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Karen and Mark Duenas manage to keep the romance alive even after raising five sons, then an ordinary night ends in a tragic murder that will test the bonds of family.

Local and regional news coverage.

Evening news coverage.

Tom Llamas anchors the latest news, going beyond the headlines to see how lives are affected by the world around them.

Evening news.

Stay informed with the latest breaking news and headlines.

The doctors at Gaffney work to save one of their own in critical danger; Hannah finds herself at odds with the ob-gyn who will fill in for her maternity leave.

After a devastating fire erupts at a surgery center, Kidd works to hunt down the true cause; Violet, Novak and Vasquez grapple with shifting relationships; Molly's hosts its first trivia night.

Tensions between Voight and Imani begin to form when a series of ATM robberies hits the city.

Local, national and international news coverage.

Former professional football player Tom Brady; actress Linda Cardellini; professional basketball player Derrick White; comic Katie Boyle.

Actress Annette Bening; comic Robby Hoffman; author Tayari Jones.

Local, national and international news coverage.

Visiting actor Eric Stonestreet on his 78-acre property near Kansas City; Stonestreet recounts his grueling journey to landing his role in ABC's "Modern Family," and how it changed his life.

Learn what's behind mental decline with age, and how to improve memory, focus and concentration with NeuroQ's Darrin Peterson and Dale Bredesen MD.

Reporting of breaking news and developing stories in real time.

This early-morning news covers overnight events, breaking domestic and international news as well as a preview of the day's anticipated events. The program also presents regular reports from the worlds of business, entertainment and sports.

This early-morning news covers overnight events, breaking domestic and international news as well as a preview of the day's anticipated events. The program also presents regular reports from the worlds of business, entertainment and sports.

This early-morning news covers overnight events, breaking domestic and international news as well as a preview of the day's anticipated events. The program also presents regular reports from the worlds of business, entertainment and sports.

Local and regional news coverage.

Local and regional news coverage.

Local and regional news coverage.

Local and regional news coverage.

Navigating drug discounts; actor Matthew MacFadyen; style expert Chassie Post; Today Food with Maggie Baird.

How men and women treat pain with Dr. Akshay Syal and Dr. Natalie Azar; actor John C. Reilly; actor Billy Magnussen; lifestyle expert Sarah Eggenberger; Il Volo performs.

TV personality Daryn Carp; actress Storm Reid; makeovers with Jenna Lyons and Chris Appleton; Today Food with Edy Massih.

Dan Levy and Felicity Huffman are here; it's "Shopping Day at Live" with Monica Mangin; "Spring Has Sprung Week" continues with a special edition of "The Inbox"!

NBC News provides viewers with the latest national and international news; consumer, health and personal finance reporting; up-to-the-minute local news.

Stay informed with the latest breaking news and headlines.

Midday news coverage.

Lurking in the woods and peeping through windows, a cold-blooded serial killer stalks his next victim.

Local and regional news coverage.

Evening news coverage.

Tom Llamas anchors the latest news, going beyond the headlines to see how lives are affected by the world around them.

Evening news.

Stay informed with the latest breaking news and headlines.

Riley and Walker investigate the murder of a beloved museum security guard and the theft of a priceless artifact; Baxter and Price must balance their pursuit of justice with public pressure to return the artifact.

Benson is shocked to find undercover Detective Velasco at the center of a sex trafficking bust; when more women are smuggled into the city, a rescued victim begs SVU to help save her sister.

Haunted by the voice of her dead mortician father, Colette Akins terrorizes the community where she once lived; while new bodies pile up, Bex and the team discover a strange connection that all of Colette's targets share.

Local, national and international news coverage.

Actress Kerry Washington; actor Riz Ahmed; Julia Cumming performs.

Actor Jim Parsons; actress Alana Haim; comic Chris Fleming.

Local, national and international news coverage.

Visiting actor Eric Stonestreet on his 78-acre property near Kansas City; Stonestreet recounts his grueling journey to landing his role in ABC's "Modern Family," and how it changed his life.

Ground and air ambulance bills are higher than ever! Medicare & private insurance may not always cover costs. Imagine getting a bill for thousands of dollars! Protect yourself and let MASA pay ambulance bills your insurance may not.

Reporting of breaking news and developing stories in real time.

This early-morning news covers overnight events, breaking domestic and international news as well as a preview of the day's anticipated events. The program also presents regular reports from the worlds of business, entertainment and sports.

This early-morning news covers overnight events, breaking domestic and international news as well as a preview of the day's anticipated events. The program also presents regular reports from the worlds of business, entertainment and sports.

This early-morning news covers overnight events, breaking domestic and international news as well as a preview of the day's anticipated events. The program also presents regular reports from the worlds of business, entertainment and sports.

Local and regional news coverage.

Local and regional news coverage.

Local and regional news coverage.

Local and regional news coverage.

Journalist Willie Geist; actress Michelle Pfeiffer; fashion expert Melissa Garcia; actress Elizabeth Banks.

Dermatology facts with Dr. Angela Lamb; actress Elizabeth Banks; TV personality Lo Bosworth; what to read with Harlan Coben; Today Food with Bill Peet.

Social dilemmas; actress Rachel Dratch; spring hacks with Babs Costello; Anne Mahlum, Solidcore founder; Bobbie's Bests.

Eva Longoria drops by the studio; Regé-Jean Page is here; "Spring Has Sprung Week" concludes with spring gardening ideas!

NBC News provides viewers with the latest national and international news; consumer, health and personal finance reporting; up-to-the-minute local news.

Stay informed with the latest breaking news and headlines.

Midday news coverage.

Conversation with the candidates.

Mischele Lewis' new boyfriend seems almost too good to be true, then she discovers he is a con man harboring dark secrets and embarks on a dangerous mission to expose him.

Local and regional news coverage.

Evening news coverage.

Tom Llamas anchors the latest news, going beyond the headlines to see how lives are affected by the world around them.

Evening news.

Stay informed with the latest breaking news and headlines.

When Bobbie struggles to find the perfect buyers for Happy's house, Gabby has the solution and thinks of her mother, Val; Steve convinces Emmett that he should be dressing much nicer for his upcoming date with Monica.

After being fired from her beloved role as head coach of a first-class cheerleading team, Courteney Potter is ready to stage the ultimate comeback. Just one championship shy of becoming the winningest college cheer coach ever, she takes a new job in a small Southern town where she recruits a group of lovable misfits in the hopes of training them to become a competitive squad. But getting this coll

Anchored by Lester Holt, "Dateline" is NBC's signature newsmagazine, bringing viewers storytelling at its best by putting the pieces together to present the full picture of real-life events. NBC News correspondents cover compelling stories and issues of the day, ranging from mystery and crime to in-depth investigations and breaking-news events.