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NBC News provides viewers with the latest national and international news; consumer, health and personal finance reporting; up-to-the-minute local news.

A young Tennessee woman mysteriously vanishes and misses her family's Thanksgiving dinner; determined to track her down, her family takes matters into their own hands, pursuing every digital clue she left behind.

The key to "Scrambled Up" is its simple, fast and fun format. Four players compete to be the first to correctly unscramble word puzzles. Colorful tiles slowly rearrange themselves while players are given clues to the answer. Host Michael Yo.

The key to "Scrambled Up" is its simple, fast and fun format. Four players compete to be the first to correctly unscramble word puzzles. Colorful tiles slowly rearrange themselves while players are given clues to the answer. Host Michael Yo.

Confidence quickly turns into second-guessing -- do they lock in the right word or overthink it into chaos?

The team circles the answer forever while time vanishes. Can they finally stick the word before the buzzer ends it?

Sheldon's stage fright stands between him and a coveted award.

A syndicated news magazine includes investigative reports, interviews with newsmakers, human interest stories and celebrity and pop-culture features.

Stay informed with the latest breaking news and headlines.

Tom Llamas anchors the latest news, going beyond the headlines to see how lives are affected by the world around them.

Stay informed with the latest breaking news and headlines.

Sheldon and Amy's relationship is tested when she takes a job at his university; a fight with Bernadette leaves Howard sleeping on Raj's couch.

AGT celebrates 20 years of unforgettable talent, iconic, viral moments and global impact; with a new mega-mix performance and judge interviews, the special examines the show's legacy and how it redefined talent TV.

Jimmy Fallon and celebrity guest Chance the Rapper pair up with contestants and face off over two games; players from each team guess secret passwords using only one-word clues for a chance to win up to $25,000.

Stay informed with the latest breaking news and headlines.

Actress Tina Fey; actor Marlon Wayans; baseball player Jazz Chisholm Jr.; a performance from Schmigadoon!

Actor Brett Goldstein; author David Sedaris.

Stay informed with the latest breaking news and headlines.

Reporting of breaking news and developing stories in real time.

This early-morning news covers overnight events, breaking domestic and international news as well as a preview of the day's anticipated events. The program also presents regular reports from the worlds of business, entertainment and sports.

This early-morning news covers overnight events, breaking domestic and international news as well as a preview of the day's anticipated events. The program also presents regular reports from the worlds of business, entertainment and sports.

This early-morning news covers overnight events, breaking domestic and international news as well as a preview of the day's anticipated events. The program also presents regular reports from the worlds of business, entertainment and sports.

Stay informed with the latest breaking news and headlines.

Stay informed with the latest breaking news and headlines.

Thrift shopping with Christine Romans; actors Jennifer Lopez and Brett Goldstein ("Office Romance"); contributor Makho Ndlovu; actor Nicholas Galitzine.

Advocating for oneself at the doctor's office with Dr. Akshay Syal; Gerber Baby winner reveal; rapper Jeezy; summer travel hacks and essentials with Sarah Eggenberger; Today Food with Claudette Zepeda.

Actor Marco Calvani; Rabbi Steve Leder and friar Jonah Teller.

Exploring the challenges and triumphs of aging, and celebrating the wisdom, strength and beauty that come with life's later stages.

Stay informed with the latest breaking news and headlines.

NBC News provides viewers with the latest national and international news; consumer, health and personal finance reporting; up-to-the-minute local news.

A beloved Staten Island teacher is found dead in the home she shared with her husband; an unknown number in her cell phone leads investigators to reveal troubles in her seemingly idyllic life -- and to ultimately unearth her killer.

The key to "Scrambled Up" is its simple, fast and fun format. Four players compete to be the first to correctly unscramble word puzzles. Colorful tiles slowly rearrange themselves while players are given clues to the answer. Host Michael Yo.

The key to "Scrambled Up" is its simple, fast and fun format. Four players compete to be the first to correctly unscramble word puzzles. Colorful tiles slowly rearrange themselves while players are given clues to the answer. Host Michael Yo.

The clock is loud and the word won't click -- do they stay calm and connect the dots before the buzzer?

The clues point in the right direction, but the answer stays hidden. Will they locate it in time -- or keep searching?

Penny and Leonard have a fight that threatens their relationship; Sheldon and Wil Wheaton face off once again.

A syndicated news magazine includes investigative reports, interviews with newsmakers, human interest stories and celebrity and pop-culture features.

Stay informed with the latest breaking news and headlines.

