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Eric hopes Dr. Lee can remove the giant growth from his backside. Plus, Michael makes jokes, but he knows the bump on his head is anything but funny.

Dr. Lee meets Jon, who suffers from a huge bump on his shoulder blade. Plus, April wants to get married but feels hideous due to her bumpy underarm.

Dr. Lee meets with Tobi, who has symmetrical bumps around her spine. Later, Dr. Tomassian learns how to remove a huge, floppy arm bump.

Lifelong secret eater Nikki is threatened by immobility as her weight climbs to 650-lbs. She has a gastric bypass and confronts the emotional causes for her eating.

Weighing over 700 pounds at 26-years-old, the clock is ticking on Ashley's life. Ashamed of her body, surgery offers hope, but not without setbacks.

At 700 pounds, Chad undergoes gastric bypass surgery. He quickly sheds pounds, but faces a medical crisis when he does not follow the doctor's orders.

Lauren wants to look like a 'classy porn star' at her wedding, but she is in for a surprise. Bride Cheryl is racked with indecision over her gown.

Keturah has her heart set on a fishtail gown, but her brother suggests a princess look. And, Karen's dreams for a ball gown may not come true.

Nichale always dreamed of a fishtail style, but mum is paying, and she wants a princess dress! Kayleigh returns after a massive meltdown, will she be happy with her gown.

Ayesha falls in love with the first dress she tries on, but also loves the second dress as well! Plus, Nichale has another fitting and finds her dress is too small.

When Mary bans Sheldon from reading a mature comic book, Sheldon decides it's time to assert his independence from his mother.

When Sheldon is no longer academically challenged at Medford High, he audits a college class taught by a professor.

A heated argument erupts between the Coopers and their neighbours when a new dog terrorises Sheldon.

While Sheldon is obsesses over Meemaw's budding relationship with his mentor, Dr. Sturgis, George and Mary attempt to bond with their other kids.

When Meemaw is pursued by two gentlemen callers, Sheldon interferes, forcing her to set some ground rules.

Sheldon dismantles the refrigerator to stop an annoying hum and then must get a paper route to pay for the repairs.

Mandy's attempt to help Missy with boys backfires when Mary finds out and Georgie is caught in the crossfire.

When CeeCee loses her favourite toy, Mandy and Meemaw take it as an opportunity to make some money.

Leonard tries to secure the perfect wedding venue for Sheldon and Amy. Bernadette and Howard have a hard time deciding who should go back to work.

Bill Gates' company wants to partner with Penny's pharmaceutical company. Leonard, Raj and Howard do everything in their power to meet him.

Leonard decides to run against Sheldon for president of the tenants' association. Bernadette encourages Howard and Raj to find the owner of a drone.

A reclusive scientist invites Sheldon to his remote cabin. Penny and Bernadette improvise after Amy doesn't like the bachelorette they planned.

Sheldon's comic book store experience changes when Neil Gaiman puts Stuart's store on the map. And Raj takes credit for Penny's astronomical discovery.

Sheldon goes to Vegas to win money for science. Penny and Bernadette take Amy wedding dress shopping, but her choice entangles them in a web of lies.

Sheldon and Leonard travel to Texas to end a family feud. The Wolowitz kids inadvertently infest Amy, Bernadette, Howard and Raj with pinkeye.

When Amy's parents and Sheldon's family arrive, everybody is focused on making sure all goes according to plan - everyone except the bride and groom.

Sheldon and Amy's honeymoon runs aground, while Penny and Leonard discover similarities with Amy's parents. Raj insults physicist Neil deGrasse Tyson.

Sheldon and Amy try to figure out what 'perfect gift' Leonard and Penny gave them. Raj asks his father to arrange a marriage for him.

Stuart starts bringing his new girlfriend home, Penny and Leonard talk about starting a family, and Raj explores an arranged marriage.

Sheldon won't tell anyone why he's never mentioned his childhood friend Tam. Bernadette and Penny take out Raj's fiancée to get the skinny on her.

Amy doesn't have time to work on a project, so Sheldon goes to great lengths to ensure she can work with him, even if it means sabotaging her career.

When Howard dresses up as Sheldon for Halloween, Sheldon seeks retaliation. Leonard is shocked that Penny doesn't remember their first kiss.

