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Dara Ó Briain introduces an end of series special featuring a look back at the best bits, hilarious out-takes and some brand-new material.

The Curious Case Of The Pooting Cyst. Diane has thousands of tumours all over her body that have ruined her life. Plus, Will is worried his shoulder lump will be ripped open at work.

Sheldon and his dad dine with President Hagemeyer and a university benefactor. Also, Dale and his ex-wife invite Meemaw to their son's wedding.

My Giant Nose Is Killing Me. Roger has huge growths on his nose that drip pus, attract flies and make breathing difficult. Plus, two sisters share many undiagnosed face bumps.

What's a bride to do when her entourage is bossy instead of helpful? Tenisha wants lots of bling, but her bridesmaids insist on other styles.

At over 700lbs, Brianne is on a weight-loss journey to save her own life. But she faces another shock when her husband's health suddenly deteriorates.

Debbie's twins prove hard to please when searching for the perfect dress. And, can Kirstie convince her mum to blow the budget on the dress of her dreams.

Emotions run high when Joma can't find the perfect dress that compliments her figure. Plus, insecure bride Claudia wants a gown to boost her confidence.

Bride Lukoka struggles to make a decision on two very different dresses. Plus, at her final fitting Whitney realises she's fallen out of love with her dress.

Fishtail Show. Miki is torn between a figure hugging fishtail and a romantic princess gown. A slim fitted style threatens Michelle's dreams of a big sparkly dress.

With the house feeling crowded, Molly decides to have a yard sale, while Mike and the guys take Carl on a fishing trip.

When Mike gets sick for Thanksgiving, Molly is excited that she won't have to cook until Vince invites his brother, Frankie, to town.

Molly encourages Mike to pursue a detective position on the force, but the stress of taking the qualification exam starts to take a toll.

Sheldon's first day of college is derailed by his new philosophy teacher. Mary and Brenda live vicariously through Missy's first day of middle school.

Meemaw takes matters into her own hands when Sheldon's philosophy teacher, Professor Ericson, sends him into a tailspin.

Sheldon and his dad dine with President Hagemeyer and a university benefactor. Also, Dale and his ex-wife invite Meemaw to their son's wedding.

Sheldon and the gang celebrate his birthday and he's surprised by a special guest.

Howard reconsiders entering into a legal partnership with Leonard and Sheldon, and the women offer Raj dating advice.

Sheldon shocks Amy with a startling revelation after she buys him a laptop. Raj throws Leonard and Howard under the bus when they lie to their wives.

Sheldon shares a secret about Leonard when the two go on a weekend trip with Penny and Amy; Raj goes all out with pregnancy gifts.

During a group get-together, a minor argument between Sheldon and Leonard turns into a heated debate, leaving the rest of the gang to choose sides.

Sheldon stays with Bernadette while the rest of the gang attends an event where they run into Penny's former boyfriend and meet Raj's girlfriend.

Sheldon hires Stuart to spend the day with Amy. Meanwhile Leonard's mother visits, and Penny just can't seem to connect with her.

Leonard's recently divorced parents roll into town, as does Sheldon's holy-roller mother, and all hell breaks loose.

Mike dresses as Santa but feels more like the Grinch when he can't contain his frustrations over Molly's Christmas spending.

In an effort to boost their chances of getting pregnant, Molly encourages Mike to join her in giving up caffeine and eating healthier.

Mike risks losing his eyebrows when he starts construction on the basement for he and Molly, while Carl invites Samuel to move in with him.

Sheldon campaigns to become Dr. Linkletter's lab assistant. Georgie enlists the drama teacher, to help with a surprising business venture.

Dr. Linkletter pushes Sheldon to make friends with his fellow students, and Georgie gets a pager.

Sheldon, Dr. Linkletter and Meemaw team up on a science experiment. Mary is jealous that Pastor Jeff and Brenda are spending so much time together.

Sheldon accuses Amy of not following the bathroom schedule. Meanwhile, Howard and Bernadette's staycation is interrupted by hot tub interlopers.

Feeling his baby kick sends Howard on a baby-items buying binge with Raj, Sheldon and Amy host a brunch, and Penny is invited to a sci-fi convention.

Amy fibs about repairs being made to her apartment. Later, they present an episode of 'Fun with Flags' in Penny's apartment.

A successful gene experiment leaves Sheldon excited to procreate with Amy. Raj is reluctant to reveal what his new woman does for a living.

A coworker's MacArthur Genius fellowship award leaves Sheldon stone cold jealous. Howard finds a remote-control Stephen Hawking action figure.

A divide develops between Sheldon and Leonard when divvying up their shared belongings. Raj and Stuart battle to provide Bernadette the most help.

While Sheldon and Amy celebrate Amy's birthday, Howard and Bernadette welcome their new Baby Wolowitz.

Sheldon and Amy visit Leonard and Penny for the first time since the holidays and share details about their terrible trip to Texas.

Sean Combs rises to new heights, soon reaching billionaire status. However, behind his empire, people come forward with allegations of mistreatment.

