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Sheldon and Amy subject their friends to a series of experiments to choose the best man and maid of honour. And Penny reveals her true feelings.

Amy and Leonard bond during a series of experiments. Bert replaces Howard in Footprints on the Moon, and Sheldon finds Penny a source of inspiration.

Raj learns the woman he's dating has a very upset husband. Sheldon rents his old room for a quiet place to work.

After only one of the twins qualifies for surgery, they face a tough decision: move forward alone or fail together.

Nefi. At 25 years old and weighing in at 626 pounds, Nefi seeks Dr. Now's help. But he must change his relationship with his mum to succeed.

Ed, Richard and Joanne back more wild ideas. Guz has to lay into his hometown Coventry, Maisie tackles AI, and Chris takes on an Olympic legend.

Tim has a massive growth on his back that affects his ability to work and socialise. Meanwhile, a mother-daughter duo has bonded over their bumps.

Rhonda has bumps all over her head, including a worrying horned growth. And, Dr. Lee treats Kevin, who has a huge lump protruding from his hip.

At 605-lbs, Tracey carries most of her body weight in her misshapen legs, which are so extreme she needs someone to lift them out of bed. Can Dr. Nowzaradan help her.

Kirsty wants to wear trousers on her big day, so Gok gets creative with his designs. Celise is worried her Mormon parents won't approve of her dress.

A priest wants a smooth outfit for her wedding day in Sicily. Plus, Rachel is concerned her recent weight gain will hamper her search for a dress.

Georgie worries he's letting his family down when he's forced to stay home ill, and Mandy worries about how her career will affect her marriage.

Jim feels ganged up on when Georgie and Audrey make changes to the tire store, and Mandy helps Georgie navigate a fight between her parents.

When George Sr. is rushed to the emergency room, Meemaw comes to babysit. And the kids have an adventure getting to the hospital on their own.

Sheldon refuses to eat solid food after a choking scare but finds solace in a new interest after he discovers comic books.

A Solar Calculator, A Game Ball. Sheldon uses his statistics skills to help his father coach the football team. Both Sheldon and Georgie struggle with the popularity this brings.

A Patch, A Modem And A Zantac. After being dismissed in class, Sheldon is determined to prove a visiting NASA representative wrong and starts studying theoretical physics.

Sheldon and Bert collaborate on a research project, while Penny and Bernadette coach Koothrappali on how to navigate his relationship with Ruchi.

Leonard and Howard learn Sheldon went to work with the military. Bernadette suspects Ruchi is trying to steal her job.

The guys cut Sheldon out of a potentially valuable Bitcoin investment. Also, an old video reveals a secret about Leonard and Penny's relationship.

Sheldon and Amy try to eliminate stress from wedding planning using maths. Raj realises his best friend is actually hurting his confidence.

Sheldon and Howard plan birthday celebrations for Amy and Halley. Leonard spirals out about his lack of accomplishments.

Sheldon and Amy subject their friends to a series of experiments to choose the best man and maid of honour. And Penny reveals her true feelings.

Amy and Leonard bond during a series of experiments. Bert replaces Howard in Footprints on the Moon, and Sheldon finds Penny a source of inspiration.

Raj learns the woman he's dating has a very upset husband. Sheldon rents his old room for a quiet place to work.

Mandy finds out Meemaw runs an illegal sportsbook and wants in on the action. Meanwhile, Georgie struggles to keep Mandy's new job a secret.

Georgie helps Connor impress his new crush, while Mandy, Audrey and Jim struggle to butt out of Connor's love life.

A Brisket, Voodoo And Cannonball Run. Meemaw refuses to give George Sr. her brisket recipe. The kids try to think of ways to resolve this family feud.

George takes his sons to see a space shuttle launch. Meanwhile, Mary, Meemaw and Missy have a girl's night at the salon.

George Sr. makes a deal with Sheldon to tutor his brother when Georgie's poor grades threaten his place on the football team.

Sheldon interviews with a school for gifted children. Much to their surprise, the rest of the family struggle with his absence.

Wil Wheaton offers Amy a role on the new 'Professor Proton Show,' and Penny thinks the female protagonist in Leonard's novel is based on her.

All Bernadette's friends try different tactics to get labour started. Amy accidentally reveals she's already chosen their son's name.

Leonard tries to secure the perfect wedding venue for Sheldon and Amy. Bernadette and Howard have a hard time deciding who should go back to work.

Bill Gates' company wants to partner with Penny's pharmaceutical company. Leonard, Raj and Howard do everything in their power to meet him.

Leonard decides to run against Sheldon for president of the tenants' association. Bernadette encourages Howard and Raj to find the owner of a drone.

A reclusive scientist invites Sheldon to his remote cabin. Penny and Bernadette improvise after Amy doesn't like the bachelorette they planned.

