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Dara Ó Briain extracts humour from current events with guests Rhys James, Neil Delamere, Milton Jones, Zoe Lyons, Sara Pascoe and Ahir Shah.

When Dr. Sturgis bonds with Paige, another 10-year-old genius, Sheldon gets jealous. Meanwhile, Mary invites Paige's family over for a play date.

Jack fainted during a previous attempt to remove his throat bump. Can Dr. Lee help this time? Plus, Dr. Tomassian reconstructs Victoria's earlobes.

Pimple Popper. Angelina's huge chest lump affects her love life and Delano has a football-sized mass on his back. Plus, Carla hopes to get painful cysts removed from her scalp.

At 670 pounds, Ashley is desperate to save her life and her marriage to husband David. Can weight-loss surgery give her the chance for a family of her own.

New mum Laura has seen her dream dress online, but will she love its lacey A-line style in real life? Lutifah has two wedding gowns, but fears they won't fit.

Kristin wants the advice of her friends to help her find the perfect gown. Problems arise when she thinks she's found the one, but her friends don't agree.

Nikki looks for a dress that will wow at her big fat Greek wedding. Stephanie is keen to show off her newly slender figure and hopes to find a fitted frock.

The Hecks spend New Year's Day at the Orson Escape Room. Mike is stunned when Frankie reveals that she had a romantic dream involving Frank Sinatra.

Frankie is elated when she wins a month of free maid service. Axl, Hutch and Kenny attempt to move in with Sue and Lexie in their college housing.

Brad agrees to coach Sue's no-cut acapella group. Brick asks for Frankie and Mike's advice when girlfriend Cindy tells him that he reads too much.

When Meemaw is pursued by two gentlemen callers, Sheldon interferes, forcing her to set some ground rules.

Sheldon dismantles the refrigerator to stop an annoying hum and then must get a paper route to pay for the repairs.

When Dr. Sturgis bonds with Paige, another 10-year-old genius, Sheldon gets jealous. Meanwhile, Mary invites Paige's family over for a play date.

Amy doesn't have time to work on a project, so Sheldon goes to great lengths to ensure she can work with him, even if it means sabotaging her career.

When Howard dresses up as Sheldon for Halloween, Sheldon seeks retaliation. Leonard is shocked that Penny doesn't remember their first kiss.

Leonard is caught in a tough spot when he's responsible for distributing extra grant money. Bernadette turns the backyard playhouse into a hideaway.

Sheldon tries to bond with Amy's father, but Howard lures Mr. Fowler away with magic tricks. Raj and Anu try to get physical for the first time.

Sheldon and Amy are devastated learning that Super Asymmetry has been discovered and disproven. Bernadette asks Denise to help her win a videogame.

A VHS tape inspires Sheldon to not give up on his and Amy's theory. Bernadette turns into a pageant mom over Howard's Magic Castle audition.

Penny and Leonard organise a paintball game that results in mayhem. Raj catches Anu with her ex, and Stuart doesn't want to move in with Denise.

Penny's ex, Zack, and his wife want a baby, but when Zack is infertile, they ask Leonard to help. Raj attempts to mend things with his ex-fiancée.

Frankie is sad when informed that her days of having kids are over. Sue and Axl are shocked when her roommate and Sean Donahue start flirting.

Frankie and Mike frantically attempt to shut off the water when the pipes burst. The Hecks call a meeting to deal with their bickering.

Mike's dislike of dentistry leads to escalating falsehoods to avoid having his toothache fixed. Brick attempts to write a Scottish-themed rap musical.

When Mary's faith is shaken by a tragedy in the community, Sheldon becomes an unlikely ally.

When George Sr. asks Sheldon to keep a secret from Mary, the stress of not being honest drives Sheldon to hide out at Tam's for his first sleepover.

Dr. Sturgis recommends Sheldon and Missy for a university research study on twins, and Mary is unhappy when the test results go to Sheldon's head.

Sheldon and Amy's theory is proven by two physicists, who then try to kick Amy off the Nobel nomination. Bernadette has a big success at work.

Sheldon helps Bernadette and Howard navigate bureaucratic paperwork. Leonard is disappointed when his friends exclude him from a scientific project.

Penny tries to seduce an abstaining Leonard to ruin his 'donation' for her ex-boyfriend and his wife. Raj's cancelled bachelor party takes a turn.

The gang finds out Wil Wheaton hosts a celebrity Dungeons and Dragons game. Deception and betrayal are the path to make it to the one open seat.

While Bernadette is away and Howard is in charge of the kids, Sheldon finds a book on experimenting on kids. The guys plus Amy make a day of it.

Pemberton and Campbell charm America, so Sheldon and Amy bring Nobel laureates Kip Thorne, George Smoot and Frances Arnold to their side.

Amy has a meltdown due to the pressure associated with winning a Nobel Prize. Raj and Howard try to relive the good old days.

Raj is worried people won't take him seriously in his own field after publishing a paper that suggests he may have discovered alien life.

Dara Ó Briain extracts humour from current events with guests Rhys James, Neil Delamere, Milton Jones, Zoe Lyons, Sara Pascoe and Ahir Shah.

After their house is trashed without an obvious cause, a couple install video surveillance to record the chilling supernatural events in their house.

