Discovery Life Channel

A 25-year-old woman becomes paralyzed from the chest down; an unknown condition steals a woman's eyesight.

A mother becomes a recluse when every sound becomes deafeningly loud; a man's career is in jeopardy when he gets drunk without touching a drop of alcohol.

A dad is accused of child abuse when doctors discover his baby has broken bones; a vibrant teenage girl is unable to eat and is wasting away before her mother's eyes.

Diana, a once thin and active woman, is now a prisoner to her body and trades the comfort of her apartment for a weight loss journey under the strict authority of her niece.

Christina has not left her house in two years due to her size; she has eaten herself into a state that will soon kill her if she does not change.

Paula has built a wall around herself to push people away; when she suddenly loses a loved one she can no longer ignore the threat of losing her own life.

Vianey and Allen are locked in a co-dependent relationship based on a shared love of food; as they head to Houston, they will soon find out if their relationship can handle the strain of growing healthy together.

Shantel's brother Carlton lives downstairs but she hardly ever sees him because at 600 lbs each, neither can do the stairs safely; to break free from a death spiral of codependent eating they need Dr. Now's help to reforge their sibling relationship.

Isaac helped raise his siblings after his mom suffered a debilitating stroke when he was 10. While learning to cook for his family, he began comfort-eating. Now to avoid eating himself to death, Isaac must learn to take care of himself for a change.

A lifetime of abuse has left Michael anxious and afraid to leave the house; with the help of his devoted wife, he must follow Dr. Now's program to keep from eating himself to death.

Lisa wouldn't have made it this far without the help of her chief enabler, her boyfriend Randy; when Randy falls ill, Lisa finds out if she has the will and determination to turn her life around.

As an Italian American, Geno was raised with lots of love, family and food; now, he's still living with his mom and eating himself to death, and it's time to make a change; Geno's cousin, Nico, joins the cause; they pledge to lose weight together.

Latonya found the man she wants to marry; the only problem is that, at almost 700 pounds, she can't walk down the aisle; Latonya doesn't want to give up the food that she's used to, but she may do it for love.

As an Italian American, Geno was raised with lots of love, family and food; now, he's still living with his mom and eating himself to death, and it's time to make a change; Geno's cousin, Nico, joins the cause; they pledge to lose weight together.