Discovery Life Channel

With lumpy lipomas and cysts-a-plenty, Dr. Lee and her staff will have their hands full during one of their busiest days of the year.

Christmas is in full swing at Dr. Pimple Popper HQ with patients galore, but this year, Dr. Lee and her staff are partaking in a merry task to re-create classic Christmas movie scenes with pimple-y twists for holiday cards for their patients.

Stacey's shoulder growth prevents her from being the playful teacher she once was; Matthew worries that his mysterious shin rash may be dangerous.

Brittany has been called a monster due to her genetic condition that causes head-to-toe bumps; Leonardo has a fist-size growth on his head, but he is terrified of doctors; Tamyra has skin so thick that she shaves the bottom of her feet for relief.

Jaclyn has a lump on the back of her head that causes her emotional distress; Shane has a growth between his eyes that could put him in danger at his electrician job; Brittany has seen multiple doctors about the sores on her body with no answers.

Professor Murray Brilliant from the University of Arizona researches a radical new medical theory by traveling to Africa to test hundreds of people with leprosy and albinism.

The daily lives of three sets of conjoined twins reveal difficulties they endure.

A woman believes her neighbors want to kill her; a man is near death after an arrow pierces his chest; two women with swollen abdomens refuse to explain the cause of their pain.

A circus sword-swallower suffers from a persistent case of hiccups; a mother and daughter mysteriously collapse in the ER; a woman loses control of her legs at her daughter's graduation.

An ER doctor's friend arrives at the hospital combative and out of control; a cyclist's throat is torn open when a driver opens a car door in her path; a nursing student is found passed out on the hospital floor.

A young girl is mysteriously paralyzed from the waist down; a young man complains of a splitting headache; a bride-to-be has appendicitis on her wedding day.

Gang warfare and a high population of sick patients keep medical center workers on the move in Los Angeles.

Trauma patients flood the Tampa General Hospital during Gasparilla Day -- the city's version of Mardi Gras.

The work of the staff at Baylor University Medical Center in Dallas includes a rodeo champion who was trampled by a bull.

University of New Mexico Hospital staffers treat victims of crime, accident and illness.

Mothers and their teenage daughters unexpectedly find themselves pregnant at the same time.

Four mothers and four daughters who are all pregnant at the same time.

Tensions run high at Lorna and Chae's baby shower; Kim's boyfriend violates probation; Nicole is newly single; Lemhele races to the hospital to give birth.

Two families welcome a new child; two defiant boyfriends return while another slips away.

A pregnant woman suffers strokes and a heart attack.

A woman experiences severe abdominal cramps while on a boat in the middle of the open water.

A high-school student thinks that her weight gain and fatigue are from eating poorly and working too much.

After failing two pregnancy tests, a woman is shocked to learn the truth about her symptoms; a woman gets a surprise after having gastric bypass surgery.

An unknowing mother goes into labor in her bathroom; a woman's water breaks years after being told that she is unable to get pregnant.

A teenager believes that she is unable to bear children after having an aggressive chemotherapy treatment; a nursing student learns she is pregnant after an emergency appendectomy.

A new mother struggles to lose her baby weight; a mother gets a surprise after having her tubes tied.

A teacher's aide fails to recognize the signs of pregnancy; a 40-year-old is shocked to learn that she is pregnant.

A pregnant woman suffers strokes and a heart attack.

A woman experiences severe abdominal cramps while on a boat in the middle of the open water.

A high-school student thinks that her weight gain and fatigue are from eating poorly and working too much.

After failing two pregnancy tests, a woman is shocked to learn the truth about her symptoms; a woman gets a surprise after having gastric bypass surgery.

An unknowing mother goes into labor in her bathroom; a woman's water breaks years after being told that she is unable to get pregnant.

A teenager believes that she is unable to bear children after having an aggressive chemotherapy treatment; a nursing student learns she is pregnant after an emergency appendectomy.

A new mother struggles to lose her baby weight; a mother gets a surprise after having her tubes tied.

A teacher's aide fails to recognize the signs of pregnancy; a 40-year-old is shocked to learn that she is pregnant.

Tensions run high at Lorna and Chae's baby shower; Kim's boyfriend violates probation; Nicole is newly single; Lemhele races to the hospital to give birth.

