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Lively sisters Amy and Tammy Slaton are both morbidly obese. As they continue their weight-loss journey, there are more ups and downs than ever.

Amy and Tammy have drifted further than ever, but unbeknownst to them, are living parallel lives as their romantic partnerships both take big steps.

Firefighter Jimmy has numerous torso bumps that make it painful to play with his young son. Plus, Steven has a mystery bump on the back of his head.

John would love to date but is embarrassed about a huge bump on his cheek. Denise sees Dr. Lee about a growth on her booty.

Dr. Lee removes a painful bump from Christian's back, all while his stuffed animal companion watches. Plus, Soniya suffers from dark spots.

For Larry, a second weight loss surgery would mean another chance at a career as a gospel recording artist. He must change his eating addiction and take control.

Mum of 18, Michelle Duggar brings her family to help her find a dress for her vow renewal. Bride Beatrize has a list of 40 dresses she wants to look at.

Maria brings three generations of her family to her appointment. Meanwhile, Pamela is on the hunt for a grand ballroom style dress, but how will she get on.

Heather brings her 3 bridesmaids to the store. Meredith has no idea what style she is looking for. Isabel is accompanied by her fiance and style guru to the salon.

Magdalonie brings five outspoken bridesmaids to her appointment. Plus, rugby player Michele, who is battling Lymphoma, visits the salon with her fiance, mum and aunt.

Deciding to pursue new hobbies before becoming parents, Molly encourages Mike to take up roller-skating with her.

Mike goes on a junk food binge to cope with missing Molly, while she's away. Meanwhile, Carl contemplates leaving Chicago.

Molly is so focused on her job that she doesn't notice a fellow teacher hitting on her. Vince talks Mike into his latest money-making scheme.

Sheldon gets a dorm room all to himself, which soon becomes the campus hotspot. Meanwhile, Meemaw gets an unwanted business partner.

Sheldon acts as Mary's spy when he's forced to spend the night at church for a youth lock-in. Meanwhile, Georgie gets attracted to an older woman.

Sheldon attends his first comic book convention, and Mary tries selling makeup.

Penny and Leonard organise a paintball game that results in mayhem. Raj catches Anu with her ex, and Stuart doesn't want to move in with Denise.

Penny's ex, Zack, and his wife want a baby, but when Zack is infertile, they ask Leonard to help. Raj attempts to mend things with his ex-fiancée.

Sheldon and Amy's theory is proven by two physicists, who then try to kick Amy off the Nobel nomination. Bernadette has a big success at work.

Sheldon helps Bernadette and Howard navigate bureaucratic paperwork. Leonard is disappointed when his friends exclude him from a scientific project.

Penny tries to seduce an abstaining Leonard to ruin his 'donation' for her ex-boyfriend and his wife. Raj's cancelled bachelor party takes a turn.

The gang finds out Wil Wheaton hosts a celebrity Dungeons and Dragons game. Deception and betrayal are the path to make it to the one open seat.

While Bernadette is away and Howard is in charge of the kids, Sheldon finds a book on experimenting on kids. The guys plus Amy make a day of it.

Pemberton and Campbell charm America, so Sheldon and Amy bring Nobel laureates Kip Thorne, George Smoot and Frances Arnold to their side.

Mike and Carl get stuck working at the Renaissance Faire after their boss, Captain Murphy, gets dumped by Mike's mother.

Molly finds herself at a crossroads with her career and makes a huge decision to leave her teaching job to become a writer.

Poker In Front, Looker In Back. Molly recruits Joyce to spy on her next-door neighbour. Mike and the guys get together for a poker game and end up sharing their hopes and dreams.

Sheldon makes friends with his dorm neighbours. Meanwhile, George Sr. learns his job is in jeopardy.

When a new scientist, Dr. Lee, joins the lab, Sheldon is the odd man out. Meanwhile, Mary is given a lotto ticket.

Sheldon joins Dr. Linkletter and Dr. Sturgis on a science road trip, landing them in the middle of nowhere. Georgie continues to lie about his age.

Amy has a meltdown due to the pressure associated with winning a Nobel Prize. Raj and Howard try to relive the good old days.

Raj is worried people won't take him seriously in his own field after publishing a paper that suggests he may have discovered alien life.

Kripke has proof that Dr. Pemberton plagiarized his thesis, and Sheldon and Amy aren't sure whether they should turn him in or not.

Leonard is surprised when Beverly is kind to him on a visit, until he finds out the real reason she's there. Denise and Stuart overstay their welcome.

Everything changes as Amy and Sheldon await big news. Howard and Bernadette leave their kids, while Leonard and Penny keep a secret.

Bernadette and Howard leave their kids, Penny and Leonard try to keep a secret, Sheldon and Amy stick together, and Raj makes a new friend.

Brilliant physicists Leonard and Sheldon meet new neighbour Penny, who shows them that although they're smart, they know very little about real life.

Leonard volunteers to sign for a package to make a good impression on Penny, but things go terribly awry when he enlists Sheldon for help.

