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Sheldon and Amy subject their friends to a series of experiments to choose the best man and maid of honour. And Penny reveals her true feelings.

Amy and Leonard bond during a series of experiments. Bert replaces Howard in Footprints on the Moon, and Sheldon finds Penny a source of inspiration.

Lisa makes an unexpected decision about Daniel's proposal. Jovon and Annalyn's honeymoon is off to a rocky start. Aviva grows suspicious of Stig.

Georgie discovers that Jim's annual tire convention trip isn't what he says it is. Meanwhile, Mandy has doubts about the strength of her marriage.

Audrey and Mary go to war over CeeCee and Georgie, and Mandy can't help but take sides.

Steven's bump is so large, his daughter thinks he is growing a monster on his back. Ethan suffers from an irritating rash in an awkward place on his body.

John lost his sight at a young age and soon after began growing lumps on his body. Lynette has hundreds of pebble-sized bumps on her arms, chest, and belly.

At age 58, Rose had almost given up and eaten herself to death. She has more than 400-lbs to lose if she wants to get healthy for her family.

Randy Will Show You The Door. Bridal model Jessica brings her outspoken clique with her to Kleinfeld's, but Randy threatens to kick them out. Plus, Marlo returns with her frank twin.

Randy's niece Danielle looks for a gown, and he surprises her with an amazing gift! Plus, bride Tracy is determined to find a black dress, but her mum disagrees.

Sheldon campaigns to become Dr. Linkletter's lab assistant. Georgie enlists the drama teacher, to help with a surprising business venture.

Dr. Linkletter pushes Sheldon to make friends with his fellow students, and Georgie gets a pager.

Sheldon, Dr. Linkletter and Meemaw team up on a science experiment. Mary is jealous that Pastor Jeff and Brenda are spending so much time together.

The Geezer Bus And A New Model. Sheldon refuses to ride in a car after getting into an accident with Meemaw. Meemaw is forced to take the church shuttle.

When the IRS accuses Sheldon of making a mistake, he stops at nothing to prove them wrong. Meanwhile, Dale is forced to get a colonoscopy.

Sheldon faces consequences after installing a pirated computer game. Mary and Meemaw take Brenda out for Girls Night, and George watches Billy.

Georgie discovers that Jim's annual tire convention trip isn't what he says it is. Meanwhile, Mandy has doubts about the strength of her marriage.

Audrey and Mary go to war over CeeCee and Georgie, and Mandy can't help but take sides.

Sheldon stays with Bernadette while the rest of the gang attends an event where they run into Penny's former boyfriend and meet Raj's girlfriend.

Sheldon hires Stuart to spend the day with Amy. Meanwhile Leonard's mother visits, and Penny just can't seem to connect with her.

Leonard's recently divorced parents roll into town, as does Sheldon's holy-roller mother, and all hell breaks loose.

The gang deals with the awkward aftermath of an overnight liaison between Sheldon's mum and Leonard's dad. Penny's dysfunctional family is in town.

An Air Force bigwig approaches the guys about their revolutionary invention, and Bernadette is upset with Penny after she accidentally leaks a secret.

Howard and Leonard are putting in late nights at work, Raj and a pregnant Bernadette spend a day together, and Penny and Amy take in a faculty party.

Sheldon and Amy decide to move in together. Meanwhile, Howard and Bernadette become upset when Raj learns the gender of their baby before they do.

Sheldon accuses Amy of not following the bathroom schedule. Meanwhile, Howard and Bernadette's staycation is interrupted by hot tub interlopers.

Feeling his baby kick sends Howard on a baby-items buying binge with Raj, Sheldon and Amy host a brunch, and Penny is invited to a sci-fi convention.

Amy fibs about repairs being made to her apartment. Later, they present a episode of 'Fun with Flags' in Penny's apartment.

A successful gene experiment leaves Sheldon excited to procreate with Amy. Raj is reluctant to reveal what his new woman does for a living.

A coworker's MacArthur Genius fellowship award leaves Sheldon stone cold jealous. Howard finds a remote-control Stephen Hawking action figure.

A divide develops between Sheldon and Leonard when divvying up their shared belongings. Raj and Stuart battle to provide Bernadette the most help.

While Sheldon and Amy celebrate Amy's birthday, Howard and Bernadette welcome their new Baby Wolowitz.

Sheldon and Amy visit Leonard and Penny for the first time since the holidays and share details about their terrible trip to Texas.

After a disagreement, Penny takes off for a spa weekend, and Sheldon plays peacemaker. Howard and Raj battle a noisy floor in the baby's room.

Sheldon tests an MIT invention, Leonard has trouble when Penny announces her brother's visit, and Raj seeks advice from old girlfriends.

Leonard and Howard engineer a distraction for Sheldon to keep him from hindering progress on the guidance-system project.

Amy is incensed when she learns Sheldon has shared intimate relationship information, and Raj's father stops sending financial support.

Raj finds himself in a cash crunch and turns to Sheldon to help him. Meanwhile, Penny considers crashing the guys' annual Comic-Con getaway.

Really ridiculously good-looking fashion model Derek Zoolander is hired to stop a secret cartel of political assassins posing as male models.