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An obscure print found at a crime scene.

A diner in a small town, an endocrinologist and a forensic botanist help destroy a prime suspect's alibi.

Neighbors do not hear the gunshots when a union official is killed in his home.

A man tells police he shot an intruder who murdered his wife; forensic evidence leads police to re-examine the man's motives.

A police officer claims his estranged wife's shooting death was a suicide, but investigators think it was a murder.

When firefighters find a family dead inside their home, it appears to be a murder-suicide; clues at the scene lead investigators to believe otherwise.

A couple's murder leads investigators into the world of white supremacists and a string of hate crimes.

A rare gun and a victim's beloved dog help investigators trying to solve a multi-year-long murder case where most of the witnesses were admitted drug users.

A search in Virginia's DNA databank reveals the identity of a news producer's murderer.

A homicide detective claims his wife accidentally shot herself in the head, but the evidence indicates otherwise.

Officials probe the death of a woman investigating the possible side effects of the drug she was prescribed for bipolar disorder.

A chip of stainless steel brings a killer to justice 20 years after a woman's body is found in a ravine.

An 11-year-old girl is sexually assaulted and shot twice at close range.

A woman is killed weeks before testifying against the man who sexually assaulted her.

New York police hunt the Zodiac killer after a series of deadly attacks.

When a healthy young man dies mysteriously in his sleep, toxicology tests reveal that it may have been foul play. Could a "suicide note" hold the key to solving the case?

A child's memory, a diary and a forensic psychologist help investigators solve a young woman's murder.

Investigators weigh several theories while probing the death of a retired police officer, including a botched robbery and suicide.

The bodies of two young women are found in the ashes of an apartment fire.

Two different men report the murder of a single mother and when the case's other anomalies stall the police, a candy wrapper and seeds help expose the killer.

After a Connecticut man's body is found in a burning rental car on a Mexican highway, an insurance company suspects a scam.

When a pipe bomb rips through a rural home, killing a young man and seriously injuring his mother, detectives hope that the remnants of a mailing label will lead them to a killer.

Stories from across the world and refreshing conversations with Audie Cornish.

Joining the table for a provocative discussion of the week's stories.

Detectives use a forged signature to find a woman's abductor.

A woman is killed two days before she was scheduled to testify against a man accused of assaulting her and the prime suspect has an alibi.

A bite mark is all the evidence needed to convict a suspect who was robbing tourists in Florida.

Technology able to analyze human bite-marks yields information on a woman's death.

A death in Pennsylvania is strikingly similar to one in North Carolina.

When a nurse starts experiencing a variety of flu-like symptoms, she discovers that she is HIV-positive; she learns that her infection was not accidental.

Time of death becomes pivotal when a pregnant woman is found murdered in her air-conditioned bedroom.

An obscure print found at a crime scene.

A diner in a small town, an endocrinologist and a forensic botanist help destroy a prime suspect's alibi.

Neighbors do not hear the gunshots when a union official is killed in his home.

A man tells police he shot an intruder who murdered his wife; forensic evidence leads police to re-examine the man's motives.

A police officer claims his estranged wife's shooting death was a suicide, but investigators think it was a murder.

When firefighters find a family dead inside their home, it appears to be a murder-suicide; clues at the scene lead investigators to believe otherwise.

A couple's murder leads investigators into the world of white supremacists and a string of hate crimes.

A rare gun and a victim's beloved dog help investigators trying to solve a multi-year-long murder case where most of the witnesses were admitted drug users.

A search in Virginia's DNA databank reveals the identity of a news producer's murderer.

A quiet residential community, shattered by the murder of a neighbor. See how modern techniques helped investigators catch the culprit in less than 12 hours.

A man is found dead in his Michigan auto-salvage shop.

A man is murdered in a drive-by shooting. When a mobile phone trace incriminates a killer, it's up to a forensic geologist to find evidence that he was at the scene.

When a teenage girl is found dead, her boyfriend confesses to her murder. However, in a strange twist, so does another man; police must determine which is the killer.