Sheldon's comic book store experience changes when Neil Gaiman puts Stuart's store on the map. And Raj takes credit for Penny's astronomical discovery.

Sheldon goes to Vegas to win money for science. Penny and Bernadette take Amy wedding dress shopping, but her choice entangles them in a web of lies.

L.A. will never be the same after brash Detroit cop Axel hits town. He turns Beverly Hills upside-down and teaches the local police a thing or two.

Ed, Richard and Joanne back more wild ideas. Guz has to lay into his hometown Coventry, Maisie tackles AI, and Chris takes on an Olympic legend.

Gerald returns to see Dr. Lee and a hand specialist about a huge, intrusive bump on his finger. Vinnie has an embarrassing birthmark on his neck.

David is back to see Dr. Lee after she spotted a suspicious growth under his eye. And, Alan has a growth on his bicep but is terrified of doctors.

Steven And Justin's Story Part 1. Steven weighs 800-lbs and his brother, Justin, 600-lbs. Desperate to save both his sons' lives, their father travels across the US to seek help.

Nikki has a budget of £5,000 to find the perfect dress for her big day. Plus, Lisa seeks a unique outfit that will make her stand out on social media.

After losing six stone, Steph is nervous about finding a dress that suits her figure. Plus, Gok helps Esther pick out an outfit with a budget of £3,000.

Mandy finds out Meemaw runs an illegal sportsbook and wants in on the action. Meanwhile, Georgie struggles to keep Mandy's new job a secret.

Georgie helps Connor impress his new crush, while Mandy, Audrey and Jim struggle to butt out of Connor's love life.

A Brisket, Voodoo And Cannonball Run. Meemaw refuses to give George Sr. her brisket recipe. The kids try to think of ways to resolve this family feud.

George takes his sons to see a space shuttle launch. Meanwhile, Mary, Meemaw and Missy have a girl's night at the salon.

George Sr. makes a deal with Sheldon to tutor his brother when Georgie's poor grades threaten his place on the football team.

Sheldon interviews with a school for gifted children. Much to their surprise, the rest of the family struggle with his absence.

Wil Wheaton offers Amy a role on the new 'Professor Proton Show,' and Penny thinks the female protagonist in Leonard's novel is based on her.

All Bernadette's friends try different tactics to get labour started. Amy accidentally reveals she's already chosen their son's name.

Leonard tries to secure the perfect wedding venue for Sheldon and Amy. Bernadette and Howard have a hard time deciding who should go back to work.

Bill Gates' company wants to partner with Penny's pharmaceutical company. Leonard, Raj and Howard do everything in their power to meet him.

Leonard decides to run against Sheldon for president of the tenants' association. Bernadette encourages Howard and Raj to find the owner of a drone.

A reclusive scientist invites Sheldon to his remote cabin. Penny and Bernadette improvise after Amy doesn't like the bachelorette they planned.

Sheldon's comic book store experience changes when Neil Gaiman puts Stuart's store on the map. And Raj takes credit for Penny's astronomical discovery.

Sheldon goes to Vegas to win money for science. Penny and Bernadette take Amy wedding dress shopping, but her choice entangles them in a web of lies.

Baby Fight! Georgie and Mandy worry they're not on the same page when they disagree about having another kid, and Mary, Jim and Audrey struggle to stay out of it.

Two Idiots On A Dirt Bike. Georgie's attempt to break up Missy and her new boyfriend backfires, with severe consequences.

A worried Mary sends Sheldon to Sunday school after she finds him playing Dungeons & Dragons with Tam and Billy.

Sheldon asking for a computer has unforeseen consequences for his parents, prompting Mary and the twins to move in with Meemaw.

Sheldon's germophobia lands him in detention when flu season hits Medford and he takes extreme measures to remain healthy.

When Mary takes a job at the church, Sheldon and Missy are left home alone for the very first time.

Sheldon and Leonard travel to Texas to end a family feud. The Wolowitz kids inadvertently infest Amy, Bernadette, Howard and Raj with pinkeye.

When Amy's parents and Sheldon's family arrive, everybody is focused on making sure all goes according to plan - everyone except the bride and groom.

Sheldon and Amy's honeymoon runs aground, while Penny and Leonard discover similarities with Amy's parents. Raj insults physicist Neil deGrasse Tyson.

Sheldon and Amy try to figure out what 'perfect gift' Leonard and Penny gave them. Raj asks his father to arrange a marriage for him.

Stuart starts bringing his new girlfriend home, Penny and Leonard talk about starting a family, and Raj explores an arranged marriage.

Sheldon won't tell anyone why he's never mentioned his childhood friend Tam. Bernadette and Penny take out Raj's fiancée to get the skinny on her.

Amy doesn't have time to work on a project, so Sheldon goes to great lengths to ensure she can work with him, even if it means sabotaging her career.

When Howard dresses up as Sheldon for Halloween, Sheldon seeks retaliation. Leonard is shocked that Penny doesn't remember their first kiss.

