KHNL-DT

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Danielle and Dr. Pablo discuss how cancer develops, why early detection matters and new screening tools; by connecting past stories with present science, Dr. Pablo questions whether cancer can be caught before it ever has a chance to take hold.

A man says he's still owed money for a "skidsteer," while his former friend argues that he got stuck with a machine that belongs in the scrapyard.

A buyer says he was left dead in the water after purchasing a boat engine that wouldn't fire up; the seller argues that the sale was "as-is" and says the buyer sank any refund hopes by dismantling the motor; it's left to the judges to decide who's charting the truth and who's drifting off course.

A woman and her boyfriend accuse each other of assault; ex-lovers feud over $1,000.

Stay informed with the latest breaking news and headlines.

Stay informed with the latest breaking news and headlines.

Local, national and international news.

Local, national and international news.

Tom Llamas anchors the latest news, going beyond the headlines to see how lives are affected by the world around them.

Stay informed with the latest breaking news and headlines.

A bank heist turns deadly as the U.S. Marshals and FBI clash to bring down the fugitive, pitting Jane against Clare; Micah adjusts to working for Mike on the Secret Service while hiding a forbidden relationship.

Anchored by Lester Holt, "Dateline" is NBC's signature newsmagazine, bringing viewers storytelling at its best by putting the pieces together to present the full picture of real-life events. NBC News correspondents cover compelling stories and issues of the day, ranging from mystery and crime to in-depth investigations and breaking-news events.

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TV host Conan O'Brien; Brandon Flowers talks and performs; actress Lauren Lapkus.

Actor Jon Hamm; actress Sabrina Impacciatore; comic Taylor Tomlinson.

Tom Llamas anchors the latest news, going beyond the headlines to see how lives are affected by the world around them.

Stay informed with the latest breaking news and headlines.

The weekday news magazine takes an in-depth look at topics from politics to personal finance, featuring watchdog reports about government corruption and failures, consumer alerts and health care issues.

Reporting of breaking news and developing stories in real time.

The 2025-26 New York Knicks end a 53-year championship drought, igniting a healing outpouring of joy across the five boroughs and the entire nation.

Johnny Bananas explores South Florida by going iguana hunting, visiting the haunted Deering Estate and checking out Jungle Island.

Tabitha Lipkin uncovers a hidden world of alpine wine, giant puppets and handcrafted food and art in Vermont.

Tamsen Fadal interviews celebrities, rising stars and special guests from Broadway to off-Broadway.

News headlines, interviews, and stories intended to inform, entertain, inspire and set the agenda each morning for Americans and help viewers with their finances, health and well-being.

From Road Atlanta in Braselton, Ga.

Following all the action from the world of horse racing.

Paid programming.

Tom Llamas anchors the latest news, going beyond the headlines to see how lives are affected by the world around them.

Preseason breakdown of Big Ten football team expectations.

From Los Angeles Memorial Coliseum in Los Angeles.

Local, national and international news.

An in-depth look at topics from politics to personal finance, featuring watchdog reports about government corruption and failures, consumer alerts and health care issues.

Highlighting inspiring people who are making a difference across America.

Host Dakota Johnson; Turnstile performs.

A traveling outdoor grilling show, filled with humor, food and fun; self-proclaimed "grillologists" Mad Dog and Merrill host.

A traveling outdoor grilling show, filled with humor, food and fun; self-proclaimed "grillologists" Mad Dog and Merrill host.

Stay informed with the latest breaking news and headlines.

Host Dakota Johnson; Turnstile performs.

Tamsen Fadal interviews celebrities, rising stars and special guests from Broadway to off-Broadway.

Star athletes talk about the influences and motivating factors behind their success.

Stay informed with the latest breaking news and headlines.

Mike has trouble finding a Christmas gift for Ed; Eve returns to visit; Vanessa helps the family realize the importance of its long-standing holiday family traditions.

Boyd insists he, Mike and Ryan take a trip together, forcing the men to get along; Mandy and Kyle pretend to be detectives when they suspect Ed was involved in a long-ago murder.

The Dunphys travel to New York, while Mitch, Cam and Lily visit the Midwest, and Jay, Gloria, Manny and Joe go to Mexico; the family gets together for Father's Day.

Jay wants to make a good impression on a family moving in across the street; Manny tries to attract a radical thinker; the Dunphy family uses Alex's bout of mono to its advantage; Cam and Mitchell try to teach a message of acceptance.

Reality-TV star Bozoma Saint John and fiancée Keely Watson kick off their fiancée-moon in Belgium, curated by competing luxury travel advisers June Kleier and Julie Shotmeyer of Global Travel Collection.

An empowering transformation for an ALS fighter and her family.

Turning a beloved teacher's fixer-upper into a forever home.

Sharp conversational coverage of the week's news, along with in-depth profiles of the people and personalities shaping American culture, assessing the highs and lows of the week and looking ahead to the next one.

Interviews with public figures and those making news, setting the political agenda and spotlighting the impact Washington decision-making has on Americans.

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Paid programming.

Women's basketball experts weigh-in on the upcoming WNBA game.

All the latest basketball action from the WNBA.

Paid programming.

Tom Llamas anchors the latest news, going beyond the headlines to see how lives are affected by the world around them.

"Football Night in America" features host Maria Taylor, former NFL head coach and quarterback Jason Garrett, former NFL head coach Mike Tomlin and NFL insider Mike Florio recapping the day's NFL highlights.

The Detroit Lions clash with the Carolina Panthers in Week 4 at Bank of America stadium. Detroit enters following a 31-24 win over the Jets on September 27, while host Carolina aims to bounce back from a 21-18 loss to Cleveland the same day.

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Host Christian Stevenson aka "DJ BBQ" explores unique and up-and-coming places across America.

Showcasing Japan's unique foods, rich history, scenic locales and people in a virtual journey across Japan.