A high school gym teacher gives his friend a ride home but never returns; his wife and friend receive letters saying he started a new life, but they suspect foul play despite no body being discovered.

A 16-year-old girl is killed in her own home by her mother and father. Her parents said they acted in self-defense, but the forensic evidence indicates otherwise.

Investigators determine if a computer crash which almost ruined a manufacturing company was accidental or deliberate sabotage.

Car with three Secret Service agents collides with local deputy's car; investigation launched into who was responsible for the deadly car accident finds two very different conclusions.

The derailment of the Sunset Limited was the deadliest train crash in U.S. history killing 47 passengers and crew with several more injured.

Arson investigators attempt to determine the cause of the 1987 fire at the Kings Cross Underground Station in London.

A discarded sleeping bag, containing bloody sneakers and a purse, leads police to the body of a young woman; a mark found on the victim's body enables police to track the killer.

A woman's apparent accidental death begins to look fishy after police uncover a letter written by the victim days before her untimely death.

An Alaskan trooper finds a woman's body beside a frozen road, but evidence is scant even after a suspected murder weapon is found.

Police link a clump of hair discovered in an isolated area with a woman who disappeared 20 years ago.

A news anchor is shot to death outside her home in an apparent crime of passion by a fan; a police dog tracks the scent of the killer back to the crime scene.

A fire, caused by an unattended cigarette, kills the estranged wife of a police officer; forensic scientists discover that the cause is far more complicated.

A trio of men, responsible for several bank robberies, leaves no evidence behind; forensic scientists help catch them by looking at the criminals' posture and clothing.

When a woman's bone marrow test reveals arsenic poisoning, investigators try to determine if it is due to groundwater contamination or something more sinister.

A missing bank president's body is found floating in a lake; the duct tape used in binding him to a chair helps solve the crime.

A husband was shot and killed, forensic psychiatry helped the wife to remember the details for what happened.

The body of a 16-year-old girl is discovered nine months after her disappearance; forensic scientists find clues that paint a virtual portrait of her killer.

A young woman falls to her death in what appears to be a tragic accident; a forensic exam of photos taken at the scene tells a different story.

Haunted by her mother's long-ago disappearance, a woman undertakes an investigation of her own and stumbles upon a dark family secret.

The robbery and brutal murder of an elderly couple goes unsolved for 10 years; a forensic scientist makes history when he solves the crime.

A man is charged with the murder of a wrestling champion; six years later, a forensic animator testifies on his behalf.

A 19-year-old girl is found dead in her car in what appears to be a suicide; police discover that the victim was involved in a love quadrangle, giving several people motive to kill.

Fifteen years after a man disappears, using a metal detector, police find evidence which proves what had happened.

The body of a young California co-ed under an isolated interstate ramp sets off an investigation; San Diego police have no idea who would want her dead, but they discover a tiny, unique fiber on the victim's clothing.

Stories from across the world and refreshing conversations with Audie Cornish.

Stories from across the world and refreshing conversations with Audie Cornish.

Melanie Zanona; Catherine Lucey; Isaac Arnsdorf.

A homicide detective claims his wife accidentally shot herself in the head, but the evidence indicates otherwise.

Officials probe the death of a woman investigating the possible side effects of the drug she was prescribed for bipolar disorder.

A chip of stainless steel brings a killer to justice 20 years after a woman's body is found in a ravine.

An 11-year-old girl is sexually assaulted and shot twice at close range.

A woman is killed weeks before testifying against the man who sexually assaulted her.

New York police hunt the Zodiac killer after a series of deadly attacks.

When a healthy young man dies mysteriously in his sleep, toxicology tests reveal that it may have been foul play. Could a "suicide note" hold the key to solving the case?

A child's memory, a diary and a forensic psychologist help investigators solve a young woman's murder.

Investigators weigh several theories while probing the death of a retired police officer, including a botched robbery and suicide.