Leonard is caught in a tough spot when he's responsible for distributing extra grant money. Bernadette turns the backyard playhouse into a hideaway.

Sheldon tries to bond with Amy's father, but Howard lures Mr. Fowler away with magic tricks. Raj and Anu try to get physical for the first time.

Sheldon and Amy are devastated learning that Super Asymmetry has been discovered and disproven. Bernadette asks Denise to help her win a videogame.

A VHS tape inspires Sheldon to not give up on his and Amy's theory. Bernadette turns into a pageant mom over Howard's Magic Castle audition.

Penny and Leonard organise a paintball game that results in mayhem. Raj catches Anu with her ex, and Stuart doesn't want to move in with Denise.

Penny's ex, Zack, and his wife want a baby, but when Zack is infertile, they ask Leonard to help. Raj attempts to mend things with his ex-fiancée.

Dara Ó Briain extracts humour from current events with guests Rhys James, Neil Delamere, Milton Jones, Zoe Lyons, Sara Pascoe and Ahir Shah.

Dara Ó Briain introduces topical chat and hilarious games with guests Rhys James, Ahir Shah, Angela Barnes, Lou Sanders, Ed Byrne and Milton Jones.

Dara Ó Briain extracts humour from current events with guests Rhys James, Neil Delamere, Milton Jones, Zoe Lyons, Sara Pascoe and Ahir Shah.

When Dr. Sturgis bonds with Paige, another 10-year-old genius, Sheldon gets jealous. Meanwhile, Mary invites Paige's family over for a play date.

Jack fainted during a previous attempt to remove his throat bump. Can Dr. Lee help this time? Plus, Dr. Tomassian reconstructs Victoria's earlobes.

Pimple Popper. Angelina's huge chest lump affects her love life and Delano has a football-sized mass on his back. Plus, Carla hopes to get painful cysts removed from her scalp.

At 670 pounds, Ashley is desperate to save her life and her marriage to husband David. Can weight-loss surgery give her the chance for a family of her own.

New mum Laura has seen her dream dress online, but will she love its lacey A-line style in real life? Lutifah has two wedding gowns, but fears they won't fit.

Kristin wants the advice of her friends to help her find the perfect gown. Problems arise when she thinks she's found the one, but her friends don't agree.

Nikki looks for a dress that will wow at her big fat Greek wedding. Stephanie is keen to show off her newly slender figure and hopes to find a fitted frock.

The Hecks spend New Year's Day at the Orson Escape Room. Mike is stunned when Frankie reveals that she had a romantic dream involving Frank Sinatra.

Frankie is elated when she wins a month of free maid service. Axl, Hutch and Kenny attempt to move in with Sue and Lexie in their college housing.

Brad agrees to coach Sue's no-cut acapella group. Brick asks for Frankie and Mike's advice when girlfriend Cindy tells him that he reads too much.

When Meemaw is pursued by two gentlemen callers, Sheldon interferes, forcing her to set some ground rules.

Sheldon dismantles the refrigerator to stop an annoying hum and then must get a paper route to pay for the repairs.

When Dr. Sturgis bonds with Paige, another 10-year-old genius, Sheldon gets jealous. Meanwhile, Mary invites Paige's family over for a play date.

Amy doesn't have time to work on a project, so Sheldon goes to great lengths to ensure she can work with him, even if it means sabotaging her career.

When Howard dresses up as Sheldon for Halloween, Sheldon seeks retaliation. Leonard is shocked that Penny doesn't remember their first kiss.

Leonard is caught in a tough spot when he's responsible for distributing extra grant money. Bernadette turns the backyard playhouse into a hideaway.

Sheldon tries to bond with Amy's father, but Howard lures Mr. Fowler away with magic tricks. Raj and Anu try to get physical for the first time.

Sheldon and Amy are devastated learning that Super Asymmetry has been discovered and disproven. Bernadette asks Denise to help her win a videogame.

A VHS tape inspires Sheldon to not give up on his and Amy's theory. Bernadette turns into a pageant mom over Howard's Magic Castle audition.

Penny and Leonard organise a paintball game that results in mayhem. Raj catches Anu with her ex, and Stuart doesn't want to move in with Denise.

