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Police arrests a woman for alleged assault; she reportedly bites, kicks and spits at officers.

Police pursue an armed suspect on a freeway; robber hijacks an 18-wheeler in Fort Lauderdale, Fla.; police in St. Petersburg, Russia, chase a drunk driver in a tractor trailer.

After an officer gets a drunk driver off the road, another one crashes the scene; an officer gets ambushed after pulling over an armed ex-con; an officer keeps a firm grip on a suspect trying to drive away.

Lynn Ann Jackenheimer goes on a Fourth of July vacation with her two young children and her boyfriend to the Outer Banks of North Carolina, hoping for some quality family time after a rough period in her life.

Each episode investigates a real murder that took place in an exotic locale, while the victim should have been enjoying the trip of a lifetime.

Murderers with obsessions of love, jealousy or power.

Microscopic pieces of evidence -- a fingerprint or a few fibers -- left at the crime scene can lead to the conviction of such killers as David Middleton and Gregory Kokal.

When a Hollywood cameraman is found shot to death, it takes two years for investigators to piece together the evidence and uncover layer upon layer of hired killings in order to hide the identity of the person behind it all.

Ontario police conduct a manhunt for the prime suspects in four brutal murders.

Old-fashioned police work and computer animation determine how a 15-year-old boy was shot while inside a Dallas gun club.

Investigators use blood evidence to convict a man of murdering his wife.

Scientists and detectives use DNA to solve a string of rapes and murders.

Police use DNA profiles of seed pods from a truck to catch a killer.

Police have few leads to follow after a parole officer is found shot dead in his car.

Detectives follow the electronic crumbs left behind by cell phones, surveillance cameras and ATMs to track criminals.

Despite a massive search, a missing woman was never found; a private detective suggests that the missing woman's husband is responsible, and he is arrested.

Officials who are given authority take their actions too far.

A 45 year old woman dead after an argument; an immigrant dies suddenly.

The sensitive nose of a forensic examiner sniffs out murder.

Discovering that an assault suspect is left-handed is crucial to a police investigation dating back 16 years.

Forensic scientists try to find a way to "lift" the serial number from a shotgun that's their only clue in a case.

Investigating the worst arson spree in U.S. history -- a rash of more than 75 fires near Seattle.

Using technology to solve crime.

Mother of three, Dianne Hood, is shot to death by a masked gunman on her way home from a Lupus support meeting; police initially assume it's a robbery, but Lt. Joe Kenda uncovers a sordid web of lust and greed.

A nocturnal killer preys on senior citizens in 1997 Louisiana.

A note claiming a family emergency was all that was left behind when American Atheist Madalyn Murray O'Hair and her family vanished in August 1995.

A college student is abducted in the middle of the night.

Jane turns down advances of a fellow student; Jim retaliates by doing a video project that will have a deadly conclusion.

Awakened by noises, a couple's worst nightmare becomes a reality as intruders shoot and kill their beloved daughter, Terri Ann McCoy; investigators work through leads and lies to discover the perpetrators are closer than they realized.

A collection of real-life videos covering some of the "Most Shocking" police chases, dangerous encounters and acts of criminal behavior. Shot from all perspectives, these videos are tense, thrilling and unbelievable. From bar fights that get out of hand to hostage standoffs with police to high-speed car chases, the action and danger of people out of control is caught on tape.

A thief with a load of personal watercrafts leaves a trail of destruction; a drunken man behind the wheel of a dump truck leads police on a wild chase; a drug-crazed driver runs out of road.

Murderers attempt to conceal evidence.

Chaotic or clean, a murder scene will yield clues left behind by the culprit, as was amply demonstrated in the case of the "Night Stalker.".

Female killers tend to choose less violent methods.

When a prominent business man is killed by a bomb in his car, thirteen years pass until investigators are able to uncover a trail of secret love affairs and financial receipts to lead them to the most unassuming killer.

A search mission for three women missing in Yosemite Park turns to a murder investigation when two are discovered in the trunk of their burned out car.

Police believe they have a serial rapist and murderer, but DNA testing and research leads to another arrest and conviction.

In 1976, 182 war veterans in Philadelphia become hospitalized with pneumonia-like symptoms and 29 die; the disease resurfaces every few years.

After a wealthy Southern physician gets murdered with a baseball bat, his wife and a handyman become convicted of the crime.

Investigators solve the 1988 murder of a drifter in Southern California by examining a species of fly found near the body.

A teenager and a middle-aged man rob and try to murder another man and his 80-year-old mother.

A man robs Wells Fargo Bank in Albuquerque, N.M., on Aug. 10, 1999, claiming the money would be used to feed poor Mexican children.