The bodies of two young women are found in the ashes of an apartment fire.

Two different men report the murder of a single mother and when the case's other anomalies stall the police, a candy wrapper and seeds help expose the killer.

After a Connecticut man's body is found in a burning rental car on a Mexican highway, an insurance company suspects a scam.

When a pipe bomb rips through a rural home, killing a young man and seriously injuring his mother, detectives hope that the remnants of a mailing label will lead them to a killer.

A quiet residential community, shattered by the murder of a neighbor. See how modern techniques helped investigators catch the culprit in less than 12 hours.

Police become suspicious of a man who reported his wife missing 15 years after doing the same thing with his first wife.

While investigating the case of a Colorado hunter shot three times and killed, police suspect two murder weapons, and two killers, but forensic evidence points them closer to home.

A serial arsonist burns thousands of California homes and businesses.

A small community in upstate New York is devastated when a car accident claims the life of a well-respected nurse.

A woman disappears without a trace, and police learn two other women vanished under similar circumstances.

Hikers near Anchorage, Alaska discover a body wrapped in sheets edged in orange stitching; they discover threads of evidence clinging to the sheet.

The son of a murder victim contacts the police when a flight attendant is brutally murdered in a remarkably similar way.

A two-man shrimp boat sinks when a fast-moving, violent storm struck the Louisiana coast; a deckhand is considered a hero for trying to save the drowned captain, until his body is found.

A real estate tycoon must have had a premonition about foul play, as he wrote it in his will.

The cold-blooded murder of an American tourist in a Mexican resort causes law enforcement to focus on both sides of the border.

When a prominent banker's wife is kidnapped, the trail leads police on a wild goose chase; they track down disgruntled bank customers and examine computer fonts.

A man has no recollection of events after stabbing his wife and holding her head underwater in a swimming pool.

A fire investigator determines if a kerosene heater is the cause of a fire that killed one person or if it was murder.

California police in 1957 search for a murderer, but the case goes cold; 50 years after a crime is committed, advances in computer technology determine the killer.

Investigators piece together tiny clues at the scene of a hit-and-run accident; their findings help to track down the offending driver.

Investigators determine what caused a house fire that killed an elderly couple and whether the victims' son is responsible.

Detectives are suspicious after a woman is killed in a hunting accident, but it takes more than twenty years before a trace evidence analyst is able to match fibers on a soiled blanket to the killer.

When hunters find a skull in a Texas canyon, police find bits of clothing, a woman's shoe, some small bones and a strand of hair; once they discover her identity, it was time to find the killer.

A wife is missing in Key West; investigators wonder if they should be searching for a missing person or a killer.

Suicide notes and a pistol in hand lead police to suspect that a mother of two young children appeared to have killed herself, but when investigators learned of a house fire she was in three years earlier, they reinvestigated.

The violent death of an Air Force officer's wife outside a Philippines air base is examined, amid accusations of a love triangle involving the murdered woman's husband; investigators use groundbreaking computer forensics to make their case.

Pieces of plastic the size of sand hold clues to a bombing.

At first glance it appears a young woman suffocated, but further investigation shows the scene was staged.

A killer is careless when a home is destroyed by fire and a young boy is missing.

A patrol officer is shocked by the amount of blood at a traffic accident and is shocked by the coroner's ruling until an anonymous phone call re-ignites the case.

An irrigation canal murder remains unsolved until a similar murder occurs.

The light of day and DNA picture painted by molecular biologist reveals new clues about a nighttime traffic accident.

On Valentine's Day, an obstetrician finds his wife dead and calls 911; police discover inconsistencies between the blood spatter evidence and his version of events.

A young woman goes missing without leaving many clues, but the advanced technology on offer makes it possible for cat hairs and insects to help build an image of the abductor.

Blood spatter analysis and an investigation lead police to the truth when a pregnant woman is found dead in her home.

The anchors share the latest stories about significant events that take place across the world and interview prominent figures.

