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After more than 20 people on a Native American reservation die suddenly from a flu-like disease, Navajo medicine men provide a clue that leads to a most unlikely killer.

Katie Parla takes chef Edward Delling-Williams on an exploration of Rome's diverse Esquilino district, where they visit local markets and taste street food specialties reflecting modern Roman life.

This early-morning news covers overnight events, breaking domestic and international news as well as a preview of the day's anticipated events. The program also presents regular reports from the worlds of business, entertainment and sports.

Stay informed with the latest breaking news and headlines.

Stay informed with the latest breaking news and headlines.

Stay informed with the latest breaking news and headlines.

Actress Amanda Peet; Winnie the Pooh celebrates 100 years; shopping expert Chassie Post; Today Food with Melissa Ben-Ishay.

Breast cancer treatments with Jill Martin and Dr. Elisa Port; shopping expert Adrianna Brach; what to read with Ana Huang; fitness expert Stephanie Mansour; nutritionist Joy Bauer.

Actress Amanda Peet; Today Food with chef Rasheeda Purdie; co-authors Jonathan Haidt and Catherine Price ("The Amazing Generation: Your Guide to Fun and Freedom in a Screen-Filled World"); Kashus Culpepper performs.

Local, national and international news.

Stay informed with the latest breaking news and headlines.

Chelsea Handler, Valerie Bertinelli and Yamaneika Saunders talk about the latest viral headlines in dating.

Chelsea Handler tells Drew about headlining The High and Mighty Tour; the dating hour continues with Chelsea, Yamaneika Saunders and comic Jared Freid sharing ghosting stories.

When a woman finds a body on a rural road outside of Indianapolis, police learn the victim might have been poisoned with mushrooms.

NBC News provides viewers with the latest national and international news; consumer, health and personal finance reporting; up-to-the-minute local news.

Local, national and international news.

Local, national and international news.

Local, national and international news.

Local, national and international news.

Local, national and international news.

Tom Llamas anchors the latest news, going beyond the headlines to see how lives are affected by the world around them.

News and features about performers, productions and the milieu.

A syndicated news magazine includes investigative reports, interviews with newsmakers, human interest stories and celebrity and pop-culture features.

The first Faithful is dramatically murdered; suspicion runs rife in the castle as accusations are thrown around and evidence is presented at a heated first roundtable; a life-or-death secret mission must be carried out in plain sight.

An injured woman's sudden disappearance from the hospital leads to a murder investigation; as an eyewitness to the crime, Brady partners with Benson's SVU to unravel a complex motive; an explosive discovery puts both squads in danger.

The hunt for a murder suspect uncovers a crime with shocking legal and ethical implications; Bruno must protect his squad during a raid on a suspect's home; Carisi and Price team up in court when Brady's interrogation tactics undermine the case.

News coverage to start the day.

Hailing from Rockefeller Center in the heart of New York City, Jimmy has made it his mission to make sure viewers end the day with a smile; each weeknight, he hosts A-list guests, from movie stars to athletes, comedians, public figures and everyone in between; he also delivers a signature nightly monologue, performs in topical comedy sketches, plays fan-favorite games, and presents recurring segme

Actress Dakota Johnson; former professional football coach Mike Tomlin.

News coverage to start the day.

Paid programming.

Kidd, Seager and Carver investigate a fire at the city stables; Kylie clashes with some of the firefighters over changes due to budget cuts; Herrmann struggles to keep it together as Cindy's condition worsens.

While at a real estate conference in St. Louis, a man finds his wife drowned in the bathtub in their hotel room.

Joined by local musicians and dancers, chef Catherine Fulvio hosts a lively barnyard bash that includes a menu of braised lamb, roasted squash, Guinness chocolate cake and Irish coffee.

This early-morning news covers overnight events, breaking domestic and international news as well as a preview of the day's anticipated events. The program also presents regular reports from the worlds of business, entertainment and sports.

Stay informed with the latest breaking news and headlines.

Stay informed with the latest breaking news and headlines.

Stay informed with the latest breaking news and headlines.

Women's health with Dr. Jennifer Ashton; Alex Warren performs.

The importance of family medical history; bee veterinarians; what to watch with Nikki Novak; Alex Warren performs.

Actress Danielle Brooks; Nate Berkus and Jeremiah Brent's Portugal home tour; podcaster Nayeema Raza; top tailgate gear with Meaghan Murphy.

Local, national and international news.

Stay informed with the latest breaking news and headlines.

Drew and Ross hit the headlines; Drew shares her must-haves for the perfect weekend in a brand-new edition of The Weekender.

Drew sits down with "Verity" stars Anne Hathaway and Josh Hartnett and author Colleen Hoover to discuss the upcoming dramatic film adaptation of the best-selling novel.

When Dee Warner vanishes from her farm, her family is alarmed as her car is still in the driveway and her wedding ring is left behind; after three years of countless leads and no answers, a single X-ray image reveals the truth.

NBC News provides viewers with the latest national and international news; consumer, health and personal finance reporting; up-to-the-minute local news.

Local, national and international news.

Local, national and international news.

Local, national and international news.

Local, national and international news.

Local, national and international news.

Tom Llamas anchors the latest news, going beyond the headlines to see how lives are affected by the world around them.

News and features about performers, productions and the milieu.

A syndicated news magazine includes investigative reports, interviews with newsmakers, human interest stories and celebrity and pop-culture features.

A bank heist turns deadly as the U.S. Marshals and FBI clash to bring down the fugitive, pitting Jane against Clare; Micah adjusts to working for Mike on the Secret Service while hiding a forbidden relationship.