People who contract killings have air-tight alibis, but investigators use forensic science to explode so-called perfect alibis.

When Brandi Peters and her three children were found murdered, prosecutors pointed the finger at her ex, but as the trial got underway, an imprisoned drug dealer came forward.

Employees break the law at work and get arrested.

A man is found dead by his girlfriend; a pregnant teen is found dead in bed.

Computers aid the police and FBI in solving a string of crimes.

Using an anonymous letter and geographical profiling, investigators close in on a serial rapist, and a cleverly obtained DNA sample confirms their suspicions.

When a young boy has serious respiratory problems and his father shows signs of early Alzheimer's disease, a chance encounter with a stranger kicks off an investigation into the cause.

Police in St. Petersburg, Fla., use cell phone mapping, wiretapping and a host of forensic evidence to find a surgeon's killer.

Murder weapons often hold several critical forensic clues about the crime.

Housewife Elsie Jennes is found dead in the basement of her burning home; Lt. Joe Kenda has no leads until Elsie's son, William, turns up.

Agents link a string of bank robberies in Texas to similar heists in California.

Handyman Cary Stayner is accused of murdering three Yosemite National Park tourists.

An 8-year-old boy's body is found.

A young, single mother's co-worker is found raped and murdered and she fears that she is next.

In Cleveland, Okla., the townspeople experience heartbreak when their esteemed sheriff is gunned down in the night; as the community wrestles with its safety, law enforcement personnel are determined to find justice for their fellow officer.

A criminal attacks a police officer, triggering a shootout; a drugged-out felon takes on a patrolman in broad daylight; a gang of thieves raids a clothing store, opening fire on a helpless clerk.

A Mardi Gras bash explodes into a free-for-all; a brawl erupts at a peewee football game after a hot-headed coach punches a referee; angry veterans use homemade flamethrowers against police during a riot.

As cocky serial killers become increasingly careless, investigators harvest the clues that will ultimately put them away.

Poisoners rely on their victims' trust.

When forensic scientists re-examine old, unsolved crimes, they sometimes find an overlooked clue or employ new technologies.

When a vibrant bisexual woman is found dead, her Craigslist lover blames the victim's boyfriend; a tip from a hit television show reveals the true killer, leading to a chase around the world in an attempt to place them behind bars.

A nurse is the main suspect of five bodies found in a wooded area in central Florida.

In 1971, John List disappears after murdering his mother, wife and three children; he eludes the law for years until an age-scaled sculpture of the suspect and a true-crime TV program helps lead to his arrest in 1989.

An 11-year-old boy comes down with a fever and diarrhea after eating an undercooked burger; when his condition worsens, his mother drives him to a hospital and doctors discover E. coli destroying his body.

Florida police search for a serial rapist and murderer who left small red fibers on each of his 10 victims.

When an English couple go missing, police suspect their son killed them and must rely on mud and blood samples found in the couple's two cars to find their bodies.

On July 4, 1987, a convicted assassin breaks into the computer room of a penitentiary in New Mexico and frees six other inmates.

On Aug. 12, 1997, a man wearing a stocking mask, gloves and a baseball hat robs Norwest Bank in Scottsdale, Ariz.

The role of the Texas Rangers, formed in the 1830s, continues to evolve with the application of medical jurisprudence.

Popular college senior Samantha Josephson goes missing after a night of socializing at a bar area popular with students; tragically, her body is found 24 hours later with more than 100 stab wounds.

Mixologists drink on the job and get arrested for driving under the influence.

A man dies after hunting; a 72 year old woman dies after choking and coughing.

After a man's body is discovered a few miles from his home, authorities trace the crime back to his house and question his wife.

A random serial sniper is plaguing Virginia and Maryland, with no profile of their victims.

A woman wins her release after being imprisoned for allegedly killing her mother in a car fire.

Authorities are able to apprehend a kidnapper because he allowed his victim to write a will on a telltale pad of paper.

Fire, water, earth - killers call on all the elements in their attempt to cover up their crimes.

Teen runaway Maggie Fetty is found strangled to death on a mountain road; an anonymous tipster blames Maggie's best friend, but she accuses a patient with multiple personalities.

A bank robbery provides clues to a home break-in and shooting.

The murder of Jamie Paxton mirrors multiple deaths in the Ohio area; a psychological profile leads authorities to Thomas Lee Dillon as a prime suspect in the murders.

A business traveler is found dead in a hotel room.

Businesswoman Mary McIntyre reveals what happened when she hired a man who became dangerously obsessed with her.