The anchors share the latest stories about significant events that take place across the world and interview prominent figures.

The anchors share the latest stories about significant events that take place across the world and interview prominent figures.

A man is found dead in his Michigan auto-salvage shop.

A man is murdered in a drive-by shooting. When a mobile phone trace incriminates a killer, it's up to a forensic geologist to find evidence that he was at the scene.

When a teenage girl is found dead, her boyfriend confesses to her murder. However, in a strange twist, so does another man; police must determine which is the killer.

A high school gym teacher gives his friend a ride home but never returns; his wife and friend receive letters saying he started a new life, but they suspect foul play despite no body being discovered.

CNN Chief Legal Analyst and anchor Laura Coates leads comprehensive live coverage and expert legal analysis of the trial of Duane Davis -- accused of orchestrating the infamous, long unsolved-murder of hip-hop icon Tupac Shakur in 1996.

CNN Chief Legal Analyst and anchor Laura Coates leads comprehensive live coverage and expert legal analysis of the trial of Duane Davis -- accused of orchestrating the infamous, long unsolved-murder of hip-hop icon Tupac Shakur in 1996.

CNN Chief Legal Analyst and anchor Laura Coates leads comprehensive live coverage and expert legal analysis of the trial of Duane Davis -- accused of orchestrating the infamous, long unsolved-murder of hip-hop icon Tupac Shakur in 1996.

CNN Chief Legal Analyst and anchor Laura Coates leads comprehensive live coverage and expert legal analysis of the trial of Duane Davis -- accused of orchestrating the infamous, long unsolved-murder of hip-hop icon Tupac Shakur in 1996.

CNN Chief Legal Analyst and anchor Laura Coates leads comprehensive live coverage and expert legal analysis of the trial of Duane Davis -- accused of orchestrating the infamous, long unsolved-murder of hip-hop icon Tupac Shakur in 1996.

CNN Chief Legal Analyst and anchor Laura Coates leads comprehensive live coverage and expert legal analysis of the trial of Duane Davis -- accused of orchestrating the infamous, long unsolved-murder of hip-hop icon Tupac Shakur in 1996.

CNN Chief Legal Analyst and anchor Laura Coates leads comprehensive live coverage and expert legal analysis of the trial of Duane Davis -- accused of orchestrating the infamous, long unsolved-murder of hip-hop icon Tupac Shakur in 1996.

Police blame a botched robbery when an eccentric elderly millionaire is found dead, but the motive could be wrong.

Woman disappears from grocery store parking lot in Boulder, Colo.; investigators find extraordinary clues in a pair of bloody gloves, unique tire tracks, and ordinary grass and pine needles.

A car carrying three men pulls up alongside another on an Alaskan highway and fires shots, leaving a passenger dead; one of the passengers in the killer's car agrees to testify against his friends; the resulting trials don't end the carnage.

Police suspect a gay college student's slaying is a hate crime until forensic evidence points the case in another direction.

In a wealthy area of Philadelphia, police are called to the scene of what seems like a regular accidental drowning; the investigation begins to focus on one person who has many reasons to want the victim dead.

Two women are murdered in the same town and police fear a serial killer is on the loose, further investigation finds that they were both close to the same man.

A young woman is found dead on a golf course in the Bahamas; the grass on that course is so distinctive that it had evidentiary value; the evidence leads police to two suspects; each blamed the other, and they have to find out who the killer is.

A teenager goes missing after an evening of horseback riding; her body is found a month later, three miles from her home; the killer unknowingly leaves a trace of evidence behind, tiny but unmistakable clues that pointed to him and him alone.

When a popular disc jockey is found murdered in a community garden, police swing into action; a sniffer dog and a blood spatter expert led police to the killer, and he'd been much closer than they realized.

Investigators unravel a twisted tale of lust, greed and deception after a woman claims her husband was gunned down by intruders.

Three seemingly unrelated deaths proved to be serial murders; the killer had been careful, he used poison which had no taste or odour; fortunately for investigators, it also has a unique chemical signature.

