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Sheldon gets into trouble with fellow child genius Paige at the Science Museum, while George Sr. is forced to play therapist to Paige's parents.

When Meemaw gives Sheldon his first video game, it takes over their lives. Meanwhile, George Sr. gets jealous when Georgie bonds with Herschel.

Pemberton and Campbell charm America, so Sheldon and Amy bring Nobel laureates Kip Thorne, George Smoot and Frances Arnold to their side.

Amy has a meltdown due to the pressure associated with winning a Nobel Prize. Raj and Howard try to relive the good old days.

Raj is worried people won't take him seriously in his own field after publishing a paper that suggests he may have discovered alien life.

Kripke has proof that Dr. Pemberton plagiarized his thesis, and Sheldon and Amy aren't sure whether they should turn him in or not.

Leonard is surprised when Beverly is kind to him on a visit, until he finds out the real reason she's there. Denise and Stuart overstay their welcome.

Everything changes as Amy and Sheldon await big news. Howard and Bernadette leave their kids, while Leonard and Penny keep a secret.

Bernadette and Howard leave their kids, Penny and Leonard try to keep a secret, Sheldon and Amy stick together, and Raj makes a new friend.

Brilliant physicists Leonard and Sheldon meet new neighbour Penny, who shows them that although they're smart, they know very little about real life.

Part 2. As Amy plans a haunted Halloween wedding, old wounds with Tammy erupt into bitter fights, shocking accusations, and painful confrontations.

Emma treats patient Lorraine, whose dark patches of skin have shattered her confidence. And, Jonathan's eczema is so bad, he can't pick his kids up.

Rhonda has bumps all over her head, including a worrying horned growth. And, Dr. Lee treats Kevin, who has a huge lump protruding from his hip.

Frankie is made an example of in front of the entire class when she doesn't make a good impression on her first day of dental assisting school.

Frankie attempts to do a good deed for Thanksgiving by inviting a couple of Marines to celebrate the holiday with her family.

Mike is unhappy when he helps brother Rusty move some furniture into the Heck house garage and discovers that Rusty doesn't actually own the items.

Jen has growths on her ears that cause her depression, pain and vertigo. Plus, Juliet is in distress because of the bumps all over her neck and chest.

Melissa has isolated herself at home to avoid feeling the shame of her food addiction. She must seek help to rediscover her vibrant personality.

Bride Kayleigh wants a light, flowing dress with sparkle for her wedding in Mexico, and Karen seeks a baby pink frock for her pink-themed wedding in Cyprus.

Women in a throuple need dresses for their wedding. Plus, Ronnie has one more surprise for a COVID-19 frontline doctor who's getting married.

Frankie is made an example of in front of the entire class when she doesn't make a good impression on her first day of dental assisting school.

Frankie attempts to do a good deed for Thanksgiving by inviting a couple of Marines to celebrate the holiday with her family.

Mike is unhappy when he helps brother Rusty move some furniture into the Heck house garage and discovers that Rusty doesn't actually own the items.

Mary clashes with Sheldon's drama teacher Mr. Lundy over plans for a Halloween haunted house fundraiser for the church.

Sheldon gets into trouble with fellow child genius Paige at the Science Museum, while George Sr. is forced to play therapist to Paige's parents.

When Meemaw gives Sheldon his first video game, it takes over their lives. Meanwhile, George Sr. gets jealous when Georgie bonds with Herschel.

Pemberton and Campbell charm America, so Sheldon and Amy bring Nobel laureates Kip Thorne, George Smoot and Frances Arnold to their side.

Amy has a meltdown due to the pressure associated with winning a Nobel Prize. Raj and Howard try to relive the good old days.

Raj is worried people won't take him seriously in his own field after publishing a paper that suggests he may have discovered alien life.

Kripke has proof that Dr. Pemberton plagiarized his thesis, and Sheldon and Amy aren't sure whether they should turn him in or not.

Leonard is surprised when Beverly is kind to him on a visit, until he finds out the real reason she's there. Denise and Stuart overstay their welcome.

Everything changes as Amy and Sheldon await big news. Howard and Bernadette leave their kids, while Leonard and Penny keep a secret.

Bernadette and Howard leave their kids, Penny and Leonard try to keep a secret, Sheldon and Amy stick together, and Raj makes a new friend.

Brilliant physicists Leonard and Sheldon meet new neighbour Penny, who shows them that although they're smart, they know very little about real life.

As their 20th anniversary approaches, Frankie begins to think that Mike may be tiring of her company and is purposely trying to avoid her.

Axl is shocked to discover that he and Sue are enrolled in the same class. Brick's therapist attempts to teach him how to reach out to other students.

Feeling guilty over not spending enough time with the kids, Frankie and Mike dedicate each day of a three-day weekend to one of their offspring.

Sheldon studies his family for a psychology project when their Thanksgiving dinner turns into a fight after George Sr. is offered a job in Oklahoma.

When Sheldon learns that stunted childhoods can turn people into outcasts, he tries to act his age. Meemaw and Dr. Sturgis's relationship is tested.

While Missy unknowingly becomes Sheldon's test subject, Georgie joins Mary's Bible study to spend more time with his crush, Veronica.

Leonard volunteers to sign for a package to make a good impression on Penny, but things go terribly awry when he enlists Sheldon for help.

Leonard is depressed to learn that Penny is dating someone. Encouraged by his friends and fellow scientists, he asks a colleague out on a date.

Sheldon gets fired and explores what life has to offer outside physics, leaving Leonard to take drastic action to snap his friend out of his funk.

Fearing he's wasting his time on Penny, Leonard makes a connection with Leslie. Meanwhile, Sheldon frets over a change to his hamburger routine.

