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Sheldon fears his major scientific breakthrough may haunt him for the rest of his career. Howard makes a grand romantic gesture to Bernadette.

When Sheldon's childhood hero, Professor Proton, seeks Leonard's help with an experiment, Sheldon decides to befriend another TV science guy.

Leonard fails to stop Sheldon from overreacting after a past slight comes to light, and Penny has a run-in with Raj's former girlfriend Lucy.

Howard's mother has a say when he and Bernadette host Thanksgiving dinner for the gang. Penny and Leonard must deal with a mistake from her past.

Georgie helps Connor impress his new crush, while Mandy, Audrey and Jim struggle to butt out of Connor's love life.

Baby Fight! Georgie and Mandy worry they're not on the same page when they disagree about having another kid, and Mary, Jim and Audrey struggle to stay out of it.

Dara Ó Briain presents the final summer special featuring unseen material, out-takes and best bits from the past few weeks.

Ed Gamble hosts as comedians defend unacceptable opinions: Vittorio Angelone on a misunderstood Trump and Fatiha El-Ghorri backing arranged marriage.

Dara Ó Briain presents the final summer special featuring unseen material, out-takes and best bits from the past few weeks.

Sheldon and Missy both run away from home, while Mary gets some upsetting news about her husband, George.

Nhan has an extremely red birthmark that covers half of his face. Debbie worries that her shoulder lump will prematurely age her.

Jess is looking for love but has a giant bump on his neck. Former NFL defensive tackle, Marcell Dareus, hopes Dr. Lee can tackle his forehead lipoma.

Nesrin wants a mermaid-style gown, but her sister hates everything she's tried on. Jennifer races the clock to find a frock, but her sister gets entourage fatigue.

Having spent the last two years in his bed due to his weight, Cillas' food addiction prevents him from being there for his fiancée and her three daughters.

Randy Will Show You The Door. Bridal model Jessica brings her outspoken clique with her to Kleinfeld's, but Randy threatens to kick them out. Plus, Marlo returns with her frank twin.

When Axl is suspended for skipping school, Mike decides it's time to teach his son a life lesson and makes him go to work with him at the quarry.

Frankie's best laid plans go awry when she convinces Mike and the kids that the Heck family should host a foreign exchange student from Japan.

Excited over being invited to the neighbourhood Halloween party, Frankie encourages Mike to dress up in costume.

The Coopers discuss the possibilities of black holes and alternate universes when Dr. Sturgis comes over for dinner.

Missy's first heartbreak triggers a series of events that lead the Cooper family to the brink.

Sheldon and Missy both run away from home, while Mary gets some upsetting news about her husband, George.

Leonard returns from his expedition and finds things chilly between him and Sheldon, and Howard faces questions about his masculinity.

Raj puts together a scientific scavenger hunt that turns into serious, cutthroat competition that brings out the best - and the worst - in the gang.

Amy ruins one of Sheldon's favourite films. Leonard discovers how to get Penny to do his bidding. Raj and Stuart get creative with dating profiles.

Amy takes a job at Sheldon's university, putting their relationship to the test. Howard ends up sleeping on Raj's couch after a fight with Bernadette.

Sheldon fears his major scientific breakthrough may haunt him for the rest of his career. Howard makes a grand romantic gesture to Bernadette.

When Sheldon's childhood hero, Professor Proton, seeks Leonard's help with an experiment, Sheldon decides to befriend another TV science guy.

Leonard fails to stop Sheldon from overreacting after a past slight comes to light, and Penny has a run-in with Raj's former girlfriend Lucy.

Howard's mother has a say when he and Bernadette host Thanksgiving dinner for the gang. Penny and Leonard must deal with a mistake from her past.

Brick demands to hear the true story about the day he was born, a family secret. Axl is confused by his attractive but incompetent new manager.

Brick is sick and tired of being forced to accompany Frankie on her weekend errands and pleads with her to let him stay home alone.

Mike begrudgingly invites his brother Rusty and his father Big Mike, who has recently broken his hip, to join him for the annual family Thanksgiving.