A man is murdered in his sleep but no fingerprints are anywhere to be found; a shoe impression outside could lead to the killer.

With very little else to go on, investigators find that a show impression puts them on the right track to finding a killer in Lansing, Mich.

The owner of a restaurant is killed; investigators uncover tales of debt and deceit, but the case remains open, until one detective gets inspired by an earlier episode of "Forensic Files," and looks for clues in an empty holster.

A serial arsonist was on the loose in Washington, DC. Each of the fires was started with the same type of incendiary device. The perpetrator was very careful, and seemed to leave no evidence behind... but there were clues in the ashes, and it was up to forensic scientists to find them.

A man becomes the prime suspect in his wife's death after forensic science raises questions about her apparent suicide.

Investigators on both sides of the Atlantic seek links between three homicides that look like professional executions.

Who put a bomb in the home of a 29-year-old woman and killed her?

A killer tried to destroy everything which could link them to the crime; but in doing so, they inadvertently created new forensic evidence, evidence which came to light using a technique never before used in a criminal investigation.

After a tycoon's wife is found dead in her SUV submerged in a half-frozen creek, police begin to suspect it wasn't an accident.

A Russian immigrant is found dead and a strange phone call to his office is the only lead investigators have.

Physical evidence initially condemns a prime suspect to a double homicide, but DNA from a discarded spoon points to another.

A mother is determined to discover what happened when her daughter is injured in a hit-and-run accident.

Forensic science and deductive reasoning determine what happened to a mother and daughter while they were on a shopping spree.

The anchors share the latest stories about significant events that take place across the world and interview prominent figures.

The anchors share the latest stories about significant events that take place across the world and interview prominent figures.

The anchors share the latest stories about significant events that take place across the world and interview prominent figures.

Police link a clump of hair discovered in an isolated area with a woman who disappeared 20 years ago.

A news anchor is shot to death outside her home in an apparent crime of passion by a fan; a police dog tracks the scent of the killer back to the crime scene.

A fire, caused by an unattended cigarette, kills the estranged wife of a police officer; forensic scientists discover that the cause is far more complicated.

CNN Chief Legal Analyst and anchor Laura Coates leads comprehensive live coverage and expert legal analysis of the trial of Duane Davis -- accused of orchestrating the infamous, long-unsolved murder of hip-hop icon Tupac Shakur in 1996.

CNN Chief Legal Analyst and anchor Laura Coates leads comprehensive live coverage and expert legal analysis of the trial of Duane Davis -- accused of orchestrating the infamous, long-unsolved murder of hip-hop icon Tupac Shakur in 1996.

CNN Chief Legal Analyst and anchor Laura Coates leads comprehensive live coverage and expert legal analysis of the trial of Duane Davis -- accused of orchestrating the infamous, long-unsolved murder of hip-hop icon Tupac Shakur in 1996.

CNN Chief Legal Analyst and anchor Laura Coates leads comprehensive live coverage and expert legal analysis of the trial of Duane Davis -- accused of orchestrating the infamous, long-unsolved murder of hip-hop icon Tupac Shakur in 1996.

CNN Chief Legal Analyst and anchor Laura Coates leads comprehensive live coverage and expert legal analysis of the trial of Duane Davis -- accused of orchestrating the infamous, long-unsolved murder of hip-hop icon Tupac Shakur in 1996.

CNN Chief Legal Analyst and anchor Laura Coates leads comprehensive live coverage and expert legal analysis of the trial of Duane Davis -- accused of orchestrating the infamous, long-unsolved murder of hip-hop icon Tupac Shakur in 1996.

CNN Chief Legal Analyst and anchor Laura Coates leads comprehensive live coverage and expert legal analysis of the trial of Duane Davis -- accused of orchestrating the infamous, long-unsolved murder of hip-hop icon Tupac Shakur in 1996.

