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As their 20th anniversary approaches, Frankie begins to think that Mike may be tiring of her company and is purposely trying to avoid her.

Axl is shocked to discover that he and Sue are enrolled in the same class. Brick's therapist attempts to teach him how to reach out to other students.

Feeling guilty over not spending enough time with the kids, Frankie and Mike dedicate each day of a three-day weekend to one of their offspring.

Sheldon studies his family for a psychology project when their Thanksgiving dinner turns into a fight after George Sr. is offered a job in Oklahoma.

When Sheldon learns that stunted childhoods can turn people into outcasts, he tries to act his age. Meemaw and Dr. Sturgis's relationship is tested.

While Missy unknowingly becomes Sheldon's test subject, Georgie joins Mary's Bible study to spend more time with his crush, Veronica.

Leonard volunteers to sign for a package to make a good impression on Penny, but things go terribly awry when he enlists Sheldon for help.

Leonard is depressed to learn that Penny is dating someone. Encouraged by his friends and fellow scientists, he asks a colleague out on a date.

Sheldon gets fired and explores what life has to offer outside physics, leaving Leonard to take drastic action to snap his friend out of his funk.

Fearing he's wasting his time on Penny, Leonard makes a connection with Leslie. Meanwhile, Sheldon frets over a change to his hamburger routine.

Penny hosts a Halloween party, putting Leonard, Sheldon, Wolowitz and Koothrappali through a new test of their social skills.

When Wolowitz goes AWOL with one of her friends, Penny's recruited to fill in for him on the guys' Halo team.

Raj's parents set him up on a blind date, and when he discovers he can talk to her, she shows interest in Sheldon.

When they're invited to present at a physics conference, Sheldon's reluctance to share the credit leads to a tiff between him and Leonard.

Mike is upset with Frankie when he discovers that she set him up on an adult playdate with a new neighbour who shares the same interests.

Frankie and Mike worry that Axl isn't receiving any college acceptance letters. Meanwhile, Sue is determined to prove that smiling is contagious.

Axl and his friends make a profit on broken hearts. And, Mike accidentally sends a romantic text meant for Frankie to a co-worker at the quarry.

When Sheldon has to spend a few days in the hospital, he turns into the world's worst patient, and his behaviour takes a toll on everyone.

While Sheldon attempts to build a nuclear reactor to power the neighbourhood, Georgie is heartbroken when he learns that Veronica has a boyfriend.

Sheldon uses his new friendship with the school bully to boss Georgie around. Also, Missy steals Meemaw's makeup for Picture Day.

Leonard and Sheldon each lie to avoid hearing Penny sing in a production of Rent. However, Sheldon's lie becomes a bit too complicated.

With his friends knowing how sour he acts when sick and avoiding him as a result, Sheldon is nursed by Penny, who hasn't a clue what she's in for.

With Sheldon rattled after meeting Dennis, a teen physicist who's smarter than he is, the rest of the guys search for a way to eliminate the threat.

Sheldon finds himself booted from the gang's Physics Bowl team and replaced with Leslie, so he forms his own team hoping to prove he's superior.

When the delivery of a full-size prop of 1960's 'The Time Machine' causes Penny to miss work, she scolds Leonard about his sci-fi collectibles.

The gang fall for Sheldon's twin sister, and Leonard's plan to win her heart is derailed when Sheldon declares he'll decide who can date her.

Penny wants to throw a surprise party for Leonard, but Sheldon's indulgence at an electronics store throws her off-track.

Penny's breakup spurs Leonard to summon the courage to ask her out, and they both go to Sheldon for advice on their upcoming date.

Tightly wound Detective David Starsky is forced to partner with easy-going Detective Ken Hutchinson to solve a high-stakes narcotics case.

Cystem Shutdown! Gerard has nearly a hundred lumps varying in size all over his body. Eric has a large bump on his head that he calls his 'on/off button.

Mike is upset with Frankie when he discovers that she set him up on an adult playdate with a new neighbour who shares the same interests.

Frankie and Mike worry that Axl isn't receiving any college acceptance letters. Meanwhile, Sue is determined to prove that smiling is contagious.

Axl and his friends make a profit on broken hearts. And, Mike accidentally sends a romantic text meant for Frankie to a co-worker at the quarry.

Traci's confidence was destroyed after years of bullying about the bumps that have plagued her face for 20 years. Ravon has a unique dangling growth on his leg.

Krystal began overeating to shield herself with a protective layer after years of abuse. Once a means of protection, her eating habits might now kill her.