Penny hosts a Halloween party, putting Leonard, Sheldon, Wolowitz and Koothrappali through a new test of their social skills.

When Wolowitz goes AWOL with one of her friends, Penny's recruited to fill in for him on the guys' Halo team.

Raj's parents set him up on a blind date, and when he discovers he can talk to her, she shows interest in Sheldon.

When they're invited to present at a physics conference, Sheldon's reluctance to share the credit leads to a tiff between him and Leonard.

In Turkey, the world's tallest woman lives with an unknown genetic condition, while in Brazil, the world's shortest couple navigate dwarfism.

A woman goes into labour but flatlines on the delivery table. Raccoons invade a house, and an extreme workout leads to calling 911.

Gerald returns to see Dr. Lee and a hand specialist about a huge, intrusive bump on his finger. Vinnie has an embarrassing birthmark on his neck.

As their 20th anniversary approaches, Frankie begins to think that Mike may be tiring of her company and is purposely trying to avoid her.

Axl is shocked to discover that he and Sue are enrolled in the same class. Brick's therapist attempts to teach him how to reach out to other students.

Feeling guilty over not spending enough time with the kids, Frankie and Mike dedicate each day of a three-day weekend to one of their offspring.

Lee Nose Best! Tony has large growths on his nose that impair his breathing. Can Dr. Lee help? And, Marie has an unsightly lump on her forehead that makes her a hermit.

Kenae' was already big before her beloved mother died. Refusing to deal with the pain, she turned to food to fill the void, eating herself to over 600 pounds.

West End star Michelle wants a timeless dress for her wedding at St Paul's Cathedral. Drama queen Lois seeks a theatrical style - can the team find a frock.

If Chef Huda can't get her entourage to agree, this contest between ball gown and mermaid will have no winners, just losers! Plus, Valerie seeks a black dress.

As their 20th anniversary approaches, Frankie begins to think that Mike may be tiring of her company and is purposely trying to avoid her.

Axl is shocked to discover that he and Sue are enrolled in the same class. Brick's therapist attempts to teach him how to reach out to other students.

Feeling guilty over not spending enough time with the kids, Frankie and Mike dedicate each day of a three-day weekend to one of their offspring.

Sheldon studies his family for a psychology project when their Thanksgiving dinner turns into a fight after George Sr. is offered a job in Oklahoma.

When Sheldon learns that stunted childhoods can turn people into outcasts, he tries to act his age. Meemaw and Dr. Sturgis's relationship is tested.

While Missy unknowingly becomes Sheldon's test subject, Georgie joins Mary's Bible study to spend more time with his crush, Veronica.

Leonard volunteers to sign for a package to make a good impression on Penny, but things go terribly awry when he enlists Sheldon for help.

Leonard is depressed to learn that Penny is dating someone. Encouraged by his friends and fellow scientists, he asks a colleague out on a date.

Sheldon gets fired and explores what life has to offer outside physics, leaving Leonard to take drastic action to snap his friend out of his funk.

Fearing he's wasting his time on Penny, Leonard makes a connection with Leslie. Meanwhile, Sheldon frets over a change to his hamburger routine.

Penny hosts a Halloween party, putting Leonard, Sheldon, Wolowitz and Koothrappali through a new test of their social skills.

When Wolowitz goes AWOL with one of her friends, Penny's recruited to fill in for him on the guys' Halo team.

Raj's parents set him up on a blind date, and when he discovers he can talk to her, she shows interest in Sheldon.

When they're invited to present at a physics conference, Sheldon's reluctance to share the credit leads to a tiff between him and Leonard.

Mike is upset with Frankie when he discovers that she set him up on an adult playdate with a new neighbour who shares the same interests.

Frankie and Mike worry that Axl isn't receiving any college acceptance letters. Meanwhile, Sue is determined to prove that smiling is contagious.

Axl and his friends make a profit on broken hearts. And, Mike accidentally sends a romantic text meant for Frankie to a co-worker at the quarry.

When Sheldon has to spend a few days in the hospital, he turns into the world's worst patient, and his behaviour takes a toll on everyone.

While Sheldon attempts to build a nuclear reactor to power the neighbourhood, Georgie is heartbroken when he learns that Veronica has a boyfriend.

Sheldon uses his new friendship with the school bully to boss Georgie around. Also, Missy steals Meemaw's makeup for Picture Day.

Leonard and Sheldon each lie to avoid hearing Penny sing in a production of Rent. However, Sheldon's lie becomes a bit too complicated.

With his friends knowing how sour he acts when sick and avoiding him as a result, Sheldon is nursed by Penny, who hasn't a clue what she's in for.

With Sheldon rattled after meeting Dennis, a teen physicist who's smarter than he is, the rest of the guys search for a way to eliminate the threat.

Sheldon finds himself booted from the gang's Physics Bowl team and replaced with Leslie, so he forms his own team hoping to prove he's superior.

When the delivery of a full-size prop of 1960's 'The Time Machine' causes Penny to miss work, she scolds Leonard about his sci-fi collectibles.

The gang fall for Sheldon's twin sister, and Leonard's plan to win her heart is derailed when Sheldon declares he'll decide who can date her.

Penny wants to throw a surprise party for Leonard, but Sheldon's indulgence at an electronics store throws her off-track.

Penny's breakup spurs Leonard to summon the courage to ask her out, and they both go to Sheldon for advice on their upcoming date.

Tightly wound Detective David Starsky is forced to partner with easy-going Detective Ken Hutchinson to solve a high-stakes narcotics case.

Cystem Shutdown! Gerard has nearly a hundred lumps varying in size all over his body. Eric has a large bump on his head that he calls his 'on/off button.