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Penny worries that she's screwed things up with her friends after her night with Raj. Sheldon takes command of the paintball team.

Amy is stuck in the middle of a battle of wills between Penny and Sheldon. Leonard and Priya try to spice up their long-distance relationship.

Leonard goes to a colleague's wedding as Amy's date. Howard tries to convince Bernadette to live with his mum after they get married.

Raj begins to get upset that he's the only one of the four guys not in a relationship, so Penny sets out to find him the perfect date.

Sheldon's old nemesis Wil Wheaton returns and invites everyone to a housewarming party. But Sheldon threatens to 'de-friend' Leonard if he attends.

Sheldon's mother Mary comes to town and soon becomes a firm favourite with his friends, much to Sheldon's annoyance.

Leonard doubts his feelings for Priya when he kisses a woman he meets in the comic book shop. The gang pull pranks on Sheldon to celebrate Halloween.

Amy is heartbroken when she finds out that Penny and Bernadette went on a shopping trip to buy bridesmaids' dresses without her.

Leonard and Penny attempt to spend time together as friends without anybody else around, while Sheldon faces his fear of birds.

Stuart from the comic book shop invites Amy out on a date. Consumed by jealousy, Sheldon then asks her to be his girlfriend.

Leonard confronts the man who bullied him in high school, while Penny realises that she did her fair share of tormenting in the past.

When Sheldon is dismissive of Amy's career, Penny, Raj and Leonard teach him that sometimes it's a good idea to pretend to care about things.

In the 100th episode of the US sitcom, Leonard and Penny agree to give their relationship another chance, but they soon start to argue again.

Leonard and Penny put their relationship through a 'beta test' and report problems with each other as 'bugs'. Sheldon and Amy seek internet fame.

After Sheldon keeps him awake all night, an irate Leonard decides he needs to break the roommate agreement, which formally ends their friendship.

Sheldon helps Amy in her biology lab after he is forced to use up two weeks of holiday, but he is bored by the tasks that she gives him.

Sheldon and Kripke argue over who should get Professor Rothman's vacant corner office. Amy buys Penny some art to celebrate their friendship.

Sheldon's well-organised world is turned upside down when he learns that the barber who has cut his hair for years is ill in hospital.

Amy is upset when Sheldon breaks his promise to attend her aunt's birthday party in order to join the guys for a Star Wars video game marathon instead.

Penny buys Leonard and Sheldon some Star Trek memorabilia, but she is irked when they refuse to remove the toys from their packaging.

When Stephen Hawking comes to lecture at the university, Howard is given the task of maintaining his wheelchair, which makes Sheldon envious.

Leonard, Sheldon and Raj throw a bachelor party for Howard, during which some stories about his sexual history are accidentally revealed.

When NASA inform Howard that his space mission has been rescheduled to an earlier date, he tries to use the wedding as an excuse not to go.

Bernadette decides that she wants to get married to Howard before his NASA space mission, but can they get organised in time.

When Marge breaks her leg in a skiing accident, Lisa takes over running the Simpson household, and Homer and Bart end up moving to a leper colony in Hawaii.

How I Spent My Strummer Vacation: Homer goes to a rock 'n' roll camp. When it's time to leave, he just wants to keep rockin' with Mick Jagger, Keith Richards and Lenny Kravitz.

for Stand Up To Cancer: Kelly Brook, Mo Gilligan, Carol Vorderman and Rob Rinder tackle signature sandwich biscuits, iced buns, and a cake showstopper revealing their guilty pleasure.

Things get spicy for host Jimmy Carr and a roster of comedy rivals, including Michael McIntyre, Davina McCall and Lee Mack, in an episode celebrating rivalry on the Big Fat Quiz.

Winning Connections: It's the final, and the final three couples set about proving their connections - and disproving others' - to win the £50,000 prize.

Nicola's been divorced twice but is still young at heart and hopes for a new love. Mark, who has Crohn's disease, has lost his body confidence but is now ready to conquer his fear.