Anchored by Lester Holt, "Dateline" is NBC's signature newsmagazine, bringing viewers storytelling at its best by putting the pieces together to present the full picture of real-life events. NBC News correspondents cover compelling stories and issues of the day, ranging from mystery and crime to in-depth investigations and breaking-news events.

News coverage to start the day.

TV host Conan O'Brien; Brandon Flowers talks and performs; actress Lauren Lapkus.

Actor Jon Hamm; actress Sabrina Impacciatore; comic Taylor Tomlinson.

News coverage to start the day.

Paid programming.

Cruz feels the burden of his increased responsibilities; Kidd, Gallo and Carver get caught in the middle of a gang war on a call; Herrmann wrangles Trudy for help lifting Cindy's mood.

A cunning serial rapist who leaves no decisive evidence forces investigators to rely on geographical profiling in their search for an identity; DNA from a cigarette butt may provide the final piece of evidence needed to catch the suspect.

A tropical oasis with spectacular views of the Santa Monica Mountains and Pacific Ocean; the mansion boasts five spacious bedrooms and eights baths.

Featuring several U.S. companies offering real jobs to America's veterans; career counselors and HR specialists share tailored insights on how to find suitable employment, as well as tips to help vets ease their transition to civilian life.

Host Christian Stevenson aka "DJ BBQ" explores unique and up-and-coming places across America.

A bespoke New York loft; an architectural beauty in Malibu.

Stay informed with the latest breaking news and headlines.

News headlines, interviews, and stories intended to inform, entertain, inspire and set the agenda each morning for Americans and help viewers with their finances, health and well-being.

Stay informed with the latest breaking news and headlines.

Sheinelle Jones explores some of the rarest animal species on Earth -- such as black rhinos and Amur leopards -- and their remarkable critter kids.

Dr. Rae and Peter travel to a Costa Rican reserve where former cattle ranches have transformed into a thriving ecosystem for wildlife; working with jaguar researchers, they uncover why these apex predators thrive as they hunt nesting sea turtles.

Dylan Dreyer heads to the wilds of Portugal, where she discovers a mysterious cat-like carnivore, playful wolf pups and a butterfly mystery.

Kelsey Grammer explores the bold ideas behind the Empire State Building, Independence Hall, the U.S. Constitution and the groundbreaking Human Genome Project.

Sheinelle Jones explores some of the rarest animal species on Earth -- such as black rhinos and Amur leopards -- and their remarkable critter kids.

From Road Atlanta in Braselton, Ga.

Following all the action from the world of horse racing.

Local, national and international news.

Tom Llamas anchors the latest news, going beyond the headlines to see how lives are affected by the world around them.

Preseason breakdown of Big Ten football team expectations.

From Los Angeles Memorial Coliseum in Los Angeles.

News coverage to start the day.

Host Dakota Johnson; Turnstile performs.

Reality-TV star Bozoma Saint John and fiancée Keely Watson kick off their fiancée-moon in Belgium, curated by competing luxury travel advisers June Kleier and Julie Shotmeyer of Global Travel Collection.

An empowering transformation for an ALS fighter and her family.

Turning a beloved teacher's fixer-upper into a forever home.

Pete Lee; Doug Williams; Charlie Viracola; Natasha Leggero; Owen Smith; Carlos Oscar; Ant; host Whitney Cummings.

Experiments reveal the secrets of color; making clouds of color with rainbow powder; how ink manufacturers create color.

Joined by local musicians and dancers, chef Catherine Fulvio hosts a lively barnyard bash that includes a menu of braised lamb, roasted squash, Guinness chocolate cake and Irish coffee.

Looking at some of the most intelligent animals on the planet.

An invitation to look at different exclusive vacation retreats around the world, including luxury hotels, hideaways and spa escapes.

A news magazine show covering entertainment news and celebrity reports; investigative reports dig into top stories and human interest headlines.

Stay informed with the latest breaking news and headlines.

Sharp conversational coverage of the week's news, along with in-depth profiles of the people and personalities shaping American culture, assessing the highs and lows of the week and looking ahead to the next one.

Interviews with public figures and those making news, setting the political agenda and spotlighting the impact Washington decision-making has on Americans.

How inventors are finding new and environmentally friendly ways to power the planet.

Paid programming.

These super-powered critters all live in or around water: from pelicans to alligators to stingrays and more, we'll dive deep to find out what makes them so amazing!

How to create a fire with lemons; how to survive contact with 50,000 volts of electricity.

Women's basketball experts weigh-in on the upcoming WNBA game.

All the latest basketball action from the WNBA.

Local, national and international news.

Tom Llamas anchors the latest news, going beyond the headlines to see how lives are affected by the world around them.

"Football Night in America" features host Maria Taylor, former NFL head coach and quarterback Jason Garrett, former NFL head coach Mike Tomlin and NFL insider Mike Florio recapping the day's NFL highlights.

The Detroit Lions clash with the Carolina Panthers in Week 4 at Bank of America stadium. Detroit enters following a 31-24 win over the Jets on September 27, while host Carolina aims to bounce back from a 21-18 loss to Cleveland the same day.

News coverage to start the day.

Author and evangelist Joel Osteen spreads his message of love and hope as he preaches at the 30,000-plus member Lakewood Church in Houston. The program can be seen in more than 100 countries. Osteen urges people to live at their full potential and form a close relationship with God.

Billy Gardell, Sheryl Underwood, Jamie Kennedy, Byron Allen, Caroline Rhea and Brad Williams.