Gemma wants a sexy dress for her exotic beach wedding but her friends are set on princess-style. Fatema has her final fitting but is the gown modest enough.

Worlds collide as Alex looks for a black gown fit for Morticia Adams and Lucille Ball. Prashanthi's future brother-in-law asks to see a topless dress.

Mike is upset with Frankie when he discovers that she set him up on an adult playdate with a new neighbour who shares the same interests.

Frankie and Mike worry that Axl isn't receiving any college acceptance letters. Meanwhile, Sue is determined to prove that smiling is contagious.

Axl and his friends make a profit on broken hearts. And, Mike accidentally sends a romantic text meant for Frankie to a co-worker at the quarry.

When Sheldon has to spend a few days in the hospital, he turns into the world's worst patient, and his behaviour takes a toll on everyone.

While Sheldon attempts to build a nuclear reactor to power the neighbourhood, Georgie is heartbroken when he learns that Veronica has a boyfriend.

Sheldon uses his new friendship with the school bully to boss Georgie around. Also, Missy steals Meemaw's makeup for Picture Day.

Leonard and Sheldon each lie to avoid hearing Penny sing in a production of Rent. However, Sheldon's lie becomes a bit too complicated.

Howard uses a robotic arm for his own pleasure. Sheldon goes on a date with Amy Farrah Fowler, and Penny finds herself accompanying them.

With Sheldon rattled after meeting Dennis, a teen physicist who's smarter than he is, the rest of the guys search for a way to eliminate the threat.

Sheldon finds himself booted from the gang's Physics Bowl team and replaced with Leslie, so he forms his own team hoping to prove he's superior.

When the delivery of a full-size prop of 1960's 'The Time Machine' causes Penny to miss work, she scolds Leonard about his sci-fi collectibles.

The gang fall for Sheldon's twin sister, and Leonard's plan to win her heart is derailed when Sheldon declares he'll decide who can date her.

Penny wants to throw a surprise party for Leonard, but Sheldon's indulgence at an electronics store throws her off-track.

Penny's breakup spurs Leonard to summon the courage to ask her out, and they both go to Sheldon for advice on their upcoming date.

Frankie frets about Brick's field trip to Chicago. Meanwhile, Sue wants to find out if Axl's friend Darrin has feelings for her.

After the kids lie about a broken window, Frankie and Mike come up with a drastic way of dealing out consequences.

Frankie's sister, Janet, comes to the rescue and offers to help run the Heck household while Frankie studies for her dental assisting school finals.

Sheldon and Dr. Sturgis have a fight when Dr. Sturgis marks a question wrong on Sheldon's test. Mary takes over for Pastor Jeff when he's out sick.

Things spiral out of control when Sheldon boycotts his favourite bread company. Georgie consoles Veronica when she's dumped by her boyfriend.

Inspired by his hero, Albert Einstein, Sheldon tries his hand at the violin. Also, Mary and Meemaw secretly buy a pregnancy test.

Penny opens up to Sheldon after a less-than-stellar first date with Leonard, placing him in the uncomfortable position of having to keep a secret.

Seeing Penny with another guy sends Leonard back to Leslie Winkle, much to Sheldon's dismay.

Penny becomes addicted to an online game based on the world of Conan the Barbarian and persistently pesters Sheldon for advice.

Full of confidence following being named one of People's 30 to Watch Under 30, Raj hits on Penny and becomes impossibly arrogant.

An intervention is used to try to force Sheldon to overcome his fear of driving.

Sheldon and his friends are mystified when a younger undergraduate student is attracted to him.

When Sheldon bans Penny from the apartment, she decides to retaliate. Howard and Raj search for the America's Next Top Model house.

Sheldon wants to use an alternate version of rock-paper-scissors to help resolve conflicts. A girl Wolowitz has a major crush on falls for Leonard.

Catie raises a delicate topic with Josh. Paula's family arrives from Brazil. Ashia gets stuck in an intervention. Edward and Marissa's date goes awry.

David is back to see Dr. Lee after she spotted a suspicious growth under his eye. And, Alan has a growth on his bicep but is terrified of doctors.

Frankie frets about Brick's field trip to Chicago. Meanwhile, Sue wants to find out if Axl's friend Darrin has feelings for her.

After the kids lie about a broken window, Frankie and Mike come up with a drastic way of dealing out consequences.

Frankie's sister, Janet, comes to the rescue and offers to help run the Heck household while Frankie studies for her dental assisting school finals.

Tim has a massive growth on his back that affects his ability to work and socialise. Meanwhile, a mother-daughter duo has bonded over their bumps.