Publicly, Sean Combs and Cassie Ventura become a power couple, but witnesses reveal allegations of abuse by Combs toward Cassie kept quiet for years.

Haunted by his time working for Diddy, a former assistant comes forward. Phil Pines claims he was forced to supply drugs and set up Wild King Nights.

In 1981, two men rape and shoot a young mother, forcing her fiance to watch it all. It will take two decades before justice prevails over the men.

Lookin' For Love In Lumpy Places. Gabriel has a huge growth on his clavicle but is terrified of surgery. Karen has dealt with painful, scaly feet for 22 years with no diagnosis.

Ruben is a personal trainer whose head growth has prevented him from seeing clients. Kaitlin has blue marks and scars due to long-term drug use.

Octavia has been bedbound for nearly a year. But, with her best friend as her worst enabler, can she choose between old habits and a new life.

Rachel struggles to find the perfect gown when the dress of her dreams is no longer available. Plus, bride Ellie falls in love with two fishtail styles.

Here come the quirky brides! Tensions rise when fashionista Annushka and her mum can't agree on a dress. Wacky bride Willow considers an understated style.

Amy wants a dress with sleeves but her entourage fall in love with a strapless gown. Plus, Ellie clashes with her mum over how much cleavage to show.

Mike dresses as Santa but feels more like the Grinch when he can't contain his frustrations over Molly's Christmas spending.

In an effort to boost their chances of getting pregnant, Molly encourages Mike to join her in giving up caffeine and eating healthier.

Mike risks losing his eyebrows when he starts construction on the basement for he and Molly, while Carl invites Samuel to move in with him.

Sheldon campaigns to become Dr. Linkletter's lab assistant. Georgie enlists the drama teacher, to help with a surprising business venture.

Dr. Linkletter pushes Sheldon to make friends with his fellow students, and Georgie gets a pager.

Sheldon, Dr. Linkletter and Meemaw team up on a science experiment. Mary is jealous that Pastor Jeff and Brenda are spending so much time together.

Sheldon accuses Amy of not following the bathroom schedule. Meanwhile, Howard and Bernadette's staycation is interrupted by hot tub interlopers.

Feeling his baby kick sends Howard on a baby-items buying binge with Raj, Sheldon and Amy host a brunch, and Penny is invited to a sci-fi convention.

Amy fibs about repairs being made to her apartment. Later, they present an episode of 'Fun with Flags' in Penny's apartment.

A successful gene experiment leaves Sheldon excited to procreate with Amy. Raj is reluctant to reveal what his new woman does for a living.

A coworker's MacArthur Genius fellowship award leaves Sheldon stone cold jealous. Howard finds a remote-control Stephen Hawking action figure.

A divide develops between Sheldon and Leonard when divvying up their shared belongings. Raj and Stuart battle to provide Bernadette the most help.

While Sheldon and Amy celebrate Amy's birthday, Howard and Bernadette welcome their new Baby Wolowitz.

Sheldon and Amy visit Leonard and Penny for the first time since the holidays and share details about their terrible trip to Texas.

Mike and Molly encourage Harry to take Victoria on a date for Valentine's Day, and everyone is shocked when she accepts.

Mike studies male fertility and visits a clinic to ensure that his 'swimmers' are up to the task of starting a family with Molly.

Molly enjoys some retail therapy and goes off on a shopping spree after Mike storms off over a disagreement and disappears at the mall.

The Geezer Bus And A New Model. Sheldon refuses to ride in a car after getting into an accident with Meemaw. Meemaw is forced to take the church shuttle.

When the IRS accuses Sheldon of making a mistake, he stops at nothing to prove them wrong. Meanwhile, Dale is forced to get a colonoscopy.

Sheldon faces consequences after installing a pirated computer game. Mary and Meemaw take Brenda out for Girls Night, and George watches Billy.

After a disagreement, Penny takes off for a spa weekend, and Sheldon plays peacemaker. Howard and Raj battle a noisy floor in the baby's room.

Sheldon tests an MIT invention, Leonard has trouble when Penny announces her brother's visit, and Raj seeks advice from old girlfriends.

Leonard and Howard engineer a distraction for Sheldon to keep him from hindering progress on the guidance-system project.

Amy is incensed when she learns Sheldon has shared intimate relationship information, and Raj's father stops sending financial support.

Raj finds himself in a cash crunch and turns to Sheldon to help him. Meanwhile, Penny considers crashing the guys' annual Comic-Con getaway.

Leonard and Penny offer Sheldon's old room to Raj after he moves out of his apartment.

Raj moves in with Leonard and Penny, and a period of adjustment begins, while usually self-centred Sheldon shows surprising interest in Amy's work.

Sheldon is pushing himself with too many collaborations. Bernadette's maternity leave is running out, and she must face going back to work.

Emma and Adam set up a seemingly perfect arrangement: no strings attached. But when a fling becomes a thing, can sex friends stay best friends.

Dr. Lee treats Reginald, who has a rare growth on the back of his head. Che'Re has a prominent bump on her face, and Juan has painful boils on his neck.