Trista. After losing her son and her marriage, Trista turned to food, reaching over 600 pounds. Ready to heal, she seeks Dr. Now's help.

Yolanda's immense size attracts the wrong kind of men. Desperate, she hopes that she will be approved for bariatric surgery with Dr. Procter.

Allie's polyamorous lifestyle is ruined by the gumball-sized bump above her eye. Later, Dr. Lee treats a patient with a shoulder lipoma.

Dr. Lee meets Jon, who suffers from a huge bump on his shoulder blade. Plus, April wants to get married but feels hideous due to her bumpy underarm.

Dr. Lee meets with Tobi, who has symmetrical bumps around her spine. Later, Dr. Tomassian learns how to remove a huge, floppy arm bump.

When her boyfriend and enabler falls ill, Lisa turns to Dr. Now for help with her food addiction. Can she summon the determination to turn her life around.

Meghan's wedding is in two weeks and she is panicking at the fitting because she does not recognise her dress. Can they fix it in time or will she have to buy a new gown.

Joan briefs the consultants on how to handle situations when a bride cannot make a decision without her mum or when a mum tries to take control.

Jennifer is on the search for a new gown after being pressured into purchasing a dress by her mum and step-mum. Plus, Lisa uses her fiancé as a style guide.

Bride-to-be Jessica has fallen in love with a dress that is unfortunately way over her budget. But can she be persuaded to compromise.

Mike and Carl get stuck working at the Renaissance Faire after their boss, Captain Murphy, gets dumped by Mike's mother.

Molly finds herself at a crossroads with her career and makes a huge decision to leave her teaching job to become a writer.

Poker In Front, Looker In Back. Molly recruits Joyce to spy on her next-door neighbour. Mike and the guys get together for a poker game and end up sharing their hopes and dreams.

Sheldon makes friends with his dorm neighbours. Meanwhile, George Sr. learns his job is in jeopardy.

When a new scientist, Dr. Lee, joins the lab, Sheldon is the odd man out. Meanwhile, Mary is given a lotto ticket.

Sheldon joins Dr. Linkletter and Dr. Sturgis on a science road trip, landing them in the middle of nowhere. Georgie continues to lie about his age.

Amy has a meltdown due to the pressure associated with winning a Nobel Prize. Raj and Howard try to relive the good old days.

Raj is worried people won't take him seriously in his own field after publishing a paper that suggests he may have discovered alien life.

Kripke has proof that Dr. Pemberton plagiarized his thesis, and Sheldon and Amy aren't sure whether they should turn him in or not.

Leonard is surprised when Beverly is kind to him on a visit, until he finds out the real reason she's there. Denise and Stuart overstay their welcome.

Everything changes as Amy and Sheldon await big news. Howard and Bernadette leave their kids, while Leonard and Penny keep a secret.

Bernadette and Howard leave their kids, Penny and Leonard try to keep a secret, Sheldon and Amy stick together, and Raj makes a new friend.

Brilliant physicists Leonard and Sheldon meet new neighbour Penny, who shows them that although they're smart, they know very little about real life.

Leonard volunteers to sign for a package to make a good impression on Penny, but things go terribly awry when he enlists Sheldon for help.

Molly needs to adjust her spending habits on shoes if she wants to maintain harmony in her marriage with Mike.

They Shoot Asses, Don't They? After being shot during a robbery, Mike wants to live each day like it's his last and tells Carl it's time for him to quit the police force.

Molly decides to take a break from writing her novel and accepts a job as a forklift driver at Vince's warehouse - with mixed results.

When Meemaw's gambling room is a success, she ends up with a suitcase of illegal cash. Missy starts a business, and Sheldon tries the stock market.

Sheldon gets an odd request from an old friend, while George and Mary are caught in the middle of Meemaw and Dale's breakup.

While Sheldon copes with the death of a hero, Georgie struggles with his big secret, and Missy wants to babysit.

Leonard is depressed to learn that Penny is dating someone. Encouraged by his friends and fellow scientists, he asks a colleague out on a date.

Sheldon gets fired and explores what life has to offer outside physics, leaving Leonard to take drastic action to snap his friend out of his funk.

Fearing he's wasting his time on Penny, Leonard makes a connection with Leslie. Meanwhile, Sheldon frets over a change to his hamburger routine.

Penny hosts a Halloween party, putting Leonard, Sheldon, Wolowitz and Koothrappali through a new test of their social skills.

When Wolowitz goes AWOL with one of her friends, Penny's recruited to fill in for him on the guys' Halo team.

Raj's parents set him up on a blind date, and when he discovers he can talk to her, she shows interest in Sheldon.

When they're invited to present at a physics conference, Sheldon's reluctance to share the credit leads to a tiff between him and Leonard.

Leonard and Sheldon each lie to avoid hearing Penny sing in a production of Rent. However, Sheldon's lie becomes a bit too complicated.

A master thief plots revenge after being double-crossed and his mentor murdered by one of his own crew following a 35-million-dollar gold heist.