Tom Llamas anchors the latest news, going beyond the headlines to see how lives are affected by the world around them.

Stay informed with the latest breaking news and headlines.

Sheldon's latest scientific breakthrough leaves him feeling like a fraud; a romantic gesture between Howard and Bernadette causes Penny to up her game with Leonard.

Season 21 lives up to its lucky number with more Golden Buzzers in one night than ever before; it's an evening full of surprises, with a lineup ranging from not one but two dance crews that are not human, to a crossbow stunt duo taking the stage.

Jimmy Fallon and celebrity guest Anthony Anderson pair up with contestants and face off over two games; hosted by Keke Palmer, players must guess secret passwords using only one-word clues for a chance to win up to $25,000.

Stay informed with the latest breaking news and headlines.

Actor Paul Rudd; composer Andrew Lloyd Webber; actor Nicholas Galitzine; comic Ron Taylor.

Actress Anna Faris; singer-songwriter Pink; writer Ann Patchett.

Stay informed with the latest breaking news and headlines.

A daily live broadcast provides current domestic and international news, weather reports and interviews with newsmakers from the worlds of politics, business, media, entertainment and sports. Additionally, specific segments such as Today's Money, Today's Kitchen and Today Throws a Wedding target specific lifestyle issues, and the show's anchors frequently report on special themes from around the g

This early-morning news covers overnight events, breaking domestic and international news as well as a preview of the day's anticipated events. The program also presents regular reports from the worlds of business, entertainment and sports.

This early-morning news covers overnight events, breaking domestic and international news as well as a preview of the day's anticipated events. The program also presents regular reports from the worlds of business, entertainment and sports.

This early-morning news covers overnight events, breaking domestic and international news as well as a preview of the day's anticipated events. The program also presents regular reports from the worlds of business, entertainment and sports.

Stay informed with the latest breaking news and headlines.

Stay informed with the latest breaking news and headlines.

Director Steven Spielberg and actors Emily Blunt, Josh O'Connor and Colman Domingo ("Disclosure Day"); actor Will Forte; Steals and Deals with Jill Martin; style expert Zanna Roberts Rassi.

Fashion expert Jill Martin; actress Camila Mendes; what to watch with Nikki Novak; Today Food with Sunny Anderson.

Social dilemmas; comic Kareem Rahma; surprising perimenopause symptoms with Dr. Sharon Malone; Today Food with Dina Deleasa-Gonsar; author Ann Patchett.

Exploring the challenges and triumphs of aging, and celebrating the wisdom, strength and beauty that come with life's later stages.

Stay informed with the latest breaking news and headlines.

NBC News provides viewers with the latest national and international news; consumer, health and personal finance reporting; up-to-the-minute local news.

Secrets emerge and a family is torn apart when a cop's wife is shot to death in her bed.

The key to "Scrambled Up" is its simple, fast and fun format. Four players compete to be the first to correctly unscramble word puzzles. Colorful tiles slowly rearrange themselves while players are given clues to the answer. Host Michael Yo.

The key to "Scrambled Up" is its simple, fast and fun format. Four players compete to be the first to correctly unscramble word puzzles. Colorful tiles slowly rearrange themselves while players are given clues to the answer. Host Michael Yo.

They're in the right vibe, wrong word -- can they button it up in time, or do they unravel in the final seconds?

Momentum builds, then the team stalls. Can they flip the round back in their favor before the buzzer?

Sheldon goes to extremes to keep Leonard and Penny happy when they stop speaking to each other.

A syndicated news magazine includes investigative reports, interviews with newsmakers, human interest stories and celebrity and pop-culture features.

Stay informed with the latest breaking news and headlines.

Tom Llamas anchors the latest news, going beyond the headlines to see how lives are affected by the world around them.

Stay informed with the latest breaking news and headlines.

When Professor Proton asks Leonard for help with an experiment, Sheldon retaliates by befriending Proton's rival, Bill Nye.

Wolf grapples with being a psych patient at Hudson Oaks and has a startling revelation; a renowned chef comes into Bronx General after a harrowing accident at his restaurant.

A traffic jam forces Violet and Novak to take drastic measures to save a patient; Severide shadows Pascal for a day; Kidd goes the extra mile for Isaiah.

A string of violent robberies across the city digs up one family's secrets; a surprising detail of Voight's past resurfaces.

Stay informed with the latest breaking news and headlines.

Singer Nick Jonas; actress Amy Sedaris; Violet Grohl performs.

Actor Will Forte; actress Alison Brie.