Discovery Life Channel

A toddler cannot walk or stand.

A teenager fails to hit puberty; a collapsed lung.

A teen's leg grows so large it affects his mobility.

A woman starts growing uncontrollably.

A woman surviving blindness and albinism suffers another disease.

A toddler has unexplained bleeding; a college student has intense cramps.

After meeting and falling in love at a bariatric rehab center, Lee and Rena are battling health and anger issues while taking a desperate, second attempt to save their relationship and their lives.

An overweight woman struggles with flesh-eating bacteria and butterfly shaped fat deposits; unexpected news threatens her weight loss journey.

Laura has used food to cope with her emotions; she is confined to a wheelchair and relies on an oxygen tank to breathe and her husband and mother to survive.

A woman whose extreme obesity has left her nearly immobile must overcome both her physical and emotional pain if she is ever to live a normal life again.

Alicia, all smiles and laughter on the outside, secretly fears that her food addiction will kill her before she can marry her long-time love or watch her nieces grow up.

Liz, completely bed-bound, has severe lymphedema that makes it impossible to walk; utterly isolated, Liz has no friends, battles depression and lives with a mother too ill to take care of her.

Unable to stand for more than a short period of time, Karina's weight places a burden on her parents and drives a wedge between her and her sister.

Lisa's struggle with her weight begins as a child and significantly worsens after witnessing her brother's murder; now bedridden and unable to care for herself, Lisa must find a way to lose the weight or she will never see her grandchildren grow up.

After years of a tumultuous relationship with her husband, Tamy's eating addiction has caused her weight to balloon to over 500 pounds; she has become a hermit and hopes to restart her life so she can better care for her son, Zachary.

Fearing he'll suffer the same fate as 700-pound brother David, Benji hopes to be able to support both himself and his brother on their life-or-death weight loss journey.

After years of a tumultuous relationship with her husband, Tamy's eating addiction has caused her weight to balloon to over 500 pounds; she has become a hermit and hopes to restart her life so she can better care for her son, Zachary.