Penny's ex, Zack, and his wife want a baby, but when Zack is infertile, they ask Leonard to help. Raj attempts to mend things with his ex-fiancée.

Frankie is sad when informed that her days of having kids are over. Sue and Axl are shocked when her roommate and Sean Donahue start flirting.

Frankie and Mike frantically attempt to shut off the water when the pipes burst. The Hecks call a meeting to deal with their bickering.

Mike's dislike of dentistry leads to escalating falsehoods to avoid having his toothache fixed. Brick attempts to write a Scottish-themed rap musical.

When Mary's faith is shaken by a tragedy in the community, Sheldon becomes an unlikely ally.

When George Sr. asks Sheldon to keep a secret from Mary, the stress of not being honest drives Sheldon to hide out at Tam's for his first sleepover.

Dr. Sturgis recommends Sheldon and Missy for a university research study on twins, and Mary is unhappy when the test results go to Sheldon's head.

Sheldon and Amy's theory is proven by two physicists, who then try to kick Amy off the Nobel nomination. Bernadette has a big success at work.

Sheldon helps Bernadette and Howard navigate bureaucratic paperwork. Leonard is disappointed when his friends exclude him from a scientific project.

Penny tries to seduce an abstaining Leonard to ruin his 'donation' for her ex-boyfriend and his wife. Raj's cancelled bachelor party takes a turn.

The gang finds out Wil Wheaton hosts a celebrity Dungeons and Dragons game. Deception and betrayal are the path to make it to the one open seat.

While Bernadette is away and Howard is in charge of the kids, Sheldon finds a book on experimenting on kids. The guys plus Amy make a day of it.

Pemberton and Campbell charm America, so Sheldon and Amy bring Nobel laureates Kip Thorne, George Smoot and Frances Arnold to their side.

Amy has a meltdown due to the pressure associated with winning a Nobel Prize. Raj and Howard try to relive the good old days.

Raj is worried people won't take him seriously in his own field after publishing a paper that suggests he may have discovered alien life.

Dara Ó Briain extracts humour from current events with guests Rhys James, Neil Delamere, Milton Jones, Zoe Lyons, Sara Pascoe and Ahir Shah.

After their house is trashed without an obvious cause, a couple install video surveillance to record the chilling supernatural events in their house.

Frankie is sad when informed that her days of having kids are over. Sue and Axl are shocked when her roommate and Sean Donahue start flirting.

Frankie and Mike frantically attempt to shut off the water when the pipes burst. The Hecks call a meeting to deal with their bickering.

Mike's dislike of dentistry leads to escalating falsehoods to avoid having his toothache fixed. Brick attempts to write a Scottish-themed rap musical.

Melissa covered her huge lipoma with a sweatshirt for years. Tyler's fear of cancer stopped his head lumps being diagnosed and Tahj is covered in painful boils.

44-year old Erica binges on food when faced with adversity, and previous weight-loss surgery was unsuccessful. Can she get the support she needs to change her habits.

To Show Or Not To Show. Sacha wants a dress that pushes the envelope and helps her shine. And, new mum Amy wants a gown that will really wow her fiancé.

Sophie wants to show it all off for her wedding day but finding the line between sexy and trashy is proving tricky. Plus, Sasha is back for her first fitting.

Rochelle and her mother can only agree on one thing - a dress with a mermaid style silhouette. Bride Nicole is struggling with the idea of glitz on her frock.

Frankie is sad when informed that her days of having kids are over. Sue and Axl are shocked when her roommate and Sean Donahue start flirting.

Frankie and Mike frantically attempt to shut off the water when the pipes burst. The Hecks call a meeting to deal with their bickering.

Mike's dislike of dentistry leads to escalating falsehoods to avoid having his toothache fixed. Brick attempts to write a Scottish-themed rap musical.

When Mary's faith is shaken by a tragedy in the community, Sheldon becomes an unlikely ally.

When George Sr. asks Sheldon to keep a secret from Mary, the stress of not being honest drives Sheldon to hide out at Tam's for his first sleepover.

Dr. Sturgis recommends Sheldon and Missy for a university research study on twins, and Mary is unhappy when the test results go to Sheldon's head.

Sheldon and Amy's theory is proven by two physicists, who then try to kick Amy off the Nobel nomination. Bernadette has a big success at work.