CNN Chief Legal Analyst and anchor Laura Coates leads comprehensive live coverage and expert legal analysis of the trial of Duane Davis -- accused of orchestrating the infamous, long-unsolved murder of hip-hop icon Tupac Shakur in 1996.

Investigators search the world of high rollers and offshore betting to solve the first triple homicide in Verona, Wisc.

Police search every apartment building in town when the body of a young girl found on an isolated farm holds a set of keys but no ID.

A man denies killing a pedestrian in hit-and-run, claiming he sold the car in question; authorities track down the car to find critical evidence.

Three years later, a second autopsy determines who's right when a medical examiner and detectives disagree on the cause of death.

Hit-and-run boating accident that kills a popular young man causes investigators to search for one boat out of thousands.

A woman is found dead on her bedroom floor, the only clue is a bloodstained sheet; breakthrough forensics enable police to identify the killer.

A young man is killed in a mysterious car crash, but the evidence at the scene lead investigators to believe it is not an accident; forensic science reveals what really happens, and the truth devastates three families.

A woman is found dead, police use blood evidence and computer forensics to convince a jury that the murderer is guilty.

When an elderly woman dies in an apparent robbery-homicide, evidence suggests the suspect broke out of the house rather than breaking in.

Wealthy man is shot dead while his wife is forced to open their hidden safe, but they couldn't be identified because they were wearing ski masks.

The bomb was constructed to cause as much damage as possible, and it did, killing the victim with deadly force and flame; a painstaking search yielded tiny clues, which identified the killer as surely as if he'd signed them.

A twelve-year-old girl claims that she was abducted and sexually assaulted; her story seems unbelievable until police discover fibers on her clothing.

A man calls for help when his wife has a fatal fall down the stairs; numerous amount of bloodstains make police suspicious.

A decade old case reopens, and a few seconds of a 911 call enable investigators to determine who is responsible for a murder.

A flawed envelope is an unlikely clue to identifying a killer who laced a water cooler with cyanide and caused the death of a woman.

A mussel diver and his fiancée are found dead in their burnt home; a tiny clue points to arson and murder.

For ten years, the disappearance of a college co-ed remained a mystery; new scientific testing cast a different light on a man who had been a suspect all along.

Tipster is found dead after revealing that a woman's death 16 years ago was murder.

The murder of 53-year-old Paul Gruber is examined, and the evidence points to Darryl Robin Kuehl, who was later convicted of the crime.

A man states that a robber shot and killed his wife while they were on the beach, but a song he downloaded makes investigators suspicious.

Detectives discover new clues left by a stalker's letter to his victim.

The body of an insurance assessor is found in a river in Tampa, Fla.; a unique murder weapon and blatant clues lead the police straight to her careless killer.

Exploring how an American hit single from 1966 -- "The Cheater" by Bob Kuban and the In-Men -- foreshadowed the demise of the group's lead singer, Walter Scott.

Eight years after a man confessed to the murder of a young woman, another man claims that he committed the crime, and investigators must use forensic evidence to determine the true killer.

The anchors share the latest stories about significant events that take place across the world and interview prominent figures.

The anchors share the latest stories about significant events that take place across the world and interview prominent figures.

The anchors share the latest stories about significant events that take place across the world and interview prominent figures.

A 19-year-old girl is found dead in her car in what appears to be a suicide; police discover that the victim was involved in a love quadrangle, giving several people motive to kill.

Fifteen years after a man disappears, using a metal detector, police find evidence which proves what had happened.

The body of a young California co-ed under an isolated interstate ramp sets off an investigation; San Diego police have no idea who would want her dead, but they discover a tiny, unique fiber on the victim's clothing.

Police become suspicious of a man who reported his wife missing 15 years after doing the same thing with his first wife.

While investigating the case of a Colorado hunter shot three times and killed, police suspect two murder weapons, and two killers, but forensic evidence points them closer to home.

A serial arsonist burns thousands of California homes and businesses.

A small community in upstate New York is devastated when a car accident claims the life of a well-respected nurse.

