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Regain independence and enjoy greater mobility with the compact design and long-lasting battery of portable oxygen.

Learn what's behind mental decline with age, and how to improve memory, focus and concentration with NeuroQ's Darrin Peterson and Dale Bredesen MD.

See how one company is changing people's lives by helping them put their tax problems to rest.

Meet the new Shark PowerDetect Upright Vacuum with features like DuoClean Detect Technology, self-cleaning brush roll and odor neutralizing, and you will be cleaning faster, smarter and better!

The guys teach a crash course in sorry behavior, ask strangers to settle bizarre debates, and spread surprisingly good news at the mall; tonight's loser has his hands tied when a day at the park turns into a frightful mess.

The guys give a security presentation that's anything but safe, then hold hands with strangers in the park; tonight's big loser quickly becomes an unwanted guest while clowning around at a kid's birthday party.

The guys take over New Orleans, as they steal sips from strangers' drinks at a famous bar, spin the Wheel of Voo-Doom on Bourbon Street, and crash some horse and buggy rides; tonight's loser turns into a legendary swamp monster.

The guys ask strangers to agree with their bizarre points of view and give classless lessons about real estate.

The guys get extra cheesy at a pizza parlor, then head to Wall Street where they ask strangers to help translate bizarre text messages in Spanish; trapped in a haunted house, a nightmare comes to life for tonight's big loser.

The guys take in more than they bargained for while working at a tailor shop and convince strangers to hand over their cell phones; tonight's big loser sacrifices his childhood for a punishment three months in the making.

Joe, Sal, Q, and Murr pose as waiting room receptionists and then pitch to a focus group; things get interesting on a road trip that drives tonight's loser to the edge.

Joe, Sal, Q, and Murr pose as documentary subjects; the guys go looking for fights in a public park; one joker must crash a poetry slam.

The guys play receptionist for the day; teaching parents proper home-schooling techniques; dreams come true as one joker lands the endorsement deal of a lifetime.

The boys learn how hard it is to find good help these days; the guys return to their artistic roots; one joker reluctantly delivers a series of crushing blows.

The guys get greedy with fellow shoppers at the market, then offer major disservices to a focus group; tonight's big loser learns that the grass is always pinker on the other side.

Highlights of some of the most outrageous twists on challenges and punishments.

Q, Joe, Sal and Murr pose as avant-garde photographers in a Staten Island park and get fully animated when pitching to a focus group; just when tonight's big loser thinks it's in the bag, he still comes out painfully behind.

Joe, Q, Sal, and Murr offer evocative responses while taste-testing new foods; the loser gets sent to a place far, far away.

Q, Sal, Murr, and Joe help jobseekers land their next big gig; then, they meet with a focus group to pitch their memoirs; the losing joker must deliver the news.

Sal, Murr, Joe, and Q dig deep into strangers' past lives to deliver the hard truths, and they enlist volunteers to help them craft the perfect email; tonight's big loser has a larger-than-life identity crisis.

Murr, Joe, Q and Prince Herb pitch out the year's hottest new TV shows to would-be viewers and enlist volunteers into a variety of totally normal focus groups; the big loser must deliver the performance of a lifetime.

Joe, Q, Prince Herb and Murr recruit new senior executives for their companies and then jump into the dating pool; the big loser gets an opportunity to show off his musical chops to a captive audience.

Q, Prince Herb, Murr and Joe try their hardest to prove they're advertiser friendly, and then tell strangers their life stories; the big loser schools the academic community.

Murr, Joe, Sal and Q participate in the documentary filmmaking process, then read a teenager's diary to surprise and delight strangers; when they lose, they find motivation to do better next time.

Joe, Sal, Q and Murr showcase their creative vision by unveiling their new inventions and learn what it takes to get a date in the digital age; the losing joker embraces the role of a lifetime.

Murr, Q, Joe and Sal prove their good taste, and later prove they can hack it in the professional world; the safe guys give the losing joker a semi that he must show off to an unsuspecting crowd.

Sal, Q, Murr, and Joe take the law into their own hands, and they misplace the trust of their own children; finally, the losing joker must pod up with a stranger.

Four longtime friends compete to embarrass each other with a series of hilarious dares; if they refuse, they lose.

Sal, Q and Murr clear the room as eccentric exterminators and produce a controversial infomercial; comic Eric André drops by to give the losing Joker an awkward release.

Q, Murr, and Sal learn a tough lesson about the corporate chain of command before starting a white-collar revolution; the losing joker must play husband to special guest Jillian Bell.

Sonny Vaccaro and Nike pursue basketball rookie Michael Jordan, creating a partnership that revolutionizes the world of sports and contemporary culture.

Adoptable rescue dogs showcase their personalities and hockey skills in the Stanley Pup competition.

Sonny Vaccaro and Nike pursue basketball rookie Michael Jordan, creating a partnership that revolutionizes the world of sports and contemporary culture.