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When the leader of a drug cartel and one of the world's most wanted men is apprehended by the team, the entire FBI headquarters is put at risk when his henchmen unveil a plot to free him; Isobel must make a difficult decision.

A shooting at a quinceañera leaves two dead, but the team believes they may not have been the intended targets; Maggie is conflicted as the team decides the best plan of action for using a witness to take down their suspect.

The team searches for a young girl who was kidnapped from a cabin during a family vacation; Maggie questions her relationship with Nestor when she learns he hasn't been completely honest with her.

The team must infiltrate a drug trafficking gang after the robbery of a chemical plant leaves two customs agents dead; Nestor offers his help on the case, giving Maggie new insight into his character.

The team hunts a killer who is fatally shooting seemingly unrelated targets; new agent Tiffany Wallace experiences tension between her work as an FBI agent and the responsibility she feels to her community as a Black woman.

After a bomb leaves three people dead, the team presses a reluctant informant to gather information from his close friends who are under suspicion; OA and his girlfriend clash over where the informant's rights lie.

At Halloween, the team takes on a case to prove the existence of ghosts on the Queen Mary but find a ship on a deadly collision course; Walter considers taking note of Paige's interests to benefit their relationship.

A device that can prevent a nuclear meltdown is tracked through the Los Angeles sewers; Walter learns to listen and not offer advice to Paige; the team meets their new neighbor.

Team Scorpion visits a renaissance festival, but the revelry is cut short when a group tries to rob a nearby police evidence locker; Paige grows weary of Walter pointing out the historical inaccuracies at the festival.

Team Scorpion becomes stranded on a floating island of trash they were trying to destroy; Toby works with Cabe to uncover the details of his father's death.

Team Scorpion tries to help a father and his daughter when their plane crashes nearby; Paige helps Walter navigate his feelings about Cabe's possible future in prison.

The team anxiously awaits the verdict of Cabe's trial which could send him to prison; they use their nervous energy to try saving a dog stuck in a cistern.

When a BAU member gets in trouble in Mexico, the team enlists the services of the International Response Team for help.

The BAU looks into the cause of several fatal car crashes involving drivers and pedestrians; Reid gets bad news.

The BAU investigates a series of disfiguring acid attacks on young men and women; Dr. Reid begins to settle into his new surroundings.

A mother steps forward with valuable information for the BAU to aid in their investigation of an unsub known as the bone crusher; Reid must adapt to a new set of rules in prison.

The BAU believes two unsubs may be operating simultaneously when victims killed in two different ways are discovered in the same city; the team grapples with keeping Reid safe in prison.

The BAU investigates an urban vampire who kidnaps his victims at night and holds them underground in the sewer system; Reid makes a difficult decision in prison.

The BAU is called to investigate after three victims are discovered tied to stakes in the brutal Arizona desert.

The BAU investigates when several federal government employees, including a close friend of Walker's, succumb to symptoms of a heart attack; Reid anxiously awaits his trial date.

Wade's son asks Pride for help after being attacked and discovering his girlfriend is missing; Pride must meet with a therapist to discuss his process for solving cases.

Pride starts to doubt evidence suggesting homeless kids murdered a petty officer.

Rita Deveraux tells Pride that Douglas Hamilton is about to make a deal to get out of prison; Pride and the team re-investigate the Clearwater case in hopes of spoiling his plans.

After a deadly armed robbery and high-speed chase is linked to an undercover ATF operation, Percy reconnects with her former ATF partner.

When a reporter is kidnapped and held without a ransom demand, the team must dig into her past relationships in order to pin down her assailant's motive; Isobel's relationship comes under fire when the case makes a connection to her boyfriend.