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Aimee has a mohawk of cysts on her head. Plus, Edith's face markings and itchy skin condition turn out to be more than she expected.

A nervous Brick finds out that his girlfriend wants to kiss on Valentine's Day. Darrin asks Frankie and Mike to help with a scavenger hunt for Sue.

The Heck family learns about Darrin's marriage proposal to Sue. Meanwhile, Axl attempts to use his Psych class to cure Brick of his quirks and tics.

Frankie feels nothing but guilt when she realises that she and the family forgot to celebrate or even remember Brick's 13th birthday.

Elizabeth's head is covered with giant cauliflower-shaped bumps. Jamaal has been growing a strange knob on his bottom since he was just a boy.

Geno was raised with lots of love and food but now he's living with his mum and eating himself to death. He and his cousin pledge to both lose weight.

After failing to find the perfect mermaid gown, Jodie is open to new silhouettes, but is her entourage? Katrina wants a backless frock, but her crew has other plans.

One-of-a-kind bride Nicoletta arrives with crystals, sage, and a plan to marry herself. Paraplegic bride, Natalie hopes to experience that magical bridal feeling.

While Mary and George take a trip, Georgie freaks out when his girlfriend thinks she's pregnant. Dale and Meemaw work out their relationship issues.

While college orientation does not go as Sheldon planned, Mary is mistaken for a university student and invited to a party.

Sheldon's first day of college is derailed by his new philosophy teacher. Mary and Brenda live vicariously through Missy's first day of middle school.

Meemaw takes matters into her own hands when Sheldon's philosophy teacher, Professor Ericson, sends him into a tailspin.

Sheldon and his dad dine with President Hagemeyer and a university benefactor. Also, Dale and his ex-wife invite Meemaw to their son's wedding.

Sheldon campaigns to become Dr. Linkletter's lab assistant. Georgie enlists the drama teacher, to help with a surprising business venture.

Dr. Linkletter pushes Sheldon to make friends with his fellow students, and Georgie gets a pager.

Sheldon, Dr. Linkletter and Meemaw team up on a science experiment. Mary is jealous that Pastor Jeff and Brenda are spending so much time together.

When Wolowitz gets to work with world-renowned scientist, Stephen Hawking, Sheldon is willing to do anything to meet his hero.

Howard's wedding plans are in jeopardy after the guys throw him a bachelor party, and details of his sexual history are leaked online.

When NASA reschedules Howard's mission and puts his wedding plans in jeopardy, he's forced to face his fears - and Bernadette's dad.

When Howard and Bernadette decide they want to be married before his NASA space launch, the gang rushes to put on a wedding.

Howard discovers that he can't escape his mother - even in space! Back on earth, meanwhile, Raj turns his existence as a third wheel into an art form.

After learning Penny is thinking about breaking up with Leonard, Sheldon tries to intervene. Howard is being picked on in space by the astronauts.

While the pressure of being in space starts to take its toll on Howard, Amy feels threatened when Sheldon hires a young female assistant, Alex.

When Howard returns from space, he doesn't get the hero's welcome he expected. Meanwhile, Game Night turns into a battle of the sexes.

The gang celebrates Halloween at Stuart's comic book store. Leonard and Penny discover a new spark in their relationship with a scientific seduction.

Sheldon's friendship with renowned scientist Stephen Hawking is threatened by a game of 'Words with Friends.

Bernadette pressures Howard to move out of his mother's house. Sheldon finds himself caught in the middle of a fight between Amy and Wil Wheaton.

Howard and Raj try to understand why Sheldon disappears every afternoon at 2:45. Leonard and Penny wrestle with jealousy in their relationship.

When the University reassigns Sheldon's unused parking spot to Howard, the ensuing turf battle affects the whole gang.

Sheldon plays nursemaid to a sick Amy, while Howard attempts to bond with his father-in-law on an upcoming fishing trip.

Sheldon unwillingly revisits some Christmas memories during a lively game of Dungeons and Dragons, while Raj joins the girls for ladies' night out.

Sheldon is accused of sexual harassment at the University and winds up dragging Leonard, Raj and Howard into the fray.

Leonard's car is stolen when the guys take a road trip to a comic book convention in Bakersfield, dressed as Star Trek characters.

Outraged that he's being forced to work with his university nemesis, Barry Kripke, Sheldon faces a crisis of conscience.

When Sheldon and Leonard fight, it affects Penny and Amy's living arrangements. Meanwhile, Raj takes care of Mrs. Wolowitz while Howard is away.

While the guys try to give their significant others the perfect Valentine's Day, Raj and Stuart throw a lonely people party at the comic book store.

Roger returns and hope Dr. Lee can help with his gigantic nose growths. Christine has lost her essence due to a large growth on her shoulder.

Lookin' For Love In Lumpy Places. Gabriel has a huge growth on his clavicle but is terrified of surgery. Karen has dealt with painful, scaly feet for 22 years with no diagnosis.

Ruben is a personal trainer whose head growth has prevented him from seeing clients. Kaitlin has blue marks and scars due to long-term drug use.