Sheldon encourages Missy to question the Bible. Meemaw determines to catch George Sr. in a lie, and Mary helps Pastor Jeff search for a youth pastor.

While Sheldon tries to convince Dr. Sturgis to return to the university, Georgie upsets the family when he makes a life-changing decision.

Pish Posh And A Secret Room. While Meemaw opens a secret gambling room, Sheldon, Missy and Georgie adapt to new living arrangements.

Amy and Leonard try to help Sheldon when his accidental scientific discovery is disproved. Howard and Bernadette open their home to Raj for a week.

With Sheldon in Texas, the gang decorates for Christmas, and they each contemplate if they would have had a wonderful life if they'd never met him.

Penny turns to Leonard after her guest appearance doesn't turn out well. Sheldon works on his sense of humour, and Raj practices talking to girls.

Penny makes a big step toward pursuing a full-time acting career, and Sheldon is forced to take a vacation.

Unable to score tickets for Comic-Con, Sheldon decides to stage his own comic-book convention, while the ladies attempt to act like grown-ups.

Amy talks Sheldon into a romantic Valentine's Day getaway to Napa Valley. Leonard and Penny make an emergency visit to the vet with Raj's dog.

Leonard's purchase of a new dining room table doesn't sit well with Sheldon, and Bernadette isn't happy about Howard taking another trip to space.

Things turn rocky between Sheldon and Wolowitz, and Bernadette steps in to mediate. Penny is offered a movie role that may prove embarrassing.

Dara Ó Briain presents the final summer special featuring unseen material, out-takes and best bits from the past few weeks.

The evil Decepticons regroup with a new plan to destroy the world. It's up to college student Sam to help Optimus Prime and the Autobots save the day.

Brick demands to hear the true story about the day he was born, a family secret. Axl is confused by his attractive but incompetent new manager.

Brick is sick and tired of being forced to accompany Frankie on her weekend errands and pleads with her to let him stay home alone.

Mike begrudgingly invites his brother Rusty and his father Big Mike, who has recently broken his hip, to join him for the annual family Thanksgiving.

Brent has a tricep bump that could be intertwined in his muscle. Plus, Jeb avoids the beach because of the massive number of bumps all over his body.

With severe lymphedema Mercedes can barely stand, and her family helps her care for her young kids. To successfully lose weight she must confront her past trauma.

Fussy bride Katie has fruitlessly tried on countless dresses and Antonia has a long list of what she doesn't want on a wedding dress. Can David and Danielle deliver.

Brick demands to hear the true story about the day he was born, a family secret. Axl is confused by his attractive but incompetent new manager.

Brick is sick and tired of being forced to accompany Frankie on her weekend errands and pleads with her to let him stay home alone.

Mike begrudgingly invites his brother Rusty and his father Big Mike, who has recently broken his hip, to join him for the annual family Thanksgiving.

Sheldon encourages Missy to question the Bible. Meemaw determines to catch George Sr. in a lie, and Mary helps Pastor Jeff search for a youth pastor.

While Sheldon tries to convince Dr. Sturgis to return to the university, Georgie upsets the family when he makes a life-changing decision.

Pish Posh And A Secret Room. While Meemaw opens a secret gambling room, Sheldon, Missy and Georgie adapt to new living arrangements.

Amy and Leonard try to help Sheldon when his accidental scientific discovery is disproved. Howard and Bernadette open their home to Raj for a week.

With Sheldon in Texas, the gang decorates for Christmas, and they each contemplate if they would have had a wonderful life if they'd never met him.

Penny turns to Leonard after her guest appearance doesn't turn out well. Sheldon works on his sense of humour, and Raj practices talking to girls.

Penny makes a big step toward pursuing a full-time acting career, and Sheldon is forced to take a vacation.

Unable to score tickets for Comic-Con, Sheldon decides to stage his own comic-book convention, while the ladies attempt to act like grown-ups.

Amy talks Sheldon into a romantic Valentine's Day getaway to Napa Valley. Leonard and Penny make an emergency visit to the vet with Raj's dog.

