; a man's leg is nearly severed; a man coughs up blood; a man shoots his own hand. 2026-08-11 A car crash victim with internal bleeding; a potential stroke victim; a sawmill worker with a piece of wood piercing his nose. 2026-08-11 A successful businesswoman suddenly seems to become possessed by demons; a young college student battles monstrous pain when she grows fingernails out of her hair follicles. 2026-08-11 A mother becomes a recluse when every sound becomes deafeningly loud; a man's career is in jeopardy when he gets drunk without touching a drop of alcohol. 2026-08-11 A dad is accused of child abuse when doctors discover his baby has broken bones; a vibrant teenage girl is unable to eat and is wasting away before her mother's eyes. 2026-08-11 A woman has seizures whenever she hears her favorite pop tunes; a young athlete loses all his body fat and almost starves to death. 2026-08-11 A man who had a full-face transplant faces another life-threatening challenge; a boy with a talent for singing is prematurely aging; in a Peruvian village, boys and men go blind by the age of 50. 2026-08-11 A man undergoes surgery to remove his record-breaking face tumor; a young girl lives with huge hands; a mathematician born with severely deformed legs and a spine walks on all fours. 2026-08-12