Margarita is a matriarch who has been hiding her armpit lump from her family. Bradley has a concerning growth that looks like raw meat on his leg.

Jeremy is a pastor with a hanging growth in an embarrassing location. Todd has a bump protruding from his forehead that is painful and humiliating.

Siblings Robin and Chris are both obese and already lost a sibling to obesity. Chris's son Garrett, already 600lbs at age 20, wants to lose weight.

The Desire For Something Different Show. Frankie's after something out of the ordinary but can she get her mum on board? At her final fitting, Jodie's not sure she'll like her dress.

Kayleigh envisions a sophisticated look for her wedding, but mum wants her to look like a princess. And Stephanie desires the ultimate elegant gown.

The Be True To Yourself Show. Former Miss Jamaica UK, Sanchia, wants a princess ballgown as fitted frocks remind her of her pageant days. Will she compromise to stay true to herself.

Lindi knows what she wants, but her persistent sister-in-law is determined to sway her decision! And, Ginny-May and her mum have a fashion face-off.

Mike and Molly encourage Harry to take Victoria on a date for Valentine's Day, and everyone is shocked when she accepts.

Mike studies male fertility and visits a clinic to ensure that his 'swimmers' are up to the task of starting a family with Molly.

Molly enjoys some retail therapy and goes off on a shopping spree after Mike storms off over a disagreement and disappears at the mall.

The Geezer Bus And A New Model. Sheldon refuses to ride in a car after getting into an accident with Meemaw. Meemaw is forced to take the church shuttle.

When the IRS accuses Sheldon of making a mistake, he stops at nothing to prove them wrong. Meanwhile, Dale is forced to get a colonoscopy.

Sheldon faces consequences after installing a pirated computer game. Mary and Meemaw take Brenda out for Girls Night, and George watches Billy.

After a disagreement, Penny takes off for a spa weekend, and Sheldon plays peacemaker. Howard and Raj battle a noisy floor in the baby's room.

Sheldon tests an MIT invention, Leonard has trouble when Penny announces her brother's visit, and Raj seeks advice from old girlfriends.

Leonard and Howard engineer a distraction for Sheldon to keep him from hindering progress on the guidance-system project.

Amy is incensed when she learns Sheldon has shared intimate relationship information, and Raj's father stops sending financial support.

Raj finds himself in a cash crunch and turns to Sheldon to help him. Meanwhile, Penny considers crashing the guys' annual Comic-Con getaway.

Leonard and Penny offer Sheldon's old room to Raj after he moves out of his apartment.

Raj moves in with Leonard and Penny, and a period of adjustment begins, while usually self-centred Sheldon shows surprising interest in Amy's work.

Sheldon is pushing himself with too many collaborations. Bernadette's maternity leave is running out, and she must face going back to work.

Carl and Samuel host a party in hopes of attracting some ladies. Meanwhile, Molly reveals secrets from her previous St. Patrick's Day excursions.

Molly joins her sister on a Spring Break road trip to party with Victoria's friends from junior college, while Mike asks his boss for some overtime.

Molly and Peggy try to play nice for Mike's birthday. Meanwhile, Samuel and Carl compete for the same woman.

Sheldon is at odds with Paige once again when she considers enrolling at East Texas Tech. Mary seeks the advice of June when looking for a change.

The Coopers discuss the possibilities of black holes and alternate universes when Dr. Sturgis comes over for dinner.

Missy's first heartbreak triggers a series of events that lead the Cooper family to the brink.

Leaving the baby in daycare proves to be tough for Bernadette, and geologist Bert digs up a girlfriend, but some colleagues think she's a gold digger.

Leonard isn't thrilled when Penny considers taking a new job offered by her ex-boyfriend, Zack.

Leonard, Sheldon and Wolowitz celebrate the completion of their top-secret military project, until an unpleasant surprise leaves their heads spinning.

Sheldon's former admirer, Dr. Ramona Nowitzki, turns up while Amy is visiting Princeton, and the gang is extremely concerned.

What did she say? Amy answers Sheldon's marriage proposal. Meanwhile, Howard and Bernadette struggle with some unexpected news.

Leonard's job is at stake when he gives an embarrassing radio interview which angers the university and the entire physics community.

Amy tries to convince Sheldon that he has a more laid-back side, meanwhile, Raj and Stuart compete to win the heart of Bernadette's new co-worker.

Wolowitz and Sheldon bond over their relationships with their disappointing fathers. And Leonard's mum finds a new best friend in Penny.

Jason isolates due to a giant neck growth. Marisa dreads spider veins after surgery and Kobe hums to stay calm as a huge bump near his eye is removed.

Bryan's head bumps puzzle doctors. Chalamar hates her chest lump and Dr. Lee and Dr. Lyndsey help Devi regain her bikini body and confidence.

Drag queen Tameru is covered in tiny clusters of cysts on his chest, arms and neck. He discovered his bumps over a decade ago and still doesn't know what they are.