Leonard's purchase of a new dining room table doesn't sit well with Sheldon, and Bernadette isn't happy about Howard taking another trip to space.

Things turn rocky between Sheldon and Wolowitz, and Bernadette steps in to mediate. Penny is offered a movie role that may prove embarrassing.

Frankie's parents, Pat and Tag, come to town to spend the holiday with the family much to Mike's dismay.

After years of never having time for themselves, Frankie and Mike decide to take charge of their lives and regain control over the Heck household.

Mike freezes Frankie out because he can't fathom how she inadvertently paid $200 for a small bottle of eye cream that she thought was priced at $20.

While Mary's away, George finds himself giving advice on Missy's love life. And Georgie has a solution for Meemaw's business woes.

While Missy asks some uncomfortable questions about sex in church, Meemaw and Georgie go into business together.

Sheldon takes his first engineering class with Professor Boucher. Meanwhile, Meemaw and Dale help take care of his ex-wife, June.

Sheldon's visit to see his mummy forces him to start addressing a new reality. The gang speculate about where they might be in 20 years.

Raj wrestles with dating two women at the same time, Penny is offered a part in a trashy movie, and Sheldon can't decide between two gaming systems.

Raj and Howard double-date, and the latter is flushed with embarrassment after Raj's girlfriend reveals a secret she knows about Howard.

Leonard reinstates Anything Can Happen Thursday, and Sheldon attempts something spontaneous. Raj requests help from Howard in prepping for a date.

Sheldon receives counselling from his childhood TV idol, while Penny and Leonard reach a relationship milestone and turn it into a competition.

A trying day at the movie shoot makes Penny question her life choices. Caring for a bedridden Mrs. Wolowitz is a challenge for Howard and Bernadette.

Sheldon gets caught up in all the life-altering changes going on around him and considers a monumental move. Raj and Emily take it to the next level.

Amy and Leonard take a road trip, Penny has an interview at Bernadette's company, and Howard has issues with Stuart's relationship with his mum.

Emma can help their lives move on by treating their skin. There's no quick fix for Roger's gout, and Amanda's lipoma is tricky.

I Know Exactly What This Is. Dr. Emma examines the mystery growths on Chris's scalp. Plus, she treats Cianca's debilitating hands and the after-effects of Dave's sunburn.

Don has a case of crippling psoriasis that has completely taken over his body. Jeff has a huge growth over his spine that looks like a hunchback.

Frankie's parents, Pat and Tag, come to town to spend the holiday with the family much to Mike's dismay.

After years of never having time for themselves, Frankie and Mike decide to take charge of their lives and regain control over the Heck household.

Mike freezes Frankie out because he can't fathom how she inadvertently paid $200 for a small bottle of eye cream that she thought was priced at $20.

Christmas is in full swing at HQ! Dr. Lee and her staff re-create classic Christmas movies with a pimple-y twist for holiday cards for their patients.

At over 600-lbs, Angie is trying to get to Houston to see Dr. Now and get life-saving weight-loss surgery. But a family conflict proves to be an obstacle.

Laura wants a frock to rock with her favourite leather jacket, and steam punk bride Julia needs a dress she can wear to the ceremony on a motorbike.

Randy's niece Danielle looks for a gown, and he surprises her with an amazing gift! Plus, bride Tracy is determined to find a black dress, but her mum disagrees.

Frankie's parents, Pat and Tag, come to town to spend the holiday with the family much to Mike's dismay.

After years of never having time for themselves, Frankie and Mike decide to take charge of their lives and regain control over the Heck household.

Mike freezes Frankie out because he can't fathom how she inadvertently paid $200 for a small bottle of eye cream that she thought was priced at $20.

While Mary's away, George finds himself giving advice on Missy's love life. And Georgie has a solution for Meemaw's business woes.

While Missy asks some uncomfortable questions about sex in church, Meemaw and Georgie go into business together.

Sheldon takes his first engineering class with Professor Boucher. Meanwhile, Meemaw and Dale help take care of his ex-wife, June.