Sheldon helps Bernadette and Howard navigate bureaucratic paperwork. Leonard is disappointed when his friends exclude him from a scientific project.

Penny tries to seduce an abstaining Leonard to ruin his 'donation' for her ex-boyfriend and his wife. Raj's cancelled bachelor party takes a turn.

The gang finds out Wil Wheaton hosts a celebrity Dungeons and Dragons game. Deception and betrayal are the path to make it to the one open seat.

While Bernadette is away and Howard is in charge of the kids, Sheldon finds a book on experimenting on kids. The guys plus Amy make a day of it.

Pemberton and Campbell charm America, so Sheldon and Amy bring Nobel laureates Kip Thorne, George Smoot and Frances Arnold to their side.

Amy has a meltdown due to the pressure associated with winning a Nobel Prize. Raj and Howard try to relive the good old days.

Raj is worried people won't take him seriously in his own field after publishing a paper that suggests he may have discovered alien life.

Lexie confesses to Sue that she has a crush on Axl. Mike hires high school coach Babbitt to pull the quarry softball team out of their slump.

Axl thinks the universe is trying to tell him something when he runs into just about all of his ex-girlfriends at a St. Patrick's Day party.

Bill Norwood is so upset with Mike for poaching his plumber their friendship could be at risk. Brick spends a weekend with Axl at college to party.

Mary clashes with Sheldon's drama teacher Mr. Lundy over plans for a Halloween haunted house fundraiser for the church.

Sheldon gets into trouble with fellow child genius Paige at the Science Museum, while George Sr. is forced to play therapist to Paige's parents.

When Meemaw gives Sheldon his first video game, it takes over their lives. Meanwhile, George Sr. gets jealous when Georgie bonds with Herschel.

Kripke has proof that Dr. Pemberton plagiarized his thesis, and Sheldon and Amy aren't sure whether they should turn him in or not.

Leonard is surprised when Beverly is kind to him on a visit, until he finds out the real reason she's there. Denise and Stuart overstay their welcome.

Everything changes as Amy and Sheldon await big news. Howard and Bernadette leave their kids, while Leonard and Penny keep a secret.

Bernadette and Howard leave their kids, Penny and Leonard try to keep a secret, Sheldon and Amy stick together, and Raj makes a new friend.

Brilliant physicists Leonard and Sheldon meet new neighbour Penny, who shows them that although they're smart, they know very little about real life.

Leonard volunteers to sign for a package to make a good impression on Penny, but things go terribly awry when he enlists Sheldon for help.

Leonard is depressed to learn that Penny is dating someone. Encouraged by his friends and fellow scientists, he asks a colleague out on a date.

Sheldon gets fired and explores what life has to offer outside physics, leaving Leonard to take drastic action to snap his friend out of his funk.

Andrea and Tammy get bad news about their wedding, and Amy's opportunity-of-a-lifetime may tear the family apart as Tammy makes a surprise request.

Nesha's BBW speed dating event gets off to a rocky start. Jaz pushes for independence and attempts to train Nesha and Nana for their 5K.

Dara Ó Briain extracts humour from current events with guests Rhys James, Neil Delamere, Milton Jones, Zoe Lyons, Sara Pascoe and Ahir Shah.

Lexie confesses to Sue that she has a crush on Axl. Mike hires high school coach Babbitt to pull the quarry softball team out of their slump.

Axl thinks the universe is trying to tell him something when he runs into just about all of his ex-girlfriends at a St. Patrick's Day party.

Bill Norwood is so upset with Mike for poaching his plumber their friendship could be at risk. Brick spends a weekend with Axl at college to party.

Half of Mary's body is a size 18 while the other is an 8. Anthony's cyst is in the area called the Triangle of Death, and Shane wants to get a lump off his back.

Single mother-of five-Cynthia works as a special needs teacher, but that is becoming impossible at 610 pounds - now both her life and her family at risk.

The Feel Good, Look Good Show. Emily hates to shop, so she's relying on her BFFs - will they choose style or comfort? Hayley's pregnancy means a new gown to accommodate a baby bump.

Ellie has her heart set on a vintage lace fishtail dress, but her mum is angling for a ball gown. Plus, Laura finds the perfect gown with a sexy fit and flare.