Catie and Josh argue over finances. A Halloween fiasco leads to drama between Debby and Mido, while Edward attempts to bond with Marissa's kids.

Matt has a skin condition that causes tumours to grow all over his body. Plus, Jennifer has a unicorn bump on her forehead.

Dennis has several giant growths on his head. Juan has a rare condition he hopes Dr. Lee will understand. Natalie is covered in hundreds of mysterious dark bumps.

Former cruise ship worker Julie hopes Dr. Lee can remove her large back growth. And, JD is a gentle giant with a pear-shaped mass hanging off his ear.

Steven And Justin's Story Part 2. After a year on a weight loss programme, Steven is non-compliant, and Justin focuses on a new career instead of his diet. Time is running out.

60-year-old Wendy refuses to be defined by her age and wants a revealing showstopper gown. Plus, Amy has fallen out of love with her dream dress.

Hannah is no longer sure she wants the huge princess gown she dreamed of as a child. And, Lisa turns up to the boutique with her fiancé.

Sheldon gets an odd request from an old friend, while George and Mary are caught in the middle of Meemaw and Dale's breakup.

While Sheldon copes with the death of a hero, Georgie struggles with his big secret, and Missy wants to babysit.

George and Mary insist on meeting the new woman in Georgie's life, while Sheldon and Missy have suspicions about what's going on with their family.

Despite the whole family trying to keep it a secret, Sheldon and Missy learn about Georgie's pregnancy.

With the Coopers facing judgement from the congregation in the wake of Georgie's pregnancy, Sheldon is distracted by the family drama.

Sheldon struggles with the first signs of puberty while his parents hunt for new jobs, and Georgie and Meemaw take a business trip across the border.

Nine-year-old Sheldon learns that his high intelligence isn't always helpful growing up in East Texas, where church and football are king.

To appease his worried mother, Sheldon employs the techniques of a self-help book to try and make a friend.

Leonard and Howard engineer a distraction for Sheldon to keep him from hindering progress on the guidance-system project.

Amy is incensed when she learns Sheldon has shared intimate relationship information, and Raj's father stops sending financial support.

Raj finds himself in a cash crunch and turns to Sheldon to help him. Meanwhile, Penny considers crashing the guys' annual Comic-Con getaway.

Leonard and Penny offer Sheldon's old room to Raj after he moves out of his apartment.

Raj moves in with Leonard and Penny, and a period of adjustment begins, while usually self-centred Sheldon shows surprising interest in Amy's work.

Sheldon is pushing himself with too many collaborations. Bernadette's maternity leave is running out, and she must face going back to work.

Leaving the baby in daycare proves to be tough for Bernadette, and geologist Bert digs up a girlfriend, but some colleagues think she's a gold digger.

Leonard isn't thrilled when Penny considers taking a new job offered by her ex-boyfriend, Zack.

Leonard, Sheldon and Wolowitz celebrate the completion of their top-secret military project, until an unpleasant surprise leaves their heads spinning.

Sheldon's former admirer, Dr. Ramona Nowitzki, turns up while Amy is visiting Princeton, and the gang is extremely concerned.

What did she say? Amy answers Sheldon's marriage proposal. Meanwhile, Howard and Bernadette struggle with some unexpected news.

Leonard's job is at stake when he gives an embarrassing radio interview which angers the university and the entire physics community.

Amy tries to convince Sheldon that he has a more laid-back side, meanwhile, Raj and Stuart compete to win the heart of Bernadette's new co-worker.

Wolowitz and Sheldon bond over their relationships with their disappointing fathers. And Leonard's mum finds a new best friend in Penny.

Sheldon and Raj confide in Bernadette when they can't handle Amy and Howard working together. Penny and Leonard learn new ways to deal with Sheldon.

Sheldon goes head-to-head with Wil Wheaton. Penny takes care of Halley when Bernadette and Howard are both on bed rest.

Sheldon and Bert collaborate on a research project, while Penny and Bernadette coach Koothrappali on how to navigate his relationship with Ruchi.

Leonard and Howard learn Sheldon went to work with the military. Bernadette suspects Ruchi is trying to steal her job.

The guys cut Sheldon out of a potentially valuable Bitcoin investment. Also, an old video reveals a secret about Leonard and Penny's relationship.

Sheldon and Amy try to eliminate stress from wedding planning using maths. Raj realises his best friend is actually hurting his confidence.

Dr. Lee meets Stephanie, who has a giant baseball-sized scalp bump. Plus, Wesley believes that a pencil lead is embedded in his palm.

John would love to date but is embarrassed about a huge bump on his cheek. Denise sees Dr. Lee about a growth on her booty.

Allie's polyamorous lifestyle is ruined by the gumball-sized bump above her eye. Later, Dr. Lee treats a patient with a shoulder lipoma.