Sheldon's visit to see his mummy forces him to start addressing a new reality. The gang speculate about where they might be in 20 years.

Raj wrestles with dating two women at the same time, Penny is offered a part in a trashy movie, and Sheldon can't decide between two gaming systems.

Raj and Howard double-date, and the latter is flushed with embarrassment after Raj's girlfriend reveals a secret she knows about Howard.

Leonard reinstates Anything Can Happen Thursday, and Sheldon attempts something spontaneous. Raj requests help from Howard in prepping for a date.

Sheldon receives counselling from his childhood TV idol, while Penny and Leonard reach a relationship milestone and turn it into a competition.

A trying day at the movie shoot makes Penny question her life choices. Caring for a bedridden Mrs. Wolowitz is a challenge for Howard and Bernadette.

Sheldon gets caught up in all the life-altering changes going on around him and considers a monumental move. Raj and Emily take it to the next level.

Amy and Leonard take a road trip, Penny has an interview at Bernadette's company, and Howard has issues with Stuart's relationship with his mum.

As the Super Bowl approaches, Mike is thrilled when Brick takes his advice and studies up on football - leading Axl to get jealous of his brother.

Frankie is elated when Axl asks her to accompany him to help pick out a present and choose a restaurant to impress his new girlfriend.

Fearing that a friendless Brick could be missing out on his childhood, Frankie makes it her mission to find a suitable friend for him.

While Sheldon battles the mysterious Grand Chancellor of the university over science requirements, Mary makes a shocking discovery about Georgie.

While George Sr. plays handyman at Brenda Sparks' house, Sheldon gets the science yips and has to learn how not to think.

Sheldon gets a dorm room all to himself, which soon becomes the campus hotspot. Meanwhile, Meemaw gets an unwanted business partner.

Howard signs up to take Sheldon's class, and tensions between Penny and Bernadette give Amy an opportunity to play one against the other.

NASA asks Wolowitz to throw the first pitch at an Angels baseball game. And Sheldon says that he and Amy are a better couple than Leonard and Penny.

Raj's girlfriend gives Penny the cold shoulder after he tells her about their history, and the guys consider buying into Stuart's comic-book emporium.

Amy and Bernadette accuse Penny of becoming a party pooper. And the guys brainstorm about inventing something cool.

Sheldon and Raj go on an expedition that turns into a test of how long before they get under each other's skin. Leonard and Penny argue about money.

Penny's sales pitch leaves a doctor-client smitten and the guys help her deal with it, and Bernadette and Amy debate female scientists and sexuality.

Amy and Bernadette organise a prom to be held atop the guys' apartment complex, but Sheldon is leery of all the prom pomp, circumstance and romancing.

Leonard needs surgery for a deviated septum, and Sheldon feels an operation is too dangerous and that his roommate may not make it out alive.

Mark's hands are 20 times bigger than normal. After learning that his condition may require amputation, Mark stopped seeing doctors.

Destinee & Dynastiee - Part 1. Identical twins Destinee and Dynastiee weigh over 1200 pounds combined. They determine to get healthy and lose weight together with Dr. Now's help.

Dr. Lee meets Dot, who has a large lump growing on her inner thigh. Plus, a new doctor helps 68-year-old Tim with his severe rhinophyma.

As the Super Bowl approaches, Mike is thrilled when Brick takes his advice and studies up on football - leading Axl to get jealous of his brother.

Frankie is elated when Axl asks her to accompany him to help pick out a present and choose a restaurant to impress his new girlfriend.

Fearing that a friendless Brick could be missing out on his childhood, Frankie makes it her mission to find a suitable friend for him.

Katrina suffers from oozing, smelly boils that have appeared all over her body. Plus, a patient with Neurofibromatosis seeks help from Dr. Lee.

At over 600-lbs each, Vianey and Allen are in a co-dependent relationship based on a shared love of food. Can they conquer their food addiction together.

Bride Lara beat a brain illness but the weight she gained makes dress shopping a trial - can David rebuild her confidence? Plus, tomboy Katie wants a young, fun frock.

