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Screening bodies for toxins helps identify the true cause of death.

When a man arrives at the home of his mother, he realizes the car parked in front has a broken window. After he enters the house he finds the lifeless body of his mother.

When questionable abuse allegations are proven false, Greg and Diana divorce; shortly after, one of them is contacted by a private investigator and lured out to a dirt road; maybe the sniper in the bushes is there to commit a murder.

A 28-year-old woman found dead in her bed; a man dies next to a gun, knife and pill bottles.

When Catherine Edwards misses a family outing, her parents check on her; at her apartment they discover Catherine's body; investigators follow dozens of leads as the alarmed community worries about a killer on the loose.

When an unidentified burned corpse is found in a field, state-of-the-art forensics is turned to.

Law student Adrienne Hickson fatally stabs her boyfriend Shawn Washington with the knife for her birthday cake when he helps his friends move instead of spending the day with her.

Applebee's waitress Rachel Wade, 19, stabs 18-year-old Sarah Ludemann to death in a vicious teen-girl cat fight over shared bad boy boyfriend Josh Camacho.

Teenager Adrianne Reynolds dreams of a fresh start, but instead becomes the victim of a chilling plot orchestrated by classmates she believed were friends. Detectives uncover a shocking murder that exposes jealousy, manipulation and betrayal.

Hardware store clerk Sydney Loofe vanishes after an online date and investigators race to find her.

The Atlanta murder trial of prominent lawyer Tex McIver, who claims his gun accidentally went off, unintentionally shooting his wife in the back as they drove home.

A confession from a psychopath Robert Spangler as he reveals his role as a serial spousal killer.

A nationwide FBI manhunt for a sniper who targets African-American men, leaving no clues or witnesses.

Following her divorce, Cristi buys a new home that needs some work and hires a handyman who becomes fixated on her.

Criminals are betrayed by the clues their own bodies leave behind.

Todd Kendhammer calls 911 in a panic, describing a freak accident involving his wife; police are suspicious of Todd's responses in the interrogation room; forensic details from the autopsy report cast further doubt on his story.

On a summer night, Amanda Colley returns to a ransacked house; her love interest Lamar and two girlfriends arrive to join her, and gunshots ring out; Amanda and her friend Lindy are found dead.

Victims' families and friends can provide crucial information in investigations.

Killers sometimes disguise their crimes as accidents.

Everyday substances reveal hidden clues that break a homicide case.

After a young woman's corpse is found and the evidence points towards her abusive husband, it takes 30 years until a mysterious woman surfaces to reveal that the true killer is actually her own husband.

When two members of the powerful Murdaugh family are murdered, law enforcement is faced with a town swirling with gossip, grudges and lies. Without an obvious suspect, police turn to digital forensics to find evidence that.

Just because some people are young, doesn't mean they're above the law.

Hardware store clerk Sydney Loofe vanishes after an online date and investigators race to find her.

Serge Archambault is known as the "Butcher of St. Eustache" due to the vicious manner in which he killed his victims.

Some multiple-murderers seem to choose victims at random, without an apparent connection.

The agency charges James Springette with trafficking drugs into the United States.

A 45-year-old woman dead after an argument; an immigrant dies suddenly.

The sheriff's office respond to a 911 call from a distraught husband, who claims his wife has killed herself with a gun; once on the scene, detectives uncover chilling evidence that turns the case into a murder investigation.

The largest police investigation of the decade lasted 23 days to catch a sniper who terrorized Washington, D. C. residents.

A submissive wife, Mary Winkler, takes fate into her own hands, before fleeing the scene for a day at the beach with her children.

Encouraged by life insurance money, 33-year-old Kimberly Hricko takes her 35-year-old husband Stephen on a romantic murder mystery weekend.

Angela Craig repeatedly falls mysteriously ill before dying in hospital. Detectives soon suspect her husband, dentist James Craig, has been poisoning her. Secret affairs, suspicious internet searches.

Doreen Bradley, owner of a successful fast food restaurant, is found murdered in her home.

After trying for 20 years to solve the mystery of a 6-year-old boy found dead in the woods, an artist's age progression portrait of the child posted on social media leads detectives to find new clues.

Pamela George's beaten body was found and two boys from successful families are charged with first degree murder.

White-supremacist brothers embark on a cross-country crime spree.

When single mother Rosita accepts a stranger's friend request, she has no idea he's hiding a terrifying secret that will lead to a deadly game of cat and mouse.