Lauren wants two dresses, one for the ceremony and a slinky number for the reception. Can her pragmatic entourage convince her to stick to just one dress.

Lexie confesses to Sue that she has a crush on Axl. Mike hires high school coach Babbitt to pull the quarry softball team out of their slump.

Axl thinks the universe is trying to tell him something when he runs into just about all of his ex-girlfriends at a St. Patrick's Day party.

Bill Norwood is so upset with Mike for poaching his plumber their friendship could be at risk. Brick spends a weekend with Axl at college to party.

Mary clashes with Sheldon's drama teacher Mr. Lundy over plans for a Halloween haunted house fundraiser for the church.

Sheldon gets into trouble with fellow child genius Paige at the Science Museum, while George Sr. is forced to play therapist to Paige's parents.

When Meemaw gives Sheldon his first video game, it takes over their lives. Meanwhile, George Sr. gets jealous when Georgie bonds with Herschel.

Kripke has proof that Dr. Pemberton plagiarized his thesis, and Sheldon and Amy aren't sure whether they should turn him in or not.

Leonard is surprised when Beverly is kind to him on a visit, until he finds out the real reason she's there. Denise and Stuart overstay their welcome.

Everything changes as Amy and Sheldon await big news. Howard and Bernadette leave their kids, while Leonard and Penny keep a secret.

Bernadette and Howard leave their kids, Penny and Leonard try to keep a secret, Sheldon and Amy stick together, and Raj makes a new friend.

Brilliant physicists Leonard and Sheldon meet new neighbour Penny, who shows them that although they're smart, they know very little about real life.

Leonard volunteers to sign for a package to make a good impression on Penny, but things go terribly awry when he enlists Sheldon for help.

Leonard is depressed to learn that Penny is dating someone. Encouraged by his friends and fellow scientists, he asks a colleague out on a date.

Sheldon gets fired and explores what life has to offer outside physics, leaving Leonard to take drastic action to snap his friend out of his funk.

Frankie and Mike send Brick to a religious weekend camp. He is shocked to discover that his bunkmate is the boy he was switched at birth with.

Frankie is thrilled when Axl agrees to let her take him shopping to help him pick out a suit. Mike threatens to get rid of the pool if no one's using it.

Frankie frantically searches the house for Axl's missing graduation gift. Sue decides that she wants to make a sweet video for Mike's upcoming birthday.

Sheldon studies his family for a psychology project when their Thanksgiving dinner turns into a fight after George Sr. is offered a job in Oklahoma.

When Sheldon learns that stunted childhoods can turn people into outcasts, he tries to act his age. Meemaw and Dr. Sturgis's relationship is tested.

While Missy unknowingly becomes Sheldon's test subject, Georgie joins Mary's Bible study to spend more time with his crush, Veronica.

Fearing he's wasting his time on Penny, Leonard makes a connection with Leslie. Meanwhile, Sheldon frets over a change to his hamburger routine.

Penny hosts a Halloween party, putting Leonard, Sheldon, Wolowitz and Koothrappali through a new test of their social skills.

When Wolowitz goes AWOL with one of her friends, Penny's recruited to fill in for him on the guys' Halo team.

Raj's parents set him up on a blind date, and when he discovers he can talk to her, she shows interest in Sheldon.

When they're invited to present at a physics conference, Sheldon's reluctance to share the credit leads to a tiff between him and Leonard.

Leonard and Sheldon each lie to avoid hearing Penny sing in a production of Rent. However, Sheldon's lie becomes a bit too complicated.

With his friends knowing how sour he acts when sick and avoiding him as a result, Sheldon is nursed by Penny, who hasn't a clue what she's in for.

With Sheldon rattled after meeting Dennis, a teen physicist who's smarter than he is, the rest of the guys search for a way to eliminate the threat.

Ravi receives life-changing surgery to remove the huge tumours that cover his face. Lauren has 24-hour treatment to prolong her life.

Natalie suffered major, life-changing burns after a bonfire explosion. Now, aged 18, she's not letting her burns hold her back.

Belinda's lump on her neck causes her to be immobile. Nicole won't get married until she gets her arm pit lump removed. And, Nick unwisely removed a lipoma at home.