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Detectives and forensic experts recount cold cases solved using familial DNA testing.

After decades of searching, Ohio detectives use ground-breaking technology to hunt down the man who abducted and sexually assaulted a 19-year-old woman.

A woman gets attacked while on her way home in 1997 but the suspect wasn't caught until 20 years has passed.

In 1974 a community in Montana was rocked by the sexual assault and murder of a young girl. The case went unsolved for 46 years before advances in DNA technology found the culprit.

A woman gets attacked while on her way home in 1997 but the suspect wasn't caught until 20 years has passed.

In 1974 a community in Montana was rocked by the sexual assault and murder of a young girl. The case went unsolved for 46 years before advances in DNA technology found the culprit.

Investigators attempt to get to the bottom of a murder in an affluent, once-peaceful neighborhood.

Years after a woman is murdered in the back of her comic book store, new evidence is discovered that sends the investigation in a surprising direction.

Hiker Meredith Emerson goes missing on Georgia's Blood Mountain on New Year's Day 2008. Could her disappearance be linked to two cases with similar circumstances? Dennis Murphy reports.

The case of a husband who had simply vanished. On the surface, it didn't make sense: He had a wife, a lucrative job, a daughter he loved. But he also had a secret.

Young nursing student Michelle Le had disappeared. Something drew her out to her car, right before cameras caught the car peeling away. Next, there was a series of strange texts. It is discussed whether Michelle was missing or murdered.

Lester Holt spends two nights locked up inside the largest maximum security prison in America, the notorious Louisiana State Penitentiary, also known as Angola.

When a college student is found dead after a party, his mother is determined to try to find out what happened. With the help of a new friend, she manages to get the case in front of a jury.

A bank president's murder; a double agent's death. Also: an aspiring photographer goes missing; an escape artist is on the loose.

Recently uncovered pages from John Hinckley Jr.'s diary, which he began writing after he was arrested for trying to assassinate President Ronald Reagan, are revealed.

Keith Morrison reports on a dramatic undercover operation in Palm Beach, Florida to save a wife and mother who had no idea she was in danger.

A woman gets attacked while on her way home in 1997 but the suspect wasn't caught until 20 years has passed.

In 1974 a community in Montana was rocked by the sexual assault and murder of a young girl. The case went unsolved for 46 years before advances in DNA technology found the culprit.

A man convicted of murder in 1985 finally gets his justice 18 years later after DNA evidence pointed towards a different suspect.

When a woman is found dead in her home, detectives are left with more questions than answers.

A man convicted of murder in 1985 finally gets his justice 18 years later after DNA evidence pointed towards a different suspect.

When a woman is found dead in her home, detectives are left with more questions than answers.

A mother survives a shooting attack in her home.

After Johnny Altinger disappeared, investigators followed a trail of clues that led them to a young director. Detectives were concerned that the case was a fake perpetrated by a skilled storyteller. It turned out that the script was darker than everyone knew.

Lawyer John Sutton and his wife Susan are murdered in their million-dollar Florida home.

Convicted murderer Drew Peterson speaks out about the murder of his third wife and the disappearance of his fourth wife. Insiders close to the case speak out, including Stacy Peterson's sister.

A college student is found murdered in a residential neighborhood. As police search for the truth, they are stunned to learn that one of their own might be involved.

The hunt for a serial killer; ghost blimp sightings. Also: a man seeks his twin brother; a camping couple are murdered in Washington state.

An investment scheme destroys a couple's dream; an infant is kidnapped in Florida; dogs predict when their owners are going to have seizures; a psychic helps the police.

Rocker Bobby Fuller's death; Ouija-board claims. Also: a woman seeks her twin; a husband is convicted of murdering his wife, but the wife's parents believe he is innocent.

A robber escapes from prison; Amelia Earhart's disappearance; a 17-year-old's death is a ruled a suicide but the family believes otherwise; a shootout at a bar.

A man goes on the lam after murdering his former fiancée; a mother suspected of killing her daughter is murdered. Also: profiling five separated siblings; claims concerning a man purported to have healing powers.

A man convicted of murder in 1985 finally gets his justice 18 years later after DNA evidence pointed towards a different suspect.

When a woman is found dead in her home, detectives are left with more questions than answers.

In the hope of finding her estranged biological mother, a woman went through a genealogy test. In a shocking twist, her DNA proved to be useful in unlocking a cold case of an unidentified murder victim over forty years ago.

In 1973, two young girls are found murdered in the Welsh village of Llandarcy. The killer's identity remains a mystery until 2002.

In the hope of finding her estranged biological mother, a woman went through a genealogy test. In a shocking twist, her DNA proved to be useful in unlocking a cold case of an unidentified murder victim over forty years ago.

In 1973, two young girls are found murdered in the Welsh village of Llandarcy. The killer's identity remains a mystery until 2002.

Decades after Kathy Heckel mysteriously vanished, one detective believed he could solve the case.

A successful businesswoman and mother of three is found shot in her office; the investigation into her death leaves a family divided.

Michelle Mockbee met her husband at the warehouse where they both worked. It was also where she met an untimely death. Security footage led police to a suspect but when it appeared justice had been served, a scandal turned the case upside down.

A murdered Las Vegas resident is found in Lake Mead; a therapist employs a special healing technique on ailing animals; parents seeks their son's killer; a murder mystery from Twin Falls, Idaho.

A purportedly haunted house in Nevada; a drug dealer is sought by the FBI; a woman seeks her birth parents to learn her family's medical history; a man accused of committing child abuse is wanted by the police.

Sightings of strange lights in Marfa, Texas. Also: a woman uses arsenic to secretly poison her family; US marshals and the FBI track a drug dealer and murderer; a woman and her son vanish.

The police search for a rapist; a woman poisons her husband and absconds with her son; an antique dealer wants to return a unique find to its rightful owner; a family tries to reunite.

A train hits two teenagers in Arkansas; a rapist flees from the police while out on bail; a woman is shot to death in her car. Also: the search for a famous aviator.

When a single mother of three vanishes, police discover she may have been living a double life.

Authorities first believed Mike Williams drowned or was possibly eaten by alligators until his mother pressed law enforcement to reopen the case. Dennis Murphy reports.

This wasn't just going to be any Halloween party. It was the big event of the season. Chelsea had her costume ready, sewed the leaves on herself. She dressed as be Poison Ivy but she never imagined she would encounter real evil that night.