Isaac helped raise his siblings after his mother suffered a stroke. While learning to cook for his family, he picked up life-changing eating habits.

First-timer Rebecca is set on a glam gown but falls for her first dress, a princess gown picked by mum. Rhia wants a dramatic dress with cleavage - but not mum.

Our Dress Has To Go Viral. Amanda has been obsessing over a Randy Fenoli dress, but will it live up to the hype? Kindra and her pastor mother can't agree on a suitable dress.

When Mary's faith is shaken by a tragedy in the community, Sheldon becomes an unlikely ally.

When George Sr. asks Sheldon to keep a secret from Mary, the stress of not being honest drives Sheldon to hide out at Tam's for his first sleepover.

Dr. Sturgis recommends Sheldon and Missy for a university research study on twins, and Mary is unhappy when the test results go to Sheldon's head.

Mary clashes with Sheldon's drama teacher Mr. Lundy over plans for a Halloween haunted house fundraiser for the church.

Sheldon gets into trouble with fellow child genius Paige at the Science Museum, while George Sr. is forced to play therapist to Paige's parents.

When Meemaw gives Sheldon his first video game, it takes over their lives. Meanwhile, George Sr. gets jealous when Georgie bonds with Herschel.

Sheldon studies his family for a psychology project when their Thanksgiving dinner turns into a fight after George Sr. is offered a job in Oklahoma.

When Sheldon learns that stunted childhoods can turn people into outcasts, he tries to act his age. Meemaw and Dr. Sturgis's relationship is tested.

A VHS tape inspires Sheldon to not give up on his and Amy's theory. Bernadette turns into a pageant mom over Howard's Magic Castle audition.

Penny and Leonard organise a paintball game that results in mayhem. Raj catches Anu with her ex, and Stuart doesn't want to move in with Denise.

Penny's ex, Zack, and his wife want a baby, but when Zack is infertile, they ask Leonard to help. Raj attempts to mend things with his ex-fiancée.

Sheldon and Amy's theory is proven by two physicists, who then try to kick Amy off the Nobel nomination. Bernadette has a big success at work.

Sheldon helps Bernadette and Howard navigate bureaucratic paperwork. Leonard is disappointed when his friends exclude him from a scientific project.

Penny tries to seduce an abstaining Leonard to ruin his 'donation' for her ex-boyfriend and his wife. Raj's cancelled bachelor party takes a turn.

The gang finds out Wil Wheaton hosts a celebrity Dungeons and Dragons game. Deception and betrayal are the path to make it to the one open seat.

While Bernadette is away and Howard is in charge of the kids, Sheldon finds a book on experimenting on kids. The guys plus Amy make a day of it.

Pemberton and Campbell charm America, so Sheldon and Amy bring Nobel laureates Kip Thorne, George Smoot and Frances Arnold to their side.

Amy has a meltdown due to the pressure associated with winning a Nobel Prize. Raj and Howard try to relive the good old days.

Raj is worried people won't take him seriously in his own field after publishing a paper that suggests he may have discovered alien life.

Kripke has proof that Dr. Pemberton plagiarized his thesis, and Sheldon and Amy aren't sure whether they should turn him in or not.

Leonard is surprised when Beverly is kind to him on a visit, until he finds out the real reason she's there. Denise and Stuart overstay their welcome.

Everything changes as Amy and Sheldon await big news. Howard and Bernadette leave their kids, while Leonard and Penny keep a secret.

Bernadette and Howard leave their kids, Penny and Leonard try to keep a secret, Sheldon and Amy stick together, and Raj makes a new friend.

Brilliant physicists Leonard and Sheldon meet new neighbour Penny, who shows them that although they're smart, they know very little about real life.

Leonard volunteers to sign for a package to make a good impression on Penny, but things go terribly awry when he enlists Sheldon for help.

Leonard is depressed to learn that Penny is dating someone. Encouraged by his friends and fellow scientists, he asks a colleague out on a date.

Sheldon gets fired and explores what life has to offer outside physics, leaving Leonard to take drastic action to snap his friend out of his funk.

Fearing he's wasting his time on Penny, Leonard makes a connection with Leslie. Meanwhile, Sheldon frets over a change to his hamburger routine.

Brittany has been called a monster due to a genetic condition that causes head-to-toe bumps. Tamyra has skin so thick she shaves the bottom of her feet for relief.

Jaclyn has a lump on the back of her head that causes her emotional distress. Shane has a growth between his eyes that could put him in danger at his electrician job.