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Sheldon meets Amy's mum and comes to the realisation he no longer wants to see Amy, and Leonard realises everyone is in a relationship except for him.

When Raj's sister has a one-day layover, he forbids the others from hooking up with her, unaware she and Leonard already did long ago.

Love, Lies, And La Dolce Vita. Jessy is ready to risk it all in Italy. Andi has doubts about moving down under. Jon and Ally hide her pregnancy. Niles plans to head back to Ghana.

Gerald returns to see Dr. Lee and a hand specialist about a huge, intrusive bump on his finger. Vinnie has an embarrassing birthmark on his neck.

Frankie tasks Mike into having a talk with Brick to discuss dating etiquette. Sue tries to work up the courage to tell Sean her feelings for him.

Axl gets sick and tired of having Mike tell him how to run his life. Frankie swears that she's seeing something mysterious flying through the house.

Frankie forces Brick to ask Cindy to the prom. Lexie talks a clueless Axl into giving Sue a belated 21st birthday present.

Lee Nose Best! Tony has large growths on his nose that impair his breathing. Can Dr. Lee help? And, Marie has an unsightly lump on her forehead that makes her a hermit.

Steven And Justin's Story Part 2. After a year on a weight loss programme, Steven is non-compliant, and Justin focuses on a new career instead of his diet. Time is running out.

In just 4 weeks, bride-to-be Lorna emigrates to the USA to marry her dream woman. With her partner wearing a suit, can Jo and Al find a dress to wow the crowd.

Marie doesn't wear dresses, and planned a country and western themed wedding, so she can wear jeans! Can Jo and Al find her the perfect confidence-boosting dress.

Alison wants Jo and Al to dress her on the big day - but they are already booked. They hand over the reins to protégé Lacey - is she up to the challenge.

Unhappy that school funds are going toward football rather than academics, Sheldon decides to run for class president.

Georgie is thrilled when Veronica stays at the Coopers' for a few days. Meanwhile, Meemaw and Dr. Sturgis celebrate their one-year anniversary.

The Coopers help a broken-hearted Pastor Jeff through a rough patch in his marriage. Meanwhile, Sheldon pressures church members for donations.

Sheldon invites the entire school to a party for the Nobel Prize announcements. Meanwhile, Meemaw learns more about Dr. Sturgis's past.

After Dr. Sturgis experiences a nervous breakdown, Mary worries Sheldon is headed down a similar path. Georgie finds he has a knack for sales.

Without Dr. Sturgis's university class, Sheldon takes his education into his own hands. Mary helps Pastor Jeff avoid temptation with his girlfriend.

Sheldon leaves town after a fight with Meemaw and his parents. Meanwhile, Georgie tries to impress Veronica with his new business venture.

Sheldon's obsession with The Lord of the Rings leads to an unhealthy habit. Missy asks her dad to teach her how to play catch.

Penny's criticism of Wolowitz's romantic life pushes him into depression and AWOL for a fighting robot battle the guys are depending on him for.

Looking to get friendly with Barry Kripke to gain access to a piece of high-tech lab equipment, Sheldon develops a flowchart process to make friends.

When Sheldon loans money to Penny so she can pay her rent, it leads to Leonard coming face-to-face with her ex, Kurt.

A visit from Leonard's mother ends up bringing him and Penny closer.

Paintball leads to a squabble between Sheldon and Penny as well as romance between Howard and Leslie.

The gang is thrilled to see Summer Glau is also aboard their train to San Francisco. Sheldon frets over having forgotten a paper he wants to present.

Penny's business selling hair accessories out of her apartment gets out of hand when an over-caffeinated Sheldon takes charge.

Penny feels threatened when another sexy woman moves into the apartment building and angered when she senses the guys are being taken advantage of.

A fellow comic book enthusiast's hitting on Penny leads to Leonard, Raj and Howard going to a bar's Ladies' Night.

Leonard and Raj take Wolowitz to Las Vegas to help him get over his break-up. Sheldon locks himself out and has only one other place to stay: Penny's.

Stuart asks Leonard's advice for a date with Penny. Wolowitz realises there's an error in a toilet he designed for the International Space Station.

The guys receive a prestigious offer to work over the summer at the North Pole, and Penny's resultant behaviour leaves Leonard unsure if he should go.

Discovering Leonard, Raj and Howard fudged the results of his Arctic research expedition, a disgraced Sheldon heads home to Texas.

Sheldon and Howard wager comic books over a cricket's species. Meanwhile, a less-than-perfect romantic night agonizes Leonard and Penny.

Howard takes Raj along to check out the Goth dating scene. Sheldon uses chocolate as part of a behaviour modification experiment on Penny.

Facing a return to India, Raj needs a job desperately enough to consider working for Sheldon. Howard becomes a third wheel to Leonard and Penny.

Sheldon looks forward to squaring off against a Star Trek actor in a fantasy card game tournament. Wolowitz cashes in on an old pact with Leonard.

Hoping to fit in with Penny's football-loving friends, Leonard gets tutored in the sport by Sheldon. Raj is furious over the loss of his patang.

Leonard and Penny's first big fight sees Sheldon playing mediator due to childhood trauma that means he can't be around loud verbal conflicts.

Barry Kripke pranks Sheldon during his spot on NPR, leaving him wanting vengeance. Bernadette pressures Wolowitz to define their relationship.

Bob suffers from mysterious open-wound sores all over his body. Virginia can't wait to have her lump removed. Tom is desperate to find a cure for his itchy skin.

Steven's bump is so large, his daughter thinks he is growing a monster on his back. Ethan suffers from an irritating rash in an awkward place on his body.

John lost his sight at a young age and soon after began growing lumps on his body. Lynette has hundreds of pebble-sized bumps on her arms, chest, and belly.

Cystem Shutdown! Gerard has nearly a hundred lumps varying in size all over his body. Eric has a large bump on his head that he calls his 'on/off button.

Traci's confidence was destroyed after years of bullying about the bumps that have plagued her face for 20 years. Ravon has a unique dangling growth on his leg.

Chloe is dress shopping with her mum, but worries her voice won't be heard. And, Diane has waited 25 years to go dress shopping for her wedding to Kathy.

Since meeting at a bariatric rehab centre in 2006, Lee and Rena's weight has skyrocketed. The couple now makes a second attempt to save their lives.

Marianna has lost 5 stone for her wedding, yet still lacks confidence about her appearance. Jo and Al find a solution to make her feel amazing on the big day.

Helen never wears dresses and is anxious about choosing the right gown. And, Jo and Alison manage a last-minute refit for bride Aimee after surprise weight loss.

Third-time bride Janine hopes to finally find a gown with a wow factor but will her mum approve? Jacqui worries that her chosen dress can't contain a baby-bump.

After being released from the psychiatric hospital, Dr. Sturgis unexpectedly breaks up with Meemaw.

A Parasol And A Hell Of An Arm. A church carnival leads Missy to try out for the baseball team. Meanwhile, Meemaw struggles after her breakup with Dr. Sturgis.

Sheldon starts the first internet flame war, and Meemaw is unhappy when George spends time with her new boyfriend.

The university tries to recruit Sheldon, through George. Georgie gets a job working for Meemaw's new boyfriend. Mary decides to rid her home of greed.

Mary gets Pastor Jeff involved when Sheldon isn't invited to Billy's birthday party. George, meanwhile, has 'male-bonding time' with Dr. Sturgis.

Sheldon fakes being sick to avoid a swim test at school. Meanwhile, Dr. Sturgis spies on Meemaw's new boyfriend.

Georgie and Fagenbacher go head-to-head when Fagenbacher tries to sabotage Georgie's attempt to honour his dad.

Georgie's plan to get on the news sparks a feud between Mandy and a rival weathergirl. Meanwhile, Mandy tries to use the conflict to help her career.

Penny seeks Sheldon's help to better comprehend Leonard's physics work. Wolowitz sees green when Leonard invites Bernadette to watch an experiment.

A Christmas visit from his mother has Leonard discovering she's kept a lot of news from him that she shares with Sheldon.

Leonard is aghast to find out that Penny believes in psychics. Sheldon tries to assist Koothrappali in picking up a girl at a university party.

A robbery of their apartment sees Leonard and Sheldon call on their friends to devise a security system.

Stuck on the solution to a physics problem, Sheldon tries different methods to change his thinking, including working at The Cheesecake Factory.

When Leonard is offered a trip to Switzerland on Valentine's Day to see a particle accelerator, he must choose between taking Penny or Sheldon.

An appearance in traffic court comes at the worst possible time for Sheldon, the same day Stan Lee is appearing at the comic book store.

The guys go to a garage sale and find a ring from the Lord of the Rings films, and the rare find threatens their friendship.

Sheldon's fear of speaking in front of large groups threatens his ability to accept an award, so the gang tries to help him prepare for the big night.

Sheldon squares off at the bowling alley against nemesis Wil Wheaton. Leonard's miffed over Penny's response when he says, 'I love you.

Following Leonard and Penny's break up, Sheldon tries to hide from Leonard and the gang that he had a friendly spaghetti dinner at Penny's.

Sheldon hosts a visiting female physicist, but her intelligence seems matched by her libido.

A squabble over the thermostat setting leads to Leonard going over to Penny's and recounting the story of how he met and moved in with Sheldon.

Howard and Raj set Sheldon up on an Internet dating site. Penny discovers that she can't go back to dating dumb jocks after dating Leonard.

Howard uses a robotic arm for his own pleasure. Sheldon goes on a date with Amy Farrah Fowler, and Penny finds herself accompanying them.

Sheldon calculates that he'll be dead before technology exists to download his consciousness into a robot, so he goes on a healthy-living binge.

Sheldon breaks up with Amy Farrah Fowler, and the guys worry when he starts replacing her with cats.

Wolowitz is embarrassed when a secret of his is revealed, and Sheldon and Raj battle at work.

Sheldon meets Amy's mum and comes to the realisation he no longer wants to see Amy, and Leonard realises everyone is in a relationship except for him.

When Raj's sister has a one-day layover, he forbids the others from hooking up with her, unaware she and Leonard already did long ago.

Ed Gamble hosts captains and Richard Ayoade and Joanne McNally defend wild views. Phil Wang wants Britain run by Chinese people.

Dara Ó Briain makes sense of world events - kind of - with guests Rhys James, Angela Barnes, Neil Delamere, Ed Byrne, Finlay Christie and Zoe Lyons.