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When a 23-year-old Marine dies in his bedroom, doctors initially believe a heart attack is to blame; when arsenic is found in his organs, his wife is charged with murder; a sharp attorney and toxicological testing uncover the truth.

When an 18-year-old girl is abducted while talking on a pay phone, forensic evidence found on her clothing points police in the direction of a suspect who shockingly confesses that he didn't act alone.

In the story of a Los Angeles kidnapping, ransom and murder ring, retired scientists use sonar equipment to locate victims at the bottom of a reservoir.

Patients at the VA Hospital in Clarksburg, W.Va., keep dying after experiencing shockingly low blood sugar levels; an investigation into their deaths reveals an overnight nurse was injecting patients with lethal doses of insulin.

A 70-year-old retired veteran is found dead on his boat after a bad sea storm; detectives discover he was killed during an attempted robbery after winning $400 in keno.

The murder of teacher's aide leaves a hole in the heart of her small community; as rumors spread about suspects, the actual perpetrator slips further away.

A husband was shot and killed, forensic psychiatry helped the wife to remember the details for what happened.

The body of a 16-year-old girl is discovered nine months after her disappearance; forensic scientists find clues that paint a virtual portrait of her killer.

A young woman falls to her death in what appears to be a tragic accident; a forensic exam of photos taken at the scene tells a different story.

Haunted by her mother's long-ago disappearance, a woman undertakes an investigation of her own and stumbles upon a dark family secret.

An Alaskan trooper finds a woman's body beside a frozen road, but evidence is scant even after a suspected murder weapon is found.

Police link a clump of hair discovered in an isolated area with a woman who disappeared 20 years ago.

A news anchor is shot to death outside her home in an apparent crime of passion by a fan; a police dog tracks the scent of the killer back to the crime scene.

A fire, caused by an unattended cigarette, kills the estranged wife of a police officer; forensic scientists discover that the cause is far more complicated.

A trio of men, responsible for several bank robberies, leaves no evidence behind; forensic scientists help catch them by looking at the criminals' posture and clothing.

When a woman's bone marrow test reveals arsenic poisoning, investigators try to determine if it is due to groundwater contamination or something more sinister.

A missing bank president's body is found floating in a lake; the duct tape used in binding him to a chair helps solve the crime.

A husband was shot and killed, forensic psychiatry helped the wife to remember the details for what happened.

The body of a 16-year-old girl is discovered nine months after her disappearance; forensic scientists find clues that paint a virtual portrait of her killer.

A young woman falls to her death in what appears to be a tragic accident; a forensic exam of photos taken at the scene tells a different story.

Haunted by her mother's long-ago disappearance, a woman undertakes an investigation of her own and stumbles upon a dark family secret.

The robbery and brutal murder of an elderly couple goes unsolved for 10 years; a forensic scientist makes history when he solves the crime.

A man is charged with the murder of a wrestling champion; six years later, a forensic animator testifies on his behalf.

A 19-year-old girl is found dead in her car in what appears to be a suicide; police discover that the victim was involved in a love quadrangle, giving several people motive to kill.

Fifteen years after a man disappears, using a metal detector, police find evidence which proves what had happened.

The body of a young California co-ed under an isolated interstate ramp sets off an investigation; San Diego police have no idea who would want her dead, but they discover a tiny, unique fiber on the victim's clothing.

Police become suspicious of a man who reported his wife missing 15 years after doing the same thing with his first wife.

While investigating the case of a Colorado hunter shot three times and killed, police suspect two murder weapons, and two killers, but forensic evidence points them closer to home.