Frankie is sad when informed that her days of having kids are over. Sue and Axl are shocked when her roommate and Sean Donahue start flirting.

Frankie and Mike frantically attempt to shut off the water when the pipes burst. The Hecks call a meeting to deal with their bickering.

Mike's dislike of dentistry leads to escalating falsehoods to avoid having his toothache fixed. Brick attempts to write a Scottish-themed rap musical.

Melissa covered her huge lipoma with a sweatshirt for years. Tyler's fear of cancer stopped his head lumps being diagnosed and Tahj is covered in painful boils.

44-year old Erica binges on food when faced with adversity, and previous weight-loss surgery was unsuccessful. Can she get the support she needs to change her habits.

To Show Or Not To Show. Sacha wants a dress that pushes the envelope and helps her shine. And, new mum Amy wants a gown that will really wow her fiancé.

Sophie wants to show it all off for her wedding day but finding the line between sexy and trashy is proving tricky. Plus, Sasha is back for her first fitting.

Rochelle and her mother can only agree on one thing - a dress with a mermaid style silhouette. Bride Nicole is struggling with the idea of glitz on her frock.

Frankie is sad when informed that her days of having kids are over. Sue and Axl are shocked when her roommate and Sean Donahue start flirting.

Frankie and Mike frantically attempt to shut off the water when the pipes burst. The Hecks call a meeting to deal with their bickering.

Mike's dislike of dentistry leads to escalating falsehoods to avoid having his toothache fixed. Brick attempts to write a Scottish-themed rap musical.

When Mary's faith is shaken by a tragedy in the community, Sheldon becomes an unlikely ally.

When George Sr. asks Sheldon to keep a secret from Mary, the stress of not being honest drives Sheldon to hide out at Tam's for his first sleepover.

Dr. Sturgis recommends Sheldon and Missy for a university research study on twins, and Mary is unhappy when the test results go to Sheldon's head.

Sheldon and Amy's theory is proven by two physicists, who then try to kick Amy off the Nobel nomination. Bernadette has a big success at work.

Sheldon helps Bernadette and Howard navigate bureaucratic paperwork. Leonard is disappointed when his friends exclude him from a scientific project.

Penny tries to seduce an abstaining Leonard to ruin his 'donation' for her ex-boyfriend and his wife. Raj's cancelled bachelor party takes a turn.

The gang finds out Wil Wheaton hosts a celebrity Dungeons and Dragons game. Deception and betrayal are the path to make it to the one open seat.

While Bernadette is away and Howard is in charge of the kids, Sheldon finds a book on experimenting on kids. The guys plus Amy make a day of it.

Pemberton and Campbell charm America, so Sheldon and Amy bring Nobel laureates Kip Thorne, George Smoot and Frances Arnold to their side.

Amy has a meltdown due to the pressure associated with winning a Nobel Prize. Raj and Howard try to relive the good old days.

Raj is worried people won't take him seriously in his own field after publishing a paper that suggests he may have discovered alien life.

Lexie confesses to Sue that she has a crush on Axl. Mike hires high school coach Babbitt to pull the quarry softball team out of their slump.

Axl thinks the universe is trying to tell him something when he runs into just about all of his ex-girlfriends at a St. Patrick's Day party.

Bill Norwood is so upset with Mike for poaching his plumber their friendship could be at risk. Brick spends a weekend with Axl at college to party.

Mary clashes with Sheldon's drama teacher Mr. Lundy over plans for a Halloween haunted house fundraiser for the church.

Sheldon gets into trouble with fellow child genius Paige at the Science Museum, while George Sr. is forced to play therapist to Paige's parents.

When Meemaw gives Sheldon his first video game, it takes over their lives. Meanwhile, George Sr. gets jealous when Georgie bonds with Herschel.

Kripke has proof that Dr. Pemberton plagiarized his thesis, and Sheldon and Amy aren't sure whether they should turn him in or not.

Leonard is surprised when Beverly is kind to him on a visit, until he finds out the real reason she's there. Denise and Stuart overstay their welcome.

Everything changes as Amy and Sheldon await big news. Howard and Bernadette leave their kids, while Leonard and Penny keep a secret.

Bernadette and Howard leave their kids, Penny and Leonard try to keep a secret, Sheldon and Amy stick together, and Raj makes a new friend.

Brilliant physicists Leonard and Sheldon meet new neighbour Penny, who shows them that although they're smart, they know very little about real life.

Leonard volunteers to sign for a package to make a good impression on Penny, but things go terribly awry when he enlists Sheldon for help.

Leonard is depressed to learn that Penny is dating someone. Encouraged by his friends and fellow scientists, he asks a colleague out on a date.

Sheldon gets fired and explores what life has to offer outside physics, leaving Leonard to take drastic action to snap his friend out of his funk.

Andrea and Tammy get bad news about their wedding, and Amy's opportunity-of-a-lifetime may tear the family apart as Tammy makes a surprise request.

Nesha's BBW speed dating event gets off to a rocky start. Jaz pushes for independence and attempts to train Nesha and Nana for their 5K.

Dara Ó Briain extracts humour from current events with guests Rhys James, Neil Delamere, Milton Jones, Zoe Lyons, Sara Pascoe and Ahir Shah.