A woman disappears without a trace, and police learn two other women vanished under similar circumstances.

Hikers near Anchorage, Alaska discover a body wrapped in sheets edged in orange stitching; they discover threads of evidence clinging to the sheet.

The son of a murder victim contacts the police when a flight attendant is brutally murdered in a remarkably similar way.

A two-man shrimp boat sinks when a fast-moving, violent storm struck the Louisiana coast; a deckhand is considered a hero for trying to save the drowned captain, until his body is found.

CNN Chief Legal Analyst and anchor Laura Coates leads comprehensive live coverage and expert legal analysis of the trial of Duane Davis -- accused of orchestrating the infamous, long-unsolved murder of hip-hop icon Tupac Shakur in 1996.

CNN Chief Legal Analyst and anchor Laura Coates leads comprehensive live coverage and expert legal analysis of the trial of Duane Davis -- accused of orchestrating the infamous, long-unsolved murder of hip-hop icon Tupac Shakur in 1996.

CNN Chief Legal Analyst and anchor Laura Coates leads comprehensive live coverage and expert legal analysis of the trial of Duane Davis -- accused of orchestrating the infamous, long-unsolved murder of hip-hop icon Tupac Shakur in 1996.

CNN Chief Legal Analyst and anchor Laura Coates leads comprehensive live coverage and expert legal analysis of the trial of Duane Davis -- accused of orchestrating the infamous, long-unsolved murder of hip-hop icon Tupac Shakur in 1996.

A wax bullet, white blanket and olive colored carpeting tell a lot about the murder of a young woman found in a ravine.

When a house burns to the ground and a woman's charred remains are found, investigators must determine whether it was an accident or arson.

An ammunition box and fluorescent fibers reveal the betrayal that led to the murder of a millionaire's family.

The 1960 kidnapping and murder of brewery heir Adolph Coors III leads to one of the most intense manhunts in U.S. history.

A used tissue, 12 years after the murder of a young Missouri woman, may be what cracks the case with a suspect list a mile long.

When murder strikes a young girl, police quickly make an arrest, but cutting-edge technology from NASA proves they have the wrong suspect behind bars.

A man is found strangled and burned in his San Antonio apartment and the killer thinks he has destroyed all the evidence.

When two men appear to die of heart disease six years apart, police notice they have one thing in common, they were each married to the same woman.

Casino security cameras offer the final images of a woman, just before she vanishes without a trace; can these grainy images lead police to her killer?

A squashed tomato and a pinpoint reflection of light in a photo help catch a killer.

An ATM transaction allows Texas detectives to pinpoint a suspect in the slaying of a teacher, but a shoelace stolen from the victim's home proves to be the tie that binds her killer to the crime.

Ten years after the murder of a rock singer, forensic scientists use evidence collected to finally bring her killer to justice.

After a Michigan State University grad student disappears and is presumed dead, a professor of geological sciences helps police get the dirt on her killer.

When a man's wife kills herself 14 years after his college sweetheart commits suicide, police start to get suspicious.

A woman gets shot in her driveway; she may have been the victim of a co-worker half her age that she had recently rejected.

A pair of tennis shoes are found near a victim who had been stabbed on the beach, less than ten yards from her hotel.

Three fingerprints on a window screen are enough for a print examiner to uncover the work of a serial killer.

With a long list of suspects, forensic experts agree on one thing in this brutal murder: the killer knew his victim.

The only lead to finding a serial killer on the loose is a bloody fingerprint on the body of a victim.

Tests reveal the race, eye color and hair color of the person responsible for killing two young women on Halloween night.

A convicted arsonist claims his innocence and with no lawyer, no money and only a fifth-grade education, sets out to prove it.

A canine behaviorist uses the family dogs, who are the only witnesses, to find the murderer of their owner.

Although a group of teenage thugs are suspected of attacking two boys on a fishing trip, there is no solid evidence until a murky fishing hole provides some answers.

