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A high-school sophomore goes missing in the Season 4 premiere. (Repeat).

An Albuquerque woman is murdered in her own home. (Repeat).

The murder of an 18-year-old California woman is investigated. (Repeat).

A man is found dead of a gunshot wound in his apartment, and suspicion falls on the victim's fiancée, who disappeared after the attack. (Repeat).

A couple are murdered in an idyllic Texas town. (Repeat).

A Maryland man is killed the day before Thanksgiving. (Repeat).

One warm summer afternoon, the town of Verona, Wisconsin, faced its first triple homicide. To solve the case, investigators had to delve into the world of high rollers and offshore betting. (Repeat).

An unidentified body is found on a rural California road and investigators find clues in a tire tread and a broken piece of jewelry. (Repeat).

A hit-and-run in Harrisburg, Pa., is investigated, as police try to find the owner of the vehicle used in the crime. (Repeat).

Investigators disagree with a medical examiner's report on a person's death. (Repeat).

A man dies in a hit-and-run boating incident, and a witness comes forward during the investigation who claims to have been in the fleeing boat. (Repeat).

A woman was found dead on the bedroom floor of her apartment. The crime scene yielded little of value, and investigators wondered if they would find enough evidence to make a case, much less catch a killer. But a bloodstained sheet and a breakthrough forensic technique enabled them to identify the murderer, and convince the jury of his guilt. (Repeat).

The apparent accidental death of a man is probed by authorities, including an arson investigator and a forensic computer expert. (Repeat).

When a woman went missing, friends and family were determined to find her. Their worst fears were confirmed weeks later when her body was discovered. Blood evidence and computer forensics helped investigators to catch the killer, and convince the jury of his guilt. (Repeat).

In 1993, 82-year-old Kathryn Bishop was found dead in her Pennsylvania home. The evidence at the scene indicated that the perpetrator had been running out of the house, not breaking into it. Tiny clues on the victim's body would tell police what happened that night, and who was responsible. (Repeat).

The 1998 murder of oil executive Ronald Shaw is recalled. Shaw was killed after three gunmen approached him and his wife, Rosana, and tried to gain access to Shaw's safe. Ronald J. Benson, Reginald P. Basile and Shannon Touchet were convicted for their roles in the killing. (Repeat).

The case of William Joe Jarvis, who was convicted of murdering his wife with a pipe bomb in a box resembling a Christmas present. (Repeat).

The police question a woman's claim that she was abducted; then physical evidence emerges that could confirm her story. (Repeat).

One warm summer afternoon, the town of Verona, Wisconsin, faced its first triple homicide. To solve the case, investigators had to delve into the world of high rollers and offshore betting. (Repeat).

An unidentified body is found on a rural California road and investigators find clues in a tire tread and a broken piece of jewelry. (Repeat).

A hit-and-run in Harrisburg, Pa., is investigated, as police try to find the owner of the vehicle used in the crime. (Repeat).

Investigators disagree with a medical examiner's report on a person's death. (Repeat).

A man dies in a hit-and-run boating incident, and a witness comes forward during the investigation who claims to have been in the fleeing boat. (Repeat).

A woman was found dead on the bedroom floor of her apartment. The crime scene yielded little of value, and investigators wondered if they would find enough evidence to make a case, much less catch a killer. But a bloodstained sheet and a breakthrough forensic technique enabled them to identify the murderer, and convince the jury of his guilt. (Repeat).

The apparent accidental death of a man is probed by authorities, including an arson investigator and a forensic computer expert. (Repeat).

When a woman went missing, friends and family were determined to find her. Their worst fears were confirmed weeks later when her body was discovered. Blood evidence and computer forensics helped investigators to catch the killer, and convince the jury of his guilt. (Repeat).

In 1993, 82-year-old Kathryn Bishop was found dead in her Pennsylvania home. The evidence at the scene indicated that the perpetrator had been running out of the house, not breaking into it. Tiny clues on the victim's body would tell police what happened that night, and who was responsible. (Repeat).

The 1998 murder of oil executive Ronald Shaw is recalled. Shaw was killed after three gunmen approached him and his wife, Rosana, and tried to gain access to Shaw's safe. Ronald J. Benson, Reginald P. Basile and Shannon Touchet were convicted for their roles in the killing. (Repeat).

The case of William Joe Jarvis, who was convicted of murdering his wife with a pipe bomb in a box resembling a Christmas present. (Repeat).

The police question a woman's claim that she was abducted; then physical evidence emerges that could confirm her story. (Repeat).

A young single mother is abducted from a gas station and later found stabbed to death near an oil field. Detectives use shoe and tire impressions to weed out numerous suspects and find their killer. (Repeat).

When a 23-year-old Marine dies in his bedroom, doctors initially believe a heart attack is to blame, but when arsenic is found in his organs, his wife is charged with murder. A sharp attorney and toxicological testing uncover the truth. (Repeat).

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A Tennessee woman is murdered in the woods behind her home. (Repeat).

A Wyoming teenager goes missing. (Repeat).

A Wisconsin salesman is stabbed to death. (Repeat).

A teenager goes missing in upstate New York. (Repeat).

A 22-year-old Pennsylvania artist disappears. (Repeat).

A Pennsylvania woman is found shot to death inside her basement. (Repeat).

A woman disappears without a trace in Mississippi. (Repeat).

A triple murder in Lancaster, Pa., is investigated. (Repeat).

Blood-spatter experts and a forensic meteorologist try to determine whether the death of a man's wife was accidental. (Repeat).

The death of a police lieutenant's wife is investigated, and a short audio tape found by the police helps solve the case. (Repeat).

The victim had ingested a massive amount of cyanide. An unlikely clue – a flaw on a mailing envelope – exposed a murderer who was willing to kill innocent (Repeat).

Two young people are found dead, and their house burns down. (Repeat).