Bride Samantha wants a dress with bling, but the one she wants is double her budget at $12,000. Krystina and her opinionated mum can't agree on style.

As the Super Bowl approaches, Mike is thrilled when Brick takes his advice and studies up on football - leading Axl to get jealous of his brother.

Frankie is elated when Axl asks her to accompany him to help pick out a present and choose a restaurant to impress his new girlfriend.

Fearing that a friendless Brick could be missing out on his childhood, Frankie makes it her mission to find a suitable friend for him.

While Sheldon battles the mysterious Grand Chancellor of the university over science requirements, Mary makes a shocking discovery about Georgie.

While George Sr. plays handyman at Brenda Sparks' house, Sheldon gets the science yips and has to learn how not to think.

Sheldon gets a dorm room all to himself, which soon becomes the campus hotspot. Meanwhile, Meemaw gets an unwanted business partner.

Howard signs up to take Sheldon's class, and tensions between Penny and Bernadette give Amy an opportunity to play one against the other.

NASA asks Wolowitz to throw the first pitch at an Angels baseball game. And Sheldon says that he and Amy are a better couple than Leonard and Penny.

Raj's girlfriend gives Penny the cold shoulder after he tells her about their history, and the guys consider buying into Stuart's comic-book emporium.

Amy and Bernadette accuse Penny of becoming a party pooper. And the guys brainstorm about inventing something cool.

Sheldon and Raj go on an expedition that turns into a test of how long before they get under each other's skin. Leonard and Penny argue about money.

Penny's sales pitch leaves a doctor-client smitten and the guys help her deal with it, and Bernadette and Amy debate female scientists and sexuality.

Amy and Bernadette organise a prom to be held atop the guys' apartment complex, but Sheldon is leery of all the prom pomp, circumstance and romancing.

Leonard needs surgery for a deviated septum, and Sheldon feels an operation is too dangerous and that his roommate may not make it out alive.

After Sue wins a family trip to New York, Murphy's Law goes into full effect and it's anything but a smooth flight when the family boards the plane.

Frankie quarrels with Brick's teacher, Ms. Rinsky, when Brick gets a 'D' on his math test and Frankie thinks bad teaching skills are to blame.

Spring Break turns out to be anything but peaceful when the family attempts to clean up 20 years of junk accumulated throughout the house.

Sheldon acts as Mary's spy when he's forced to spend the night at church for a youth lock-in. Meanwhile, Georgie gets attracted to an older woman.

Sheldon attends his first comic book convention, and Mary tries selling makeup.

Sheldon makes friends with his dorm neighbours. Meanwhile, George Sr. learns his job is in jeopardy.

Sheldon bids farewell to his Fun With Flags podcast. Leonard, Howard and Raj probe a late professor's research in search of some hidden significance.

Amy plans a Victorian dinner for Christmas Eve, while Raj, Leonard and Howard try to remove a pigeon that flew into the clean room at the university.

Raj awaits data from a space probe in which he was involved. Later, Leonard and Sheldon go dress shopping with Penny and Amy.

Sheldon becomes concerned that his cushy lifestyle is impacting his professional progress, so he asks the gang to make life more difficult for him.

An online troll rips Leonard and Sheldon's physics paper, and a girls' night out leads to Penny, Amy and Bernadette dishing about embarrassing events.

Howard gets unsettling news amidst the excitement of the comic book store reopening, and Penny doesn't practice what she preaches.

An experiment designed to make people fall in love piques Penny and Leonard's interest. Meanwhile, Leonard, Amy, Raj and Emily encounter a 'zombie.

There's trouble in paradise when Amy learns Sheldon signed up for a one-way mission to colonise Mars. Leonard makes an 'adult' purchase for Penny.

Ed Gamble, Richard Ayoade and Joanne McNally welcome some brilliant guest comedians to share their wild, unwise or downright unacceptable opinions.

A moronic mob bagman, his noisy girlfriend, and a closeted gay hit man all collide on a trip to Mexico to recover a supposedly cursed gun.