When young prostitute's body turns up in an Ohio waterway, authorities have one tiny clue which could point to her killer, but face huge challenges due to her policemen clients and DNA evidence being washed away.

The anchors share the latest stories about significant events that take place across the world and interview prominent figures.

The anchors share the latest stories about significant events that take place across the world and interview prominent figures.

The anchors share the latest stories about significant events that take place across the world and interview prominent figures.

The cold-blooded murder of an American tourist in a Mexican resort causes law enforcement to focus on both sides of the border.

When a prominent banker's wife is kidnapped, the trail leads police on a wild goose chase; they track down disgruntled bank customers and examine computer fonts.

A man has no recollection of events after stabbing his wife and holding her head underwater in a swimming pool.

A fire investigator determines if a kerosene heater is the cause of a fire that killed one person or if it was murder.

California police in 1957 search for a murderer, but the case goes cold; 50 years after a crime is committed, advances in computer technology determine the killer.

Investigators piece together tiny clues at the scene of a hit-and-run accident; their findings help to track down the offending driver.

Investigators determine what caused a house fire that killed an elderly couple and whether the victims' son is responsible.

Detectives are suspicious after a woman is killed in a hunting accident, but it takes more than twenty years before a trace evidence analyst is able to match fibers on a soiled blanket to the killer.

When hunters find a skull in a Texas canyon, police find bits of clothing, a woman's shoe, some small bones and a strand of hair; once they discover her identity, it was time to find the killer.

A wife is missing in Key West; investigators wonder if they should be searching for a missing person or a killer.

Suicide notes and a pistol in hand lead police to suspect that a mother of two young children appeared to have killed herself, but when investigators learned of a house fire she was in three years earlier, they reinvestigated.

CNN Chief Legal Analyst and anchor Laura Coates leads comprehensive live coverage and expert legal analysis of the trial of Duane Davis -- accused of orchestrating the infamous, long-unsolved murder of hip-hop icon Tupac Shakur in 1996.

CNN Chief Legal Analyst and anchor Laura Coates leads comprehensive live coverage and expert legal analysis of the trial of Duane Davis -- accused of orchestrating the infamous, long-unsolved murder of hip-hop icon Tupac Shakur in 1996.

CNN Chief Legal Analyst and anchor Laura Coates leads comprehensive live coverage and expert legal analysis of the trial of Duane Davis -- accused of orchestrating the infamous, long-unsolved murder of hip-hop icon Tupac Shakur in 1996.

CNN Chief Legal Analyst and anchor Laura Coates leads comprehensive live coverage and expert legal analysis of the trial of Duane Davis -- accused of orchestrating the infamous, long-unsolved murder of hip-hop icon Tupac Shakur in 1996.

After 10 years, a witness decides to do the right thing about the rape and murder of a young hairdresser.

Police investigate the possibility of a hate crime when two women go missing and are later found murdered.

When a human skeleton is found on marshland and determined to be at least 18 months old, a computer consultant gives her a face and name.

A killer places all the incriminating evidence to the murder in a plastic bag, hoping it will float down the river.

A woman's body is found inside a burned mobile home and the autopsy reveals she was beaten, making this a murder.

Security guard who disappeared from his post was found a year later in a remote camp site; a decade later, a phone call and a paint smear on his boot helped scientists determine what happened during his final moments.

When three students are brutally murdered close to campus, investigators must determine what the women had in common before their serial killer strikes again.

A bag full of evidence recovered from an iced-over river helps to reveal the murderer of a businesswoman in her own shop.

Eyewitness to real estate agent's murder is put under forensic hypnosis in an attempt to help him recall the killer's face.

Police launch a search for a killer after a teenager returns home to find his father's body in a pool of blood.

Pathologist examining the death of a politician who was running for re-election finds tiny puncture wounds at the autopsy.

A Naval officer who threatened to go public with tales of on-the-job sexual harassment and assault is brutally murdered, but when investigators find the allegations could be part of an elaborate scheme for money, they turn to forensic science.