Two families welcome a new child; two defiant boyfriends return while another slips away.

Most of the extreme weight on Tracey's body resides in her shockingly misshapen legs, which are massive with severe lymphedema, and gastric surgery is her only chance of survival; Brenda and Melissa prepare for skin removal surgery.

Bedridden Marla is so heavy she cannot stand up; she must face the hard truth about her condition and understand the toll it takes on her supportive family.

Chay has eaten his way to 600 pounds to cope with the emotional turmoil of his childhood; he loses his emotional support and searches for new strength to take control of his life.

At 24 years old and over 600 lbs, Megan lives at home with her mom, who cooks for her since Megan can't do much on her own; Megan must travel to Houston to meet Dr Now and change her eating habit or her life may end before it ever begins.

Ashley is 24 and lives alone; her only sources of comfort are food and the relationships she has online; but not a single one of her profiles is real; Ashley learns that Dr Now isn't someone she can lie to like her online friends.

For 23 years, Leneatha has worked as a pharmacy tech at a local hospital; now, she has a young daughter to support, but she's so big that it's hard to move; if Dr Now can't help her stop eating, losing her job could be the least of her worries.

At nearly 1,000 pounds, Samantha is dangerously close to dying; to make matters worse, she's paid to eat by making videos online; if Samantha doesn't overcome her toxic relationship with food, she worries she will leave her daughter motherless.

Nothing means more to Chris than his relationship with his daughter, Zoey, but now he feels he is failing her as his weight gain begins to limit his mobility.

Patrick's weight has never been a bother, but now he's so big that it's getting in the way of his relationship with his daughter; if he wants to see her graduate high school, he'll have to reverse course.

Krystal S. has finally met the man of her dreams, but she won't let herself marry him until she can be sure that she won't become bedridden and force him into the role of caretaker.

Patrick's weight has never been a bother, but now he's so big that it's getting in the way of his relationship with his daughter; if he wants to see her graduate high school, he'll have to reverse course.

Krystal S. has finally met the man of her dreams, but she won't let herself marry him until she can be sure that she won't become bedridden and force him into the role of caretaker.

Nothing means more to Chris than his relationship with his daughter, Zoey, but now he feels he is failing her as his weight gain begins to limit his mobility.

Steven Assanti weighs nearly 800 pounds and his brother Justin almost 600 pounds, and although they can't stand each other, their father packs up the family to travel across the country and seek help.

Penny returns to Maryland believing she can lose weight; Tara continues to lose weight and is dating for the first time.

Melissa, mother of four, finds herself feeling overwhelmed due to a rocky marriage and an unexpected pregnancy; when Ashley's weight-loss journey hits a wall, she sets out to find new inspiration to get herself back on track.

Gastric surgery freed Brittani from her housebound life, but to achieve her ideal body she'll have to endure two more painful surgeries; Sean's super-obesity nearly killed him.

Surgery enables Teretha to return to family in Detroit, but it soon threatens to undo all her progress; Chad is back on the road, but his old diet is a risk.

After losing 250lbs, Nikki is on her way to skin surgery, but when a close friend dies from weight loss surgery, Nikki's progress is derailed by fears.

Devastated by the sudden loss of her son, Dottie's weight loss journey is in danger of going off track; June embarks on a plan to win approval for skin surgery; Melissa, Jessica and Matt prepare for skin removal surgery.

Abi was struggling with his weight before a fluke accident left him mostly paralyzed; bedbound for seven years since then and topping 700 pounds, Abi's only hope for a future with his wife is to get Dr. Now's help to lose weight.

When a regular trip to the grocery store turns into an emergency for the EMTs, Delana must admit how badly she needs Dr. Now's help to lose weight; hopefully her road to recovery will lead her to reconcile with the daughter she's grown apart from.

At age 58, Rose had almost given up and eaten herself to death, but it turned out her family needed her too much for her to go; now she has more than 400 pounds to lose if she wants to get healthy for them, and she's determined to do it.

When a regular trip to the grocery store turns into an emergency for the EMTs, Delana must admit how badly she needs Dr. Now's help to lose weight; hopefully her road to recovery will lead her to